├── manual.v3.4.pdf └── README.md /manual.v3.4.pdf: -------------------------------------------------------------------------------- https://raw.githubusercontent.com/mapleforest/HaploMerger2/HEAD/manual.v3.4.pdf -------------------------------------------------------------------------------- /README.md: -------------------------------------------------------------------------------- 1 | # HaploMerger2 2 | 3 | HaploMerger2 (HM2) is an important upgrade over HaploMerger. 4 | 5 | HM2 is an easy-to-use automated pipeline for improving geneome assembly in the post-assembly stage. It consists of a set of executables as well as wrappers for several third-part software. 6 | 7 | It is designed to untangle allelic relations between haplotype sequences in a highly-polymorphic diploid assembly, and then reconstruct and output two separated haploid sub-assemblies, the reference (the better one) and the alternative. 8 | 9 | HM2 also implements sensitive assembly error correction, a reliable gap-closing method and a hierarchical scaffolding procedure on haploid assembly. 10 | 11 | HaploMerger2 is freely available for acadamic use: https://github.com/mapleforest/HaploMerger2/releases/ 12 | 13 | # Citation 14 | 15 | * Shengfeng Huang, et al. HaploMerger2: rebuilding both haploid sub-assemblies from a heterozygous animal diploid genome assembly. submitted. 16 | 17 | * Shengfeng Huang, et al. HaploMerger: reconstructing allelic relationships for polymorphic diploid genome assemblies. Genome Res. 2012, 22(8):1581-1588. 18 | 19 | 20 | --------------------------------------------------------------------------------