├── .github └── workflows │ ├── mititools.yml │ └── validate_miti_yaml.yml ├── LICENSE ├── README.md ├── validation ├── validate_miti_yaml.py └── validation-schema.yaml └── yaml ├── 01-clinical.yaml ├── 02-biospecimen.yaml ├── 03-file.yaml ├── 04-channel.yaml ├── 05-ome-tiff-header.yaml ├── 06-processed-data.yaml ├── 07-cell.yaml └── 08-cell-state.yaml /.github/workflows/mititools.yml: -------------------------------------------------------------------------------- 1 | name: Build representations with MITI tools 2 | 3 | on: 4 | push: 5 | tags: 6 | - v* 7 | 8 | jobs: 9 | tools: 10 | runs-on: ubuntu-latest 11 | env: 12 | ZIP: 'miti_${{ github.ref_name }}.zip' 13 | steps: 14 | - uses: actions/checkout@v2 15 | - uses: actions/setup-python@v2 16 | with: 17 | python-version: '3.x' 18 | - run: | 19 | python -m pip install git+https://github.com/miti-consortium/mititools.git 20 | mititools generate --source-dir yaml/ 21 | zip -r ${{ env.ZIP }} yaml/ cv/ flatfields/ frictionless/ 22 | - uses: softprops/action-gh-release@v1 23 | with: 24 | body: Automatically generated by GitHub Actions for ${{ github.ref_name }} 25 | files: ${{ env.ZIP }} 26 | -------------------------------------------------------------------------------- /.github/workflows/validate_miti_yaml.yml: -------------------------------------------------------------------------------- 1 | name: Validate MITI YAML files 2 | 3 | on: [push, pull_request] 4 | 5 | jobs: 6 | build: 7 | runs-on: ubuntu-latest 8 | steps: 9 | - uses: actions/checkout@v2 10 | - uses: actions/setup-python@v2 11 | with: 12 | python-version: '3.x' # Version range or exact version of a Python version to use, using SemVer's version range syntax 13 | architecture: 'x64' # optional x64 or x86. Defaults to x64 if not specified 14 | - run: | 15 | pip install cerberus 16 | pip install pyyaml 17 | for f in ./yaml/*.yaml; do 18 | python validation/validate_miti_yaml.py "$f" validation/validation-schema.yaml 19 | done 20 | 21 | -------------------------------------------------------------------------------- /LICENSE: -------------------------------------------------------------------------------- 1 | MIT License 2 | 3 | Copyright (c) 2021 Laboratory of Systems Pharmacology @ Harvard 4 | 5 | Permission is hereby granted, free of charge, to any person obtaining a copy 6 | of this software and associated documentation files (the "Software"), to deal 7 | in the Software without restriction, including without limitation the rights 8 | to use, copy, modify, merge, publish, distribute, sublicense, and/or sell 9 | copies of the Software, and to permit persons to whom the Software is 10 | furnished to do so, subject to the following conditions: 11 | 12 | The above copyright notice and this permission notice shall be included in all 13 | copies or substantial portions of the Software. 14 | 15 | THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR 16 | IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, 17 | FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE 18 | AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER 19 | LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, 20 | OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE 21 | SOFTWARE. 22 | -------------------------------------------------------------------------------- /README.md: -------------------------------------------------------------------------------- 1 | # MITI: Minimum Information about Tissue Imaging 2 | 3 | Minimum Information about Tissue Images (MITI) reporting guidelines comprise minimal metadata for highly multiplexed tissue images and were developed in consultation with methods developers, experts in imaging metadata (e.g., DICOM and OME) and multiple large-scale atlasing projects; they are guided by existing standards and accommodate most multiplexed imaging technologies and both centralized and distributed data storage. 4 | 5 | The YAML files in this repository provide detailed specification of the standard, as outlined in the corresponding **[manuscript](https://arxiv.org/abs/2108.09499)**. Individual files capture attributes, their description and significance, but also additional information that is essential for validating specific files; this includes ensuring that data in each field has the correct data type and that it meets constraints on valid values. Each attribute is associated with one of the following data types: 6 | 7 | * `boolean`, `integer`, `float`, `string` - Standard data types representing boolean, integer, floating-point and character strings 8 | * `filename` - A valid [POSIX-portable](https://www.ibm.com/docs/en/zos/2.2.0?topic=locales-posix-portable-file-name-character-set) filename 9 | * `date` - A date specified in the [ISO 8601 standard](https://www.iso.org/iso-8601-date-and-time-format.html) YYYY-MM-DD 10 | * `doi` - A valid [DOI identifier](https://www.doi.org/) 11 | * `rrid` - A valid [Research Resource Identifier](https://scicrunch.org/resources) 12 | 13 | Valid values are specified as sets of predefined keywords for `string` and as [`min`, `max`] intervals for `integer` and `float` variables, where both `min` and `max` can be optionally omitted to define one-sided intervals. 14 | 15 | ## Community Participation 16 | This is a consensus-based community standard. Anyone with an interest can join the community, contribute to the schema design and implementation, and participate in the decision-making process. Community discussions should be limited to Github and `image.sc` forum in [#mcmicro](https://forum.image.sc/tag/mcmicro). 17 | 18 | Changes to MITI require a submission via `Github Issues` with the following information: 19 | 20 | * Scope and Field 21 | * Summary of changes 22 | * Example 23 | * Implementation as a pull request 24 | 25 | Please reach out to the governance board with questions about how to engage in community discussions or submit revisions. If the implementation needs a revision, the community can discuss and vote for the submission via Github for at least 30 days. 26 | 27 | ## Governance 28 | The MITI governance board members are expected to participate in strategic planning, approve changes to the governance model, and respond to community feedback. The board will resolve revisions/issues for which the community cannot reach a consensus in a reasonable timeframe. This board will remain for 18 months followed by a community-based voting of a new governance board (3-5 board members). New candidates can be proposed by board members, community members or via a direct application. We welcome and encourage participation by everyone! 29 | 30 | As of 2023-10-18, the MITI governance board comprises (i) **Denis Schapiro**, PhD, Research Group Leader at the Heidelberg University (Chair); (ii) **Adam Taylor**, PhD, Senior Research Scientist, Sage Bionetworks; (iii) **Sarah Arena**, MS, Data Scientist, Harvard Medical School 31 | 32 | ## Diversity Statement 33 | 34 | The MITI consortium welcomes and encourages participation by everyone. We are committed to being a community that everyone enjoys being part of. Although we may not always be able to accommodate each individual’s preferences, we try our best to treat everyone kindly. 35 | 36 | No matter how you identify yourself or how others perceive you: we welcome you. Though no list can hope to be comprehensive, we explicitly honour diversity in: age, culture, ethnicity, genotype, gender identity or expression, language, national origin, neurotype, phenotype, political beliefs, profession, race, religion, sexual orientation, socioeconomic status, subculture and technical ability, to the extent that these do not conflict with this code of conduct. 37 | 38 | ## Example 1 39 | 40 | The following YAML block defines a required attribute `Tumor tissue type` that relates to collection and processing of biospecimens. A valid field must be specified as a character string, using one of the pre-defined keywords: Primary Tumor, Local Tumor Recurrence, etc. 41 | 42 | ``` yaml 43 | Tumor tissue type: 44 | description: Text that describes the kind of disease present in the tumor specimen 45 | as related to a specific time point. 46 | category: Collection and Processing 47 | type: string 48 | valid-values: 49 | - Primary Tumor 50 | - Local Tumor Recurrence 51 | - Distant Tumor Recurrence 52 | - Metastatic 53 | - Premalignant 54 | significance: required 55 | ``` 56 | 57 | ## Example 2 58 | 59 | The following YAML block defines a recommended attribute `Cycle Number`, which must be specified as a 1-based index (i.e., an integer belonging to the one-sided interval `[1, Inf)`). 60 | 61 | ``` yaml 62 | Cycle Number: 63 | description: 'the cycle # in which the co-listed reagent(s) was(were) used' 64 | type: integer 65 | valid-values: 66 | min: 1.0 67 | significance: recommended 68 | ``` 69 | 70 | ## Endnotes 71 | 72 | We are thankful to the groups behind the following documents, from which we drew content and inspiration: 73 | 74 | * [The napari Code of Conduct](https://github.com/napari) 75 | -------------------------------------------------------------------------------- /validation/validate_miti_yaml.py: -------------------------------------------------------------------------------- 1 | from cerberus import Validator 2 | import yaml 3 | import sys 4 | import os 5 | 6 | v = Validator() 7 | 8 | def import_yaml(input_yaml): 9 | with open(input_yaml, 'r') as file: 10 | to_validate = yaml.safe_load(file) 11 | names = list(to_validate) 12 | attributes = list(map(lambda x: to_validate[x], names)) 13 | 14 | return(names, attributes) 15 | 16 | def import_schema(schema_path): 17 | with open(schema_path, 'r') as file: 18 | schema = yaml.safe_load(file) 19 | return(schema) 20 | 21 | def validation(names, attributes, schema): 22 | check = v.validate(attributes, schema) 23 | errors = v.errors 24 | return(names, check,errors) 25 | 26 | def main(): 27 | 28 | input_yaml = sys.argv[1] 29 | schema_path = sys.argv[2] 30 | 31 | names, attributes = import_yaml(input_yaml) 32 | 33 | schema = import_schema(schema_path) 34 | 35 | check = list(map(lambda x, y: validation(x, y, schema), names, attributes)) 36 | 37 | errors = list(filter(lambda c: c[1] == False, check)) 38 | if (len(errors) > 0): 39 | print("Validation errors found in " + os.path.basename + ": " +str(len(errors))) 40 | print(errors) 41 | sys.exit(1) 42 | else: 43 | print("Passed validation: " + os.path.basename(input_yaml)) 44 | 45 | 46 | 47 | if __name__ == "__main__": 48 | main() 49 | -------------------------------------------------------------------------------- /validation/validation-schema.yaml: -------------------------------------------------------------------------------- 1 | description: 2 | required: True 3 | type: string 4 | type: 5 | required: True 6 | type: string 7 | allowed: 8 | - boolean 9 | - integer 10 | - float 11 | - string 12 | - filename 13 | - date 14 | - doi 15 | - rrid 16 | significance: 17 | required: True 18 | type: 19 | - string 20 | - dict 21 | category: 22 | required: False 23 | type: string 24 | valid-values: 25 | required: False 26 | type: 27 | - list 28 | - dict 29 | -------------------------------------------------------------------------------- /yaml/01-clinical.yaml: -------------------------------------------------------------------------------- 1 | Participant ID: 2 | description: Participant Identifier 3 | type: string 4 | significance: required 5 | Species: 6 | description: Text that identifies species of tissue sample. 7 | type: string 8 | valid-values: 9 | - Human 10 | - Primate 11 | - Mouse 12 | - Other 13 | significance: required 14 | Ethnicity: 15 | description: Text designations that identify ethnicity. 16 | category: Demographics 17 | type: string 18 | valid-values: 19 | - Hispanic or Latino 20 | - Not Hispanic or Latino 21 | significance: required 22 | Gender: 23 | description: Text designations that identify gender. 24 | category: Demographics 25 | type: string 26 | valid-values: 27 | - Female 28 | - Male 29 | - non-binary 30 | - 'self-identify/other: (please specify)' 31 | significance: required 32 | Race: 33 | description: Text designations that identify race. 34 | category: Demographics 35 | type: string 36 | valid-values: 37 | - White 38 | - American Indian or Alaska native 39 | - Black or African American 40 | - Asian 41 | - Native Hawaiian or other Pacific islander 42 | - other 43 | significance: required 44 | Vital status at last follow up: 45 | description: The survival state of the person at the last follow up contact. 46 | category: Demographics 47 | type: string 48 | valid-values: 49 | - Alive 50 | - Dead 51 | significance: required 52 | Year of death: 53 | description: Numeric value to represent the year of the death of an individual. 54 | category: Demographics 55 | type: integer 56 | significance: recommended 57 | Cause of death: 58 | description: Text term to identify the cause of death for a patient. 59 | category: Demographics 60 | type: string 61 | valid-values: 62 | - Cancer Related 63 | - Cardiovascular Disorder NOS 64 | - End-stage Renal Disease 65 | - Infection 66 | - Not Cancer Related 67 | - Renal Disorder NOS 68 | - Spinal Muscular Atrophy 69 | - Surgical Complications 70 | - Toxicity 71 | significance: recommended 72 | Days to death: 73 | description: Age at the time of death expressed in the number of days since birth. 74 | category: Demographics 75 | type: integer 76 | significance: recommended 77 | Age at diagnosis: 78 | description: Age at the time of diagnosis expressed in the number of days since 79 | birth. 80 | category: Diagnosis 81 | type: integer 82 | significance: required 83 | Known genetic predisposition mutation: 84 | description: A yes/no/unknown indicator to identify whether there is a known genetic 85 | predisposition mutation present in the patient. 86 | category: Diagnosis 87 | type: string 88 | valid-values: 89 | - 'Yes' 90 | - 'No' 91 | - Unknown 92 | significance: recommended 93 | Hereditary cancer predisposition syndrome: 94 | description: Inherited genetic predisposition syndrome that confers heightened susceptibility 95 | to cancer in the patient. 96 | category: Diagnosis 97 | type: string 98 | valid-values: 99 | - Alpha-1antitrypsin 100 | - Attenuated familial adenomatous polyposis 101 | - BAP1mutant disease 102 | - Beckwith-Wiedemann 103 | - Biliary disorder 104 | - Birt-Hogg-Dube syndrome 105 | - Carney complex 106 | - Cirrhosis unknown etiology 107 | - Constitutional mismatch repair deficiency 108 | - Familial adenomatouspolyposis 109 | - Familial gastrointestinal stromal tumor 110 | - Familial pancreatic cancer 111 | - Familial prostate cancer 112 | - Familial renal cancer 113 | - Fanconi anemia 114 | - Glycogen Storage Disease 115 | - Gorlin syndrome 116 | - Hereditary breast–ovarian cancer syndrome 117 | - Hereditary diffuse gastric cancer 118 | - Hereditary leiomyoma-renal cell carcinoma 119 | - Hereditary melanoma 120 | - Hereditary mixed polyposis syndrome 121 | - Hereditary papillary RCC 122 | - Hereditary papillary renal cell carcinoma 123 | - Hereditary paraganglioma–pheochromocytoma syndrome 124 | - Hereditary renal oncocytoma 125 | - Hereditary retinoblastoma 126 | - Juvenile polyposis syndrome 127 | - Li-Fraumeni syndrome 128 | - Lynch syndrome 129 | - Melanoma–astrocytoma syndrome 130 | - Multiple endocrine neoplasia type I 131 | - Multiple endocrine neoplasia type II 132 | - MUTYH-associated polyposis 133 | - Nevoid basal cell carcinoma syndrome 134 | - Not Applicable 135 | - Not Reported 136 | - Peutz–Jeghers syndrome 137 | - Cowden syndrome 138 | - Rhabdoid tumor predisposition syndrome type I 139 | - Rhabdoid tumor predisposition syndrome type II 140 | - Rubinstein-Taybi syndrome 141 | - SDHassociated renal cancer 142 | - Serrated polyposis syndrome 143 | - Tuberous sclerosis complex 144 | - Turcotsyndrome 145 | - Tyrosinemia 146 | - Unknown 147 | - VonHippel-Lindau Syndrome 148 | significance: recommended 149 | Primary diagnosis: 150 | description: Text term used to describe the patient's histologic diagnosis. 151 | category: Diagnosis 152 | type: string 153 | valid-values: 154 | - Abdominal desmoid 155 | - Abdominal fibromatosis 156 | - Achromic nevus 157 | - Acidophil adenocarcinoma 158 | - Acidophil adenoma 159 | - Acidophil carcinoma 160 | - Acinar adenocarcinoma 161 | - Acinar adenocarcinoma sarcomatoid 162 | - Acinar adenoma 163 | - Acinar carcinoma 164 | - Acinar cell adenoma 165 | - Acinar cell carcinoma 166 | - Acinar cell cystadenocarcinoma 167 | - Acinar cell tumor 168 | - Acinic cell adenocarcinoma 169 | - Acinic cell adenoma 170 | - Acinic cell tumor 171 | - Acoustic neuroma 172 | - Acquired cystic disease-associated renal cell carcinoma (RCC) 173 | - Acquired tufted hemangioma 174 | - Acral lentiginous melanoma malignant 175 | - ACTH-producing tumor 176 | - Acute basophilic leukaemia 177 | - Acute bilineal leukemia 178 | - Acute biphenotypic leukemia 179 | - Acute erythremia 180 | - Acute erythremic myelosis 181 | - Acute erythroid leukaemia 182 | - Acute granulocytic leukemia 183 | - Acute leukemia Burkitt type 184 | - Acute leukemia NOS 185 | - Acute lymphatic leukemia 186 | - Acute lymphoblastic leukemia-lymphoma NOS 187 | - Acute lymphoblastic leukemia L2 type NOS 188 | - Acute lymphoblastic leukemia mature B-cell type 189 | - Acute lymphoblastic leukemia NOS 190 | - Acute lymphoblastic leukemia precursor cell type 191 | - Acute lymphocytic leukemia 192 | - Acute lymphoid leukemia 193 | - Acute megakaryoblastic leukaemia 194 | - Acute mixed lineage leukemia 195 | - Acute monoblastic and monocytic leukemia 196 | - Acute monoblastic leukemia 197 | - Acute monocytic leukemia 198 | - Acute myeloblastic leukemia 199 | - Acute myelocytic leukemia 200 | - Acute myelofibrosis 201 | - Acute myelogenous leukemia 202 | - Acute myeloid leukaemia t(8;21)(q22;q22) 203 | - Acute myelomonocytic leukemia 204 | - Acute myelomonocytic leukemia with abnormal eosinophils 205 | - Acute myelosclerosis NOS 206 | - Acute myloid leukemia 11q23 abnormalities 207 | - Acute non-lymphocytic leukemia 208 | - Acute panmyelosis with myelofibrosis 209 | - Acute panmyelosis NOS 210 | - Acute progressive histiocytosis X 211 | - Acute promyelocytic leukaemia PML-RAR-alpha 212 | - Acute promyelocytic leukaemia t(15;17)(q22;q11-12) 213 | - Acute promyelocytic leukemia NOS 214 | - Adamantinoma of long bones 215 | - Adamantinoma malignant 216 | - Adamantinoma NOS 217 | - Adenoacanthoma 218 | - Adenoameloblastoma 219 | - Adenocarcinoid tumor 220 | - Adenocarcinoma admixed with neuroendocrine carcinoma 221 | - Adenocarcinoma combined with other types of carcinoma 222 | - Adenocarcinoma with spindle cell metaplasia 223 | - Adenocarcinoma with squamous metaplasia 224 | - Adenocarcinoma cribriform comedo-type 225 | - Adenocarcinoma cylindroid 226 | - Adenocarcinoma diffuse type 227 | - Adenocarcinoma endocervical type 228 | - Adenocarcinoma intestinal type 229 | - Adenocarcinoma metastatic NOS 230 | - Adenocarcinoma NOS 231 | - Adenocarcinoma pancreatobiliary type 232 | - Adenocystic carcinoma 233 | - Adenofibroma NOS 234 | - Adenoid basal carcinoma 235 | - Adenoid cystic carcinoma 236 | - Adenolipoma 237 | - Adenolymphoma 238 | - Adenoma of nipple 239 | - Adenoma NOS 240 | - Adenomatoid odontogenic tumor 241 | - Adenomatoid tumor NOS 242 | - Adenomatosis NOS 243 | - Adenomatous polyp NOS 244 | - Adenomatous polyposis coli 245 | - Adenomyoepithelioma 246 | - Adenomyoepithelioma with carcinoma 247 | - Adenomyoma 248 | - Adenosarcoma 249 | - Adenosquamous carcinoma 250 | - Aggressive osteoblastoma 251 | - Aggressive systemic mastocytosis 252 | - Agnogenic myeloid metaplasia 253 | - AIN III 254 | - Aleukemic granulocytic leukemia 255 | - Aleukemic leukemia NOS 256 | - Aleukemic lymphatic leukemia 257 | - Aleukemic lymphocytic leukemia 258 | - Aleukemic lymphoid leukemia 259 | - Aleukemic monocytic leukemia 260 | - Aleukemic myelogenous leukemia 261 | - Aleukemic myeloid leukemia 262 | - ALK positive large B-cell lymphoma 263 | - Alpha cell tumor malignant 264 | - Alpha cell tumor NOS 265 | - Alpha heavy chain disease 266 | - Alveolar adenocarcinoma 267 | - Alveolar adenoma 268 | - Alveolar carcinoma 269 | - Alveolar cell carcinoma 270 | - Alveolar rhabdomyosarcoma 271 | - Alveolar soft part sarcoma 272 | - Amelanotic melanoma 273 | - Ameloblastic carcinoma 274 | - Ameloblastic fibro-odontoma 275 | - Ameloblastic fibro-odontosarcoma 276 | - Ameloblastic fibrodentinoma 277 | - Ameloblastic fibrodentinosarcoma 278 | - Ameloblastic fibroma 279 | - Ameloblastic fibrosarcoma 280 | - Ameloblastic odontosarcoma 281 | - Ameloblastic sarcoma 282 | - Ameloblastoma malignant 283 | - Ameloblastoma NOS 284 | - AML M6 285 | - Anal intraepithelial neoplasia grade III 286 | - Anal intraepithelial neoplasia low grade 287 | - Anaplastic astrocytoma IDH-mutant 288 | - Anaplastic astrocytoma IDH-wildtype 289 | - Anaplastic large B-cell lymphoma 290 | - Anaplastic large cell lymphoma ALK negative 291 | - Anaplastic large cell lymphoma ALK positive 292 | - Anaplastic large cell lymphoma CD30+ 293 | - Anaplastic large cell lymphoma NOS 294 | - Anaplastic large cell lymphoma T cell and Null cell type 295 | - Anaplastic medulloblastoma 296 | - Anaplastic oligoastrocytoma 297 | - Anaplastic oligodendroglioma IDH-mutant and 1p/19q-codeleted 298 | - Anaplastic pleomorphic xanthroastrocytoma 299 | - Ancient schwannoma 300 | - Androblastoma benign 301 | - Androblastoma malignant 302 | - Androblastoma NOS 303 | - Angioblastic meningioma 304 | - Angioblastoma 305 | - Angiocentric glioma 306 | - Angiocentric immunoproliferative lesion 307 | - Angiocentric T-cell lymphoma 308 | - Angioendothelioma 309 | - Angioendotheliomatosis 310 | - Angiofibroma NOS 311 | - Angioimmunoblastic lymphadenopathy 312 | - Angioimmunoblastic lymphoma 313 | - Angioimmunoblastic T-cell lymphoma 314 | - Angiokeratoma 315 | - Angioleiomyoma 316 | - Angiolipoma NOS 317 | - Angioma NOS 318 | - Angiomatoid fibrous histiocytoma 319 | - Angiomatous meningioma 320 | - Angiomyofibroblastoma 321 | - Angiomyolipoma 322 | - Angiomyoma 323 | - Angiomyosarcoma 324 | - Angiomyxoma 325 | - Angiosarcoma 326 | - Angiotropic lymphoma 327 | - Atypical adenoma 328 | - Atypical carcinoid tumor 329 | - Atypical choroid plexus papilloma 330 | - Atypical chronic myeloid leukemia BCR/ABL negative 331 | - Atypical chronic myeloid leukemia Philadelphia chromosome (Ph1) negative 332 | - Atypical fibrous histiocytoma 333 | - Atypical fibroxanthoma 334 | - Atypical follicular adenoma 335 | - Atypical hyperplasia/Endometrioid intraepithelial neoplasm 336 | - Atypical leiomyoma 337 | - Atypical lipoma 338 | - Atypical medullary carcinoma 339 | - Atypical meningioma 340 | - Atypical polypoid adenomyoma 341 | - Atypical proliferating clear cell tumor 342 | - Atypical proliferating serous tumor 343 | - Atypical proliferative endometrioid tumor 344 | - Atypical proliferative mucinous tumor 345 | - Atypical proliferative papillary serous tumor 346 | - Atypical teratoid/rhabdoid tumor 347 | - B cell lymphoma NOS 348 | - B-ALL 349 | - B-cell lymphocytic leukemia/small lymphocytic lymphoma 350 | - B-cell lymphoma unclassifiable with features intermediate between diffuse large 351 | B-cell lymphoma and Burkitt lymphoma 352 | - B-cell lymphoma unclassifiable with features intermediate between diffuse large 353 | B-cell lymphoma and classical Hodgkin lymphoma 354 | - Balloon cell melanoma 355 | - Balloon cell nevus 356 | - BALT lymphoma 357 | - Basal cell adenocarcinoma 358 | - Basal cell adenoma 359 | - Basal cell carcinoma desmoplastic type 360 | - Basal cell carcinoma fibroepithelial 361 | - Basal cell carcinoma micronodular 362 | - Basal cell carcinoma morpheic 363 | - Basal cell carcinoma nodular 364 | - Basal cell carcinoma NOS 365 | - Basal cell epithelioma 366 | - Basal cell tumor 367 | - Basaloid carcinoma 368 | - Basaloid squamous cell carcinoma 369 | - Basophil adenocarcinoma 370 | - Basophil adenoma 371 | - Basophil carcinoma 372 | - Basosquamous carcinoma 373 | - Bednar tumor 374 | - Bellini duct carcinoma 375 | - Benign cystic nephroma 376 | - Benign fibrous histiocytoma 377 | - Beta cell adenoma 378 | - Beta cell tumor malignant 379 | - Bile duct adenocarcinoma 380 | - Bile duct adenoma 381 | - Bile duct carcinoma 382 | - Bile duct cystadenocarcinoma 383 | - Bile duct cystadenoma 384 | - Biliary intraepithelial neoplasia grade 3 385 | - Biliary intraepithelial neoplasia high grade 386 | - Biliary intraepithelial neoplasia low grade 387 | - Biliary papillomatosis 388 | - Biphenotypic sinonasal sarcoma 389 | - Bizarre leiomyoma 390 | - Black adenoma 391 | - Blast cell leukemia 392 | - Blastic NK cell lymphoma 393 | - Blastic plasmacytoid dendritic cell neoplasm 394 | - Blastoma NOS 395 | - Blue nevus malignant 396 | - Blue nevus NOS 397 | - Botryoid sarcoma 398 | - Bowen disease 399 | - Brenner tumor borderline malignancy 400 | - Brenner tumor malignant 401 | - Brenner tumor NOS 402 | - Brenner tumor proliferating 403 | - Bronchial adenoma carcinoid 404 | - Bronchial adenoma cylindroid 405 | - Bronchial adenoma NOS 406 | - Bronchial-associated lymphoid tissue lymphoma 407 | - Bronchio-alveolar carcinoma mixed mucinous and non-mucinous 408 | - Bronchio-alveolar carcinoma mucinous 409 | - Bronchiolar adenocarcinoma 410 | - Bronchiolar carcinoma 411 | - Bronchiolo-alveolar adenocarcinoma NOS 412 | - Bronchiolo-alveolar carcinoma Clara cell 413 | - Bronchiolo-alveolar carcinoma Clara cell and goblet cell type 414 | - Bronchiolo-alveolar carcinoma goblet cell type 415 | - Bronchiolo-alveolar carcinoma indeterminate type 416 | - Bronchiolo-alveolar carcinoma non-mucinous 417 | - Bronchiolo-alveolar carcinoma NOS 418 | - Bronchiolo-alveolar carcinoma type II pneumocyte and goblet cell type 419 | - Bronchiolo-alveolar carcinoma; type II pneumocyte 420 | - Brooke tumor 421 | - Brown fat tumor 422 | - Burkitt cell leukemia 423 | - Burkitt lymphoma NOS (Includes all variants) 424 | - Burkitt tumor 425 | - Burkitt-like lymphoma 426 | - C cell carcinoma 427 | - c-ALL 428 | - Calcifying epithelial odontogenic tumor 429 | - Calcifying epithelioma of Malherbe 430 | - Calcifying nested epithelial stromal tumor 431 | - Calcifying odontogenic cyst 432 | - Canalicular adenoma 433 | - Cancer 434 | - Capillary hemangioma 435 | - Capillary lymphangioma 436 | - Carcinofibroma 437 | - Carcinoid tumor of uncertain malignant potential 438 | - Carcinoid tumor argentaffin malignant 439 | - Carcinoid tumor argentaffin NOS 440 | - Carcinoid tumor NOS 441 | - Carcinoid tumor NOS of appendix 442 | - Carcinoid NOS 443 | - Carcinoid NOS of appendix 444 | - Carcinoma in a polyp NOS 445 | - Carcinoma in adenomatous polyp 446 | - Carcinoma in pleomorphic adenoma 447 | - Carcinoma in situ in a polyp NOS 448 | - Carcinoma in situ in adenomatous polyp 449 | - Carcinoma in situ NOS 450 | - Carcinoma showing thymus-like differentiation 451 | - Carcinoma showing thymus-like element 452 | - Carcinoma simplex 453 | - Carcinoma with apocrine metaplasia 454 | - Carcinoma with chondroid differentiation 455 | - Carcinoma with neuroendocrine differentiation 456 | - Carcinoma with osseous differentiation 457 | - Carcinoma with osteoclast-like giant cells 458 | - Carcinoma with other types mesenchymal differentiation 459 | - Carcinoma with productive fibrosis 460 | - Carcinoma anaplastic NOS 461 | - Carcinoma diffuse type 462 | - Carcinoma intestinal type 463 | - Carcinoma metastatic NOS 464 | - Carcinoma NOS 465 | - Carcinoma undifferentiated NOS 466 | - Carcinomatosis 467 | - Carcinosarcoma embryonal 468 | - Carcinosarcoma NOS 469 | - Carotid body paraganglioma 470 | - Carotid body tumor 471 | - Cartilaginous exostosis 472 | - CASTLE 473 | - Cavernous hemangioma 474 | - Cavernous lymphangioma 475 | - Cellular angiofibroma 476 | - Cellular blue nevus 477 | - Cellular ependymoma 478 | - Cellular fibroma 479 | - Cellular leiomyoma 480 | - Cellular schwannoma 481 | - Cementifying fibroma 482 | - Cemento-ossifying fibroma 483 | - Cementoblastoma benign 484 | - Cementoma NOS 485 | - Central neuroblastoma 486 | - Central neurocytoma 487 | - Central odontogenic fibroma 488 | - Central osteosarcoma 489 | - Central primitive neuroectodermal tumor NOS 490 | - Cerebellar liponeurocytoma 491 | - Cerebellar sarcoma NOS 492 | - Ceruminous adenocarcinoma 493 | - Ceruminous adenoma 494 | - Ceruminous carcinoma 495 | - Cervical intraepithelial neoplasia grade III 496 | - Cervical intraepithelial neoplasia low grade 497 | - Chemodectoma 498 | - Chief cell adenoma 499 | - Chloroma 500 | - Cholangiocarcinoma 501 | - Cholangioma 502 | - Chondroblastic osteosarcoma 503 | - Chondroblastoma malignant 504 | - Chondroblastoma NOS 505 | - Chondroid chordoma 506 | - Chondroid lipoma 507 | - Chondroid syringoma 508 | - Chondroma NOS 509 | - Chondromatosis NOS 510 | - Chondromatous giant cell tumor 511 | - Chondromyxoid fibroma 512 | - Chondrosarcoma grade 2/3 513 | - Chondrosarcoma NOS 514 | - Chordoid glioma 515 | - Chordoid glioma of third ventricle 516 | - Chordoid meningioma 517 | - Chordoma NOS 518 | - Chorioadenoma 519 | - Chorioadenoma destruens 520 | - Chorioangioma 521 | - Choriocarcinoma combined with embryonal carcinoma 522 | - Choriocarcinoma combined with other germ cell elements 523 | - Choriocarcinoma combined with teratorna 524 | - Choriocarcinoma NOS 525 | - Chorioepithelioma 526 | - Chorionepithelioma 527 | - Choroid plexus carcinoma 528 | - Choroid plexus papilloma anaplastic 529 | - Choroid plexus papilloma malignant 530 | - Choroid plexus papilloma NOS 531 | - Chromaffin paraganglioma 532 | - Chromaffin tumor 533 | - Chromaffinoma 534 | - Chromophobe adenocarcinoma 535 | - Chromophobe adenoma 536 | - Chromophobe carcinoma 537 | - Chromophobe cell renal carcinoma 538 | - Chronic eosinophilic leukemia NOS 539 | - Chronic erythremia 540 | - Chronic granulocytic leukemia BCR/ABL 541 | - Chronic granulocytic leukemia NOS 542 | - Chronic granulocytic leukemia Philadelphia chromosome (Ph1) positive 543 | - Chronic granulocytic leukemia t(9;22)(q34;q11) 544 | - Chronic idiopathic myelofibrosis 545 | - Chronic leukemia NOS 546 | - Chronic lymphatic leukemia 547 | - Chronic lymphocytic leukemia 548 | - Chronic lymphocytic leukemia B-cell type (includes all variants of BCLL) 549 | - Chronic lymphoid leukemia 550 | - Chronic lymphoproliferative disorder of NK cells 551 | - Chronic monocytic leukemia 552 | - Chronic myelocytic leukemia NOS 553 | - Chronic myelogenous leukemia BCR-ABL positive 554 | - Chronic myelogenous leukemia Philadelphia chromosome (Ph 1) positive 555 | - Chronic myelogenous leukemia t(9;22)(q34;q11) 556 | - Chronic myeloid leukemia NOS 557 | - Chronic myelomonocytic leukemia in transformation 558 | - Chronic myelomonocytic leukemia NOS 559 | - Chronic myelomonocytic leukemia Type 1 560 | - Chronic myelomonocytic leukemia Type II 561 | - Chronic myeloproliferative disease NOS 562 | - Chronic myeloproliferative disorder 563 | - Chronic neutrophilic leukemia 564 | - CIN III with severe dysplasia 565 | - Cin III NOS 566 | - Circumscribed arachnoidal cerebellar sarcoma 567 | - Classical Hodgkin lymphoma lymphocyte depletion diffuse fibrosis 568 | - Classical Hodgkin lymphoma lymphocyte depletion NOS 569 | - Classical Hodgkin lymphoma lymphocyte depletion reticular 570 | - Classical Hodgkin lymphoma lymphocyte-rich 571 | - Classical Hodgkin lymphoma mixed cellularity NOS 572 | - Classical Hodgkin lymphoma nodular sclerosis cellular phase 573 | - Classical Hodgkin lymphoma nodular sclerosis grade 1 574 | - Classical Hodgkin lymphoma nodular sclerosis grade 2 575 | - Classical Hodgkin lymphoma nodular sclerosis NOS 576 | - Clear cell (glycogen-rich) urothelial carcinoma 577 | - Clear cell adenocarcinofibroma 578 | - Clear cell adenocarcinoma mesonephroid 579 | - Clear cell adenocarcinoma NOS 580 | - Clear cell adenofibroma 581 | - Clear cell adenofibroma of borderline malignancy 582 | - Clear cell adenoma 583 | - Clear cell carcinoma 584 | - Clear cell chondrosarcoma 585 | - Clear cell cystadenocarcinofibroma 586 | - Clear cell cystadenofibroma 587 | - Clear cell cystadenofibroma of borderline malignancy 588 | - Clear cell cystadenoma 589 | - Clear cell cystic tumor of borderline malignancy 590 | - Clear cell ependymoma 591 | - Clear cell hidradenoma 592 | - Clear cell meningioma 593 | - Clear cell odontogenic carcinoma 594 | - Clear cell odontogenic tumor 595 | - Clear cell sarcoma of kidney 596 | - Clear cell sarcoma NOS 597 | - Clear cell sarcoma of tendons and aponeuroses 598 | - Clear cell tumor NOS 599 | - Cloacogenic carcinoma 600 | - CNS Embryonal tumor with rhabdoid features 601 | - Codman tumor 602 | - Collecting duct carcinoma 603 | - Colloid adenocarcinoma 604 | - Colloid adenoma 605 | - Colloid carcinoma 606 | - Columnar cell papilloma 607 | - Combined carcinoid and adenocarcinoma 608 | - Combined hepatocellular carcinoma and cholangiocarcinoma 609 | - Combined large cell neuroendocrine carcinoma 610 | - Combined small cell carcinoma 611 | - Combined small cell-adenocarcinoma 612 | - Combined small cell-large carcinoma 613 | - Combined small cell-squamous cell carcinoma 614 | - Combined/mixed carcinoid and adenocarcinoma 615 | - Ductal carcinoma in situ NOS 616 | - Ductal carcinoma in situ papillary 617 | - Ductal carcinoma in situ solid type 618 | - Ductal carcinoma cribriform type 619 | - Ductal carcinoma NOS 620 | - Ductal intraepithelial neoplasia 3 621 | - Ductal papilloma 622 | - Dysembryoplastic neuroepithelial tumor 623 | - Dysgerminoma 624 | - Dysplastic gangliocytoma of cerebellum (Lhermitte-Duclos) 625 | - Dysplastic nevus 626 | - EBV positive diffuse large B-cell lymphoma of the elderly 627 | - EC cell carcinoid 628 | - Eosinophil adenocarcinoma 629 | - Eosinophil adenoma 630 | - Eosinophil carcinoma 631 | - Eosinophilic granuloma 632 | - Eosinophilic leukemia 633 | - Ependymoblastoma 634 | - Ependymoma anaplastic 635 | - Ependymoma NOS 636 | - Ependymoma RELA fusion-positive 637 | - Epidermoid carcinoma in situ with questionable stromal invasion 638 | - Epidermoid carcinoma in situ NOS 639 | - Epidermoid carcinoma keratinizing 640 | - Epidermoid carcinoma large cell nonkeratinizing 641 | - Epidermoid carcinoma NOS 642 | - Epidermoid carcinoma small cell nonkeratinizing 643 | - Epidermoid carcinoma spindle cell 644 | - Epithelial ependymoma 645 | - Epithelial tumor benign 646 | - Epithelial tumor malignant 647 | - Epithelial-myoepithelial carcinoma 648 | - Epithelioid and spindle cell nevus 649 | - Epithelioid cell melanoma 650 | - Epithelioid cell nevus 651 | - Epithelioid cell sarcoma 652 | - Epithelioid glioblastoma 653 | - Epithelioid hemangioendothelioma malignant 654 | - Epithelioid hemangioendothelioma NOS 655 | - Epithelioid hemangioma 656 | - Epithelioid leiomyoma 657 | - Epithelioid leiomyosarcoma 658 | - Epithelioid malignant peripheral nerve sheath tumor 659 | - Epithelioid mesothelioma benign 660 | - Epithelioid mesothelioma malignant 661 | - Epithelioid mesothelioma NOS 662 | - Epithelioid MPNST 663 | - Epithelioid sarcoma 664 | - Epithelioma adenoides cysticum 665 | - Epithelioma benign 666 | - Epithelioma malignant 667 | - Epithelioma NOS 668 | - Erythremic myelosis NOS 669 | - Erythroleukemia 670 | - Esophageal glandular dysplasia (intraepithelial neoplasia) high grade 671 | - Esophageal glandular dysplasia (intraepithelial neoplasia) low grade 672 | - Esophageal intraepithelial neoplasia high grade 673 | - Esophageal squamous intraepithelial neoplasia (dysplasia) high grade 674 | - Esophageal squamous intraepithelial neoplasia (dysplasia) low grade 675 | - Essential hemorrhagic thrombocythaemia 676 | - Essential thrombocythemia 677 | - Esthesioneuroblastoma 678 | - Esthesioneurocytoma 679 | - Esthesioneuroepithelioma 680 | - Ewing sarcoma 681 | - Ewing tumor 682 | - Extra-abdominal desmoid 683 | - Extra-adrenal paraganglioma malignant 684 | - Extra-adrenal paraganglioma NOS 685 | - Extracutaneous mastocytoma 686 | - Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue 687 | - Extranodal NK/T-cell lymphoma nasal type 688 | - Extraosseous plasmacytoma 689 | - Extraventricular neurocytoma 690 | - Familial polyposis coli 691 | - Fascial fibroma 692 | - Fascial fibrosarcoma 693 | - Fetal adenocarcinoma 694 | - Fetal adenoma 695 | - Fetal fat cell lipoma 696 | - Fetal lipoma NOS 697 | - Fetal lipomatosis 698 | - Fetal rhabdomyoma 699 | - Fibrillary astrocytoma 700 | - Fibro-osteoma 701 | - Fibroadenoma NOS 702 | - Fibroameloblastic odontoma 703 | - Fibroblastic liposarcoma 704 | - Fibroblastic meningioma 705 | - Fibroblastic osteosarcoma 706 | - Fibroblastic reticular cell tumor 707 | - Fibrochondrosarcoma 708 | - Fibroepithelial basal cell carcinoma Pinkus type 709 | - Fibroepithelioma of Pinkus type 710 | - Fibroepithelioma NOS 711 | - Fibrofolliculoma 712 | - Fibroid uterus 713 | - Fibrolipoma 714 | - Fibroliposarcoma 715 | - Fibromatosis-like metaplastic carcinoma 716 | - Fibroma NOS 717 | - Fibromyoma 718 | - Fibromyxolipoma 719 | - Fibromyxoma 720 | - Fibromyxosarcoma 721 | - Fibrosarcomatous dermatofibrosarcoma protuberans 722 | - Fibrosarcoma NOS 723 | - Fibrous astrocytoma 724 | - Fibrous histiocytoma of tendon sheath 725 | - Fibrous histiocytoma NOS 726 | - Fibrous meningioma 727 | - Fibrous mesothelioma benign 728 | - Fibrous mesothelioma malignant 729 | - Fibrous mesothelioma NOS 730 | - Fibrous papule of nose 731 | - Fibroxanthoma malignant 732 | - Fibroxanthoma NOS 733 | - Flat adenoma 734 | - Flat intraepithelial glandular neoplasia high grade 735 | - Flat intraepithelial neoplasia high grade 736 | - Florid osseous dysplasia 737 | - Haemangioblastoma 738 | - Haemangiosarcoma 739 | - Hairy cell leukaemia variant 740 | - Hairy cell leukemia 741 | - Hairy cell leukemia variant 742 | - Hairy nevus 743 | - Halo nevus 744 | - Hand-Schuller-Christian disease 745 | - Heavy chain disease NOS 746 | - Hemangioblastic meningioma 747 | - Hemangioendothelial sarcoma 748 | - Hemangioendothelioma benign 749 | - Hemangioendothelioma malignant 750 | - Hemangioendothelioma NOS 751 | - Hemangioma simplex 752 | - Hemangioma NOS 753 | - Hemangiopericytic meningioma 754 | - Hemangiopericytoma benign 755 | - Hemangiopericytoma malignant 756 | - Hemangiopericytoma NOS 757 | - Hemolymphangioma 758 | - Hepatoblastoma 759 | - Hepatoblastoma epithelioid 760 | - Hepatoblastoma mixed epithelial-mesenchymal 761 | - Hepatocarcinoma 762 | - Hepatocellular adenoma 763 | - Hepatocholangiocarcinoma 764 | - Hepatoid adenocarcinoma 765 | - Hepatoid carcinoma 766 | - Hepatoid yolk sac tumor 767 | - Hepatoma benign 768 | - Hepatoma malignant 769 | - Hepatoma NOS 770 | - Hepatosplenic T-cell lymphoma 771 | - Hepatosplenic gamma-delta cell lymphoma 772 | - Hereditary leiomyomatosis & RCC-associated renal cell carcinoma 773 | - Hibernoma 774 | - Hidradenocarcinoma 775 | - Hidradenoma papilliferum 776 | - Hidradenoma NOS 777 | - Hidrocystoma 778 | - High-grade neuroendocrine carcinoma 779 | - High-grade serous carcinoma 780 | - High grade surface osteosarcoma 781 | - Hilar cell tumor 782 | - Hilus cell tumor 783 | - Histiocyte-rich large B-cell lymphoma 784 | - Histiocytic medullary reticulosis 785 | - Histiocytic sarcoma 786 | - Histiocytoid hemangioma 787 | - Histiocytoma NOS 788 | - Histiocytosis X NOS 789 | - Hodgkin disease lymphocyte predominance diffuse 790 | - Hodgkin disease lymphocyte predominance NOS 791 | - Hodgkin disease lymphocytic-histiocytic predominance 792 | - Hodgkin disease nodular sclerosis lymphocyte depletion 793 | - Hodgkin disease nodular sclerosis lymphocyte predominance 794 | - Hodgkin disease nodular sclerosis mixed cellularity 795 | - Hodgkin disease nodular sclerosis NOS 796 | - Hodgkin disease nodular sclerosis syncytial variant 797 | - Hodgkin disease NOS 798 | - Hodgkin granuloma 799 | - Hodgkin lymphoma lymphocyte depletion diffuse fibrosis 800 | - Hodgkin lymphoma lymphocyte depletion NOS 801 | - Hodgkin lymphoma lymphocyte depletion reticular 802 | - Hodgkin lymphoma lymphocyte predominance nodular 803 | - Hodgkin lymphoma lymphocyte-rich 804 | - Hodgkin lymphoma mixed cellularity NOS 805 | - Hodgkin lymphoma nodular lymphocyte predominance 806 | - Hodgkin lymphoma nodular sclerosis cellular phase 807 | - Hodgkin lymphoma nodular sclerosis grade 1 808 | - Hodgkin lymphoma nodular sclerosis grade 2 809 | - Hodgkin lymphoma nodular sclerosis NOS 810 | - Hodgkin lymphoma NOS 811 | - Hodgkin paragranuloma nodular 812 | - Hodgkin paragranuloma NOS 813 | - Hodgkin sarcoma 814 | - Hurthle cell adenocarcinoma 815 | - Hurthle cell adenoma 816 | - Hurthle cell carcinoma 817 | - Hurthle cell tumor 818 | - Hutchinson melanotic freckle NOS 819 | - Hyalinizing trabecular adenoma 820 | - Hydatid mole 821 | - Infiltrating and papillary adenocarcinoma 822 | - Infiltrating angiolipoma 823 | - Infiltrating basal cell carcinoma non-sclerosing 824 | - Infiltrating basal cell carcinoma NOS 825 | - Infiltrating basal cell carcinoma sclerosing 826 | - Infiltrating duct adenocarcinoma 827 | - Infiltrating duct and colloid carcinoma 828 | - Infiltrating duct and cribriform carcinoma 829 | - Infiltrating duct and lobular carcinoma 830 | - Infiltrating duct and lobular carcinoma in situ 831 | - Infiltrating duct and mucinous carcinoma 832 | - Infiltrating duct and tubular carcinoma 833 | - Infiltrating duct carcinoma NOS 834 | - Infiltrating duct mixed with other types of carcinoma 835 | - Infiltrating ductular carcinoma 836 | - Infiltrating lipoma 837 | - Infiltrating lobular carcinoma and ductal carcinoma in situ 838 | - Infiltrating lobular carcinoma NOS 839 | - Infiltrating lobular mixed with other types of carcinoma 840 | - Infiltrating papillary adenocarcinoma 841 | - Inflammatory adenocarcinoma 842 | - Inflammatory carcinoma 843 | - Inflammatory liposarcoma 844 | - Inflammatory myofibroblastic tumor 845 | - Insular carcinoma 846 | - Insulinoma malignant 847 | - Insulinoma NOS 848 | - Interdigitating cell sarcoma 849 | - Interdigitating dendritic cell sarcoma 850 | - Intermediate and giant congenital nevus 851 | - Interstitial cell tumor benign 852 | - Interstitial cell tumor malignant 853 | - Interstitial cell tumor NOS 854 | - Intestinal T-cell lymphoma 855 | - Intestinal-type adenocarcinoma 856 | - Intimal sarcoma 857 | - Intracanalicular fibroadenoma 858 | - Intracortical osteosarcoma 859 | - Intracystic carcinoma NOS 860 | - Intracystic papillary adenocarcinoma 861 | - Intracystic papillary adenoma 862 | - Intracystic papillary neoplasm with associated invasive carcinoma 863 | - Intracystic papillary neoplasm with high grade intraepithelial neoplasia 864 | - Intracystic papillary neoplasm with intermediate grade intraepithelial neoplasia 865 | - Intracystic papillary neoplasm with low grade intraepithelial neoplasia 866 | - Intracystic papillary tumor with high grade dysplasia 867 | - Intracystic papillary tumor with high grade entraepithelial neoplasia 868 | - Intracystic papillary tumor with high grade intraepithelial neoplasia 869 | - Intracystic papilloma 870 | - Intradermal nevus 871 | - Intraductal adenocarcinoma noninfiltrating NOS 872 | - Intraductal and lobular carcinoma 873 | - Intraductal carcinoma and lobular carcinoma in situ 874 | - Intraductal carcinoma clinging 875 | - Intraductal carcinoma noninfiltrating NOS 876 | - Intraductal carcinoma NOS 877 | - Intraductal carcinoma solid type 878 | - Intraductal micropapillary carcinoma 879 | - Intraductal papillary adenocarcinoma with invasion 880 | - Intraductal papillary adenocarcinoma NOS 881 | - Intraductal papillary carcinoma 882 | - Intraductal papillary mucinous neoplasm with an associated invasive carcinoma 883 | - Intraductal papillary mucinous neoplasm with high grade dysplasia 884 | - Intraductal papillary mucinous neoplasm (IPMN) with an associated invasive carcinoma 885 | - Intraductal papillary neoplasm with associated invasive carcinoma 886 | - Intraductal papillary neoplasm with high grade dysplasia 887 | - Intraductal papillary neoplasm with high grade intraepithelial neoplasia 888 | - Intraductal papillary neoplasm with intermediate grade neoplasia 889 | - Intraductal papillary neoplasm with low grade intraepithelial neoplasia 890 | - Intraductal papillary neoplasm NOS 891 | - Intraductal papillary tumor with high grade dysplasia 892 | - Intraductal papillary tumor with high grade intraepithelial neoplasia 893 | - Intraductal papillary-mucinous adenoma 894 | - Intraductal papillary-mucinous carcinoma invasive 895 | - Intraductal papillary-mucinous carcinoma non-invasive 896 | - Intraductal papillary-mucinous neoplasm with low grade dysplasia 897 | - Intraductal papillary-mucinous neoplasm with moderate dysplasia 898 | - Intraductal papillary-mucinous tumor with intermediate dysplasia 899 | - Intraductal papillary-mucinous tumor with low grade dysplasia 900 | - Intraductal papillary-mucinous tumor with moderate dysplasia 901 | - Intraductal papilloma 902 | - Intraductal papilloma with ductal carcinoma in situ 903 | - Intraductal papilloma with lobular carcinoma in situ 904 | - Intraductal papillomatosis NOS 905 | - Intraductal tubular-papillary neoplasm high grade 906 | - Intraductal tubular-papillary neoplasm low grade 907 | - Intraductal tubulopapillary neoplasm 908 | - Intraepidermal carcinoma NOS 909 | - Intraepidermal epithelioma of Jadassohn 910 | - Intraepidermal nevus 911 | - Intraepidermal squamous cell carcinoma Bowen type 912 | - Intraepithelial carcinoma NOS 913 | - Intraepithelial squamous cell carcinoma 914 | - Intraglandular papillary neoplasm with low grade intraepithelial neoplasia 915 | - Intramuscular hemangioma 916 | - Intramuscular lipoma 917 | - Intraneural perineurioma 918 | - Intraosseous low grade osteosarcoma 919 | - Intraosseous well differentiated osteosarcoma 920 | - Intratubular germ cell neoplasia 921 | - Intratubular malignant germ cells 922 | - Intravascular B-cell lymphoma 923 | - Intravascular bronchial alveolar tumor 924 | - Intravascular large B-cell lymphoma 925 | - Intravascular leiomyomatosis 926 | - Invasive carcinoma of no special type 927 | - Invasive carcinoma NST 928 | - Invasive encapsulated follicular variant of papillary thyroid carcinoma (invasive 929 | EFVPTC) 930 | - Invasive fibroma 931 | - Invasive hydatidiform mole 932 | - Invasive lobular carcinoma 933 | - Invasive lobular carcinoma alveolar type 934 | - Invasive lobular carcinoma solid type 935 | - Invasive lobular carcinoma tubulolobular variant 936 | - Invasive mammary carcinoma 937 | - Invasive micropapillary carcinoma 938 | - Invasive mole NOS 939 | - Invasive mucinous adenocarcinoma 940 | - Involuting nevus 941 | - Islet cell adenocarcinoma 942 | - Islet cell adenoma 943 | - Islet cell adenomatosis 944 | - Islet cell carcinoma 945 | - Islet cell tumor benign 946 | - Islet cell tumor NOS 947 | - Jadassohn blue nevus 948 | - Jugular paraganglioma 949 | - Jugulotympanic paraganglioma 950 | - Junction nevus 951 | - Junctional nevus NOS 952 | - Juvenile angiofibroma 953 | - Juvenile astrocytoma 954 | - Juvenile carcinoma of breast 955 | - Juvenile chronic myelomonocytic leukemia 956 | - Juvenile fibroadenoma 957 | - Juvenile hemangioma 958 | - Juvenile histiocytoma 959 | - Juvenile melanoma 960 | - Juvenile myelomonocytic leukemia 961 | - Juvenile nevus 962 | - Juxtacortical chondroma 963 | - Juxtacortical chondrosarcoma 964 | - Juxtacortical osteosarcoma 965 | - Juxtaglomerular tumor 966 | - Kaposi sarcoma 967 | - Kaposiform hemangioendothelioma 968 | - Keratotoc papilloma 969 | - Klatskin tumor 970 | - Krukenberg tumor 971 | - Kupffer cell sarcoma 972 | - L-cell tumor 973 | - Lactating adenoma 974 | - Langerhans cell granulomatosis 975 | - Langerhans cell granulomatosis unifocal 976 | - Langerhans cell histiocytosis disseminated 977 | - Langerhans cell histiocytosis generalized 978 | - Langerhans cell histiocytosis mono-ostotic 979 | - Langerhans cell histiocytosis multifocal 980 | - Langerhans cell histiocytosis NOS 981 | - Langerhans cell histiocytosis poly-ostotic 982 | - Langerhans cell histiocytosis unifocal 983 | - Langerhans cell sarcoma 984 | - Large B-cell lymphoma arising in HHV8-associated multicentric Castleman disease 985 | - Large cell (Ki-1+) lymphoma 986 | - Large cell calcifying Sertoli cell tumor 987 | - Large cell carcinoma with rhabdoid phenotype 988 | - Large cell carcinoma NOS 989 | - Large cell medulloblastoma 990 | - Large cell neuroendocrine carcinoma 991 | - Large granular lymphocytosis NOS 992 | - LCIS NOS 993 | - Leiomyoblastoma 994 | - Leiomyofibroma 995 | - Leiomyoma NOS 996 | - Leiomyomatosis NOS 997 | - Leiomyosarcoma NOS 998 | - Lennert lymphoma 999 | - Lentigo maligna 1000 | - Lentigo maligna melanoma 1001 | - Lepidic adenocarcinoma 1002 | - Lepidic predominant adenocarcinoma 1003 | - Leptomeningeal sarcoma 1004 | - Letterer-Siwe disease 1005 | - Leukemia NOS 1006 | - Leukemic reticuloendotheliosis 1007 | - Leydig cell tumor benign 1008 | - Leydig cell tumor malignant 1009 | - Leydig cell tumor NOS 1010 | - Linitis plastica 1011 | - Lipid cell tumor of ovary 1012 | - Lipid-rich carcinoma 1013 | - Lipid-rich Sertoli cell tumor 1014 | - Lipid-rich urothelial carcinoma 1015 | - Lipoadenoma 1016 | - Lipoblastoma 1017 | - Lipoblastomatosis 1018 | - Lipoid cell tumor of ovary 1019 | - Lipoleiomyoma 1020 | - Lipoma-like liposarcoma 1021 | - Lipoma NOS 1022 | - Lipomatous medulloblastoma 1023 | - Liposarcoma differentiated 1024 | - Liposarcoma NOS 1025 | - Liposarcoma well differentiated 1026 | - Liver cell adenoma 1027 | - Liver cell carcinoma 1028 | - Lobular adenocarcinoma 1029 | - Lobular and ductal carcinoma 1030 | - Lobular carcinoma in situ NOS 1031 | - Lobular carcinoma noninfiltrating 1032 | - Lobular carcinoma NOS 1033 | - Localized fibrous tumor 1034 | - Low grade adenosquamous carcinoma 1035 | - Low grade appendiceal mucinous neoplasm 1036 | - Low grade cribriform cystadenocarcinoma (LGCCC) 1037 | - Low-grade central osteosarcoma 1038 | - Low-grade fibromyxoid sarcoma 1039 | - Low-grade intramedullary osteosarcoma 1040 | - Low-grade myofibroblastic sarcoma 1041 | - Low-grade serous carcinoma 1042 | - Luteinoma 1043 | - Luteoma NOS 1044 | - Lymphangioendothelial sarcoma 1045 | - Lymphangioendothelioma malignant 1046 | - Lymphangioendothelioma NOS 1047 | - Lymphangioleiomyomatosis 1048 | - Lymphangioma NOS 1049 | - Lymphangiomyoma 1050 | - Lymphangiomyomatosis 1051 | - Lymphangiosarcoma 1052 | - Lymphatic leukemic NOS 1053 | - Lymphoblastic leukemia NOS 1054 | - Lymphoblastoma 1055 | - Lymphocytic leukemia NOS 1056 | - Lymphoepithelial carcinoma 1057 | - Lymphoepithelioid lymphoma 1058 | - Lymphoepithelioma 1059 | - Lymphoepithelioma-like carcinoma 1060 | - Lymphoid leukemia NOS 1061 | - Lymphoma NOS 1062 | - Lymphomatoid granulomatosis 1063 | - Lymphomatoid papulosis 1064 | - Lymphoplasmacyte-rich meningioma 1065 | - Lymphoproliferative disease NOS 1066 | - Lymphoproliferative disorder NOS 1067 | - Lymphosarcoma cell leukemia 1068 | - Lymphosarcoma diffuse 1069 | - Lymphosarcoma NOS 1070 | - M6A 1071 | - M6B 1072 | - Macrofollicular adenoma 1073 | - Magnocellular nevus 1074 | - Malignancy 1075 | - Malignant chondroid syringoma 1076 | - Malignant cystic nephroma 1077 | - Malignant eccrine spiradenoma 1078 | - Malignant fibrous histiocytoma 1079 | - Malignant fibrous histiocytoma (MFH) of bone 1080 | - Malignant giant cell tumor of soft parts 1081 | - Malignant histiocytosis 1082 | - Malignant hydatidiform mole 1083 | - Malignant lymphoma centroblastic diffuse 1084 | - Malignant lymphoma centroblastic follicular 1085 | - Malignant lymphoma centroblastic NOS 1086 | - Malignant lymphoma centroblasticcentrocytic diffuse 1087 | - Malignant lymphoma centroblasticcentrocytic follicular 1088 | - Malignant lymphoma centroblasticcentrocytic NOS 1089 | - Malignant lymphoma centrocytic 1090 | - Malignant lymphoma cleaved cell NOS 1091 | - Malignant lymphoma convoluted cell 1092 | - Malignant lymphoma diffuse NOS 1093 | - Malignant lymphoma follicle center follicular 1094 | - Malignant lymphoma follicle center NOS 1095 | - Malignant lymphoma follicular NOS 1096 | - Malignant lymphoma histiocytic diffuse 1097 | - Malignant lymphoma histiocytic nodular 1098 | - Malignant lymphoma histiocytic NOS 1099 | - Malignant lymphoma Hodgkin 1100 | - Malignant lymphoma immunoblastic NOS 1101 | - Malignant lymphoma large B-cell diffuse centroblastic NOS 1102 | - Malignant lymphoma large B-cell diffuse immunoblastic NOS 1103 | - Malignant lymphoma large B-cell diffuse NOS 1104 | - Malignant lymphoma large B-cell NOS 1105 | - Malignant lymphoma large cell cleaved and noncleaved 1106 | - Malignant lymphoma large cell cleaved diffuse 1107 | - Malignant lymphoma large cell cleaved NOS 1108 | - Malignant lymphoma large cell diffuse NOS 1109 | - Malignant lymphoma large cell follicular NOS 1110 | - Malