├── LICENSE ├── README.md └── resources ├── temp ├── 一次最多加这么多.jpg ├── 三乙醇胺.jpg ├── 中间还是粉末.jpg ├── 倒置乳液瓶.jpg ├── 全家福.jpg ├── 全家福带字.jpg ├── 分装瓶.jpg ├── 卡波姆980.jpg ├── 可以搅拌的程度.jpg ├── 拆开乳液瓶的底部.jpg ├── 捅出来的活塞.jpg ├── 最终产物1.jpg ├── 最终产物2.jpg ├── 水.jpg ├── 活塞可以捅出来.jpg ├── 溶解后1.jpg ├── 溶解后2.jpg ├── 酒精.jpg └── 雌二醇.jpg /LICENSE: -------------------------------------------------------------------------------- 1 | Creative Commons Legal Code 2 | 3 | CC0 1.0 Universal 4 | 5 | CREATIVE COMMONS CORPORATION IS NOT A LAW FIRM AND DOES NOT PROVIDE 6 | LEGAL SERVICES. DISTRIBUTION OF THIS DOCUMENT DOES NOT CREATE AN 7 | ATTORNEY-CLIENT RELATIONSHIP. CREATIVE COMMONS PROVIDES THIS 8 | INFORMATION ON AN "AS-IS" BASIS. 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Affirmer understands and acknowledges that Creative Commons is not a 120 | party to this document and has no duty or obligation with respect to 121 | this CC0 or use of the Work. 122 | -------------------------------------------------------------------------------- /README.md: -------------------------------------------------------------------------------- 1 | # 雌二醇凝胶自制教程 2 | 3 | 本教程主要翻译自[Allie Castro的DIY Estrogel Guide](https://groups.io/g/MTFHRT/wiki/30843),同时包含我自己制作时的一些经验和改进,并增加了实际制作时的图片,为行文流畅删节部分次要内容 4 | 5 | 下文将指导你使用便于网络购买的一些工具制备雌二醇凝胶,如果你对更多的实验性雌二醇凝胶配方或基于免洗洗手液的配方感兴趣,可以参考[这份wiki](https://reddit.com/r/estrogel/wiki),这是原作者获得大部分信息的地方.该配方基于[这一专利](https://patents.google.com/patent/US20070154533A1/en)的第39页.经过调整,使用60%浓度的乙醇与更高浓度的雌二醇后,达到了雌二醇的最佳吸收水平[^1]. 6 | 7 | ## 风险 8 | - 网络购买原料可能含有对人体有害的杂质 9 | - 吸入卡波姆980可能会造成呼吸道问题 10 | - 眼睛接触到漂浮的卡波姆粉末可能让你的眼睛感到不适甚至对视力造成影响 11 | - 酸性的卡波姆溶液可能腐蚀皮肤 12 | - 雌二醇凝胶本身属于处方药,使用前请务必考虑自身情况 13 | 14 | ## 简单方法 15 | 购买免洗洗手液并加入雌二醇即可 16 | 17 | 这一方法的主要问题在于由于免洗洗手液的质地使其难以均匀搅拌,可能导致激素水平波动较大,并且其中用于消毒的化学成分可能会阻碍雌二醇的吸收 18 | 19 | ## 原料 20 | - `17-β雌二醇` 155元/10g 在一些平台可以尝试搜索`CAS 50-28-2` 目前已经无法在平台买到，可以联系以前卖过的店家客服在微信上购买 21 | - `卡波姆980` 55元/100g **应避免与空气相接触** 22 | - `三乙醇胺` 11元/100g 用于制作化妆品的便宜的三乙醇胺为黄色且有异香,而纯品是无色透明的 23 | - `蒸馏水` 2元/500ml 24 | - `乙醇` 15元/1L 需要浓度超过60% 25 | 26 | ## 工具 27 | - `真空乳液分装瓶` 3元 瓶底可以打开进行搅拌 **最好为棕色** 28 | - `量筒`或`电子秤` 电子秤需要精度1g,量程100g以上 29 | 30 | 制作成本通常约300-400元,雌二醇如果按高用量(每日5mg)计算足够使用约五年 31 | ![](./resources/%E5%85%A8%E5%AE%B6%E7%A6%8F%E5%B8%A6%E5%AD%97.jpg) 32 | 33 | ## 配方 34 | 下述配方针对100ml 0.24%雌二醇凝胶,是市场上凝胶浓度的四倍,你可以参考[MtF Wiki](https://mtf.wiki/zh-cn/docs/medicine/estrogen/gel/)来决定制作与使用方式 35 | 36 | 你需要先计算出需要使用的乙醇与蒸馏水,本文中按95%乙醇制作100ml凝胶计算,你可以使用[这个网站](https://ezcalc.me/alcohol-dilution-calculator/)计算你需要的比例 37 | 38 | - 63ml 95%乙醇 39 | - 37ml 蒸馏水 40 | - 1g 卡波姆980 41 | - 1.35g 三乙醇胺 42 | - 215mg 17-雌二醇 43 | 44 | ## 制作流程 45 | 1. 量取63ml或49.7g乙醇,倒入容器: 46 | 47 | ![](./resources/%E9%85%92%E7%B2%BE.jpg) 48 | 49 | 2. 量取215mg雌二醇加入乙醇,搅拌至完全溶解后溶液保持无色: 50 | 51 | ![](./resources/%E9%9B%8C%E4%BA%8C%E9%86%87.jpg) 52 | 53 | 3. 量取37ml蒸馏水加入溶液,雌二醇溶解度下降,产生白色沉淀后溶解: 54 | 55 | ![](./resources/%E6%B0%B4.jpg) 56 | 57 | 4. 量取1g卡波姆980缓慢多次加入溶液,避免接触或吸入空气中飘散的粉末,搅拌至完全溶解后溶液保持无色稍白，并放置一段时间再接着搅拌。建议参考[卡波姆的溶解方法](https://www.chemicalbook.com/NewsInfo_49117.htm): 58 | 59 | ![](./resources/%E6%BA%B6%E8%A7%A3%E5%90%8E2.jpg) 60 | 61 | 5. 将溶液转移至乳液瓶中: 62 | 63 | ![](./resources/%E5%80%92%E7%BD%AE%E4%B9%B3%E6%B6%B2%E7%93%B6.jpg) 64 | 65 | 6. 量取1.35g三乙醇胺加入溶液,搅拌至溶液变为悬胶不再随运动发生形变: 66 | 67 | ![](./resources/%E6%9C%80%E7%BB%88%E4%BA%A7%E7%89%A91.jpg) 68 | 69 | 7. 旋开按压泵排出气泡,调整活塞直至按压泵正常工作: 70 | 71 | ![](./resources/%E6%9C%80%E7%BB%88%E4%BA%A7%E7%89%A92.jpg) 72 | 73 | 8. 可尝试加入油酸,d-柠檬烯,肉豆蔻酸异丙酯等以提高吸收效率 74 | 75 | ## 使用结果 76 | 77 | 原作者结果：将成品涂抹于阴囊与大腿表面,早晚各一次,每次约1.5mL,持续一个月后睾酮降至29ng/dL,雌二醇达到326pg/mL 78 | 译者的结果：成品涂抹于大腿内侧,早晚各一次,每次约1.5mL,12小时后测得雌二醇133pg/mL 79 | 80 | ## 译者提示 81 | 82 | 1. 实测之后我觉得原配方还是太粘稠了.建议可以减半卡波姆和三乙醇胺的用量. 83 | 2. 关于提高吸收效率,我只试过橘子精油,但是我貌似会对这个东西过敏,涂抹后皮肤发红并且很痒. 84 | 85 | ## 友情链接 86 | 87 | [KristallWang/Estradiol-DIY](https://github.com/KristallWang/Estradiol-DIY) 有很多参考文献，建议想深入了解的小伙伴阅读 88 | 89 | ## License 90 | 91 | Apply [Creative Commons Zero v1.0 Universal License](https://raw.githubusercontent.com/lydlid/estrogel-diy-guide-zh_CN/main/LICENSE) for all contents temporarily, we're still trying to get the permission from [original author](mail://owl@owl.haus) to translate and publish it. 92 | 93 | Translated by [@Celes_tium](https://twitter.com/Celes_tium) 94 | 95 | [^1]: https://sci-hub.se/https://doi.org/10.1016/j.addr.2012.09.032 96 | -------------------------------------------------------------------------------- /resources/temp: -------------------------------------------------------------------------------- 1 | temp 2 | -------------------------------------------------------------------------------- /resources/一次最多加这么多.jpg: 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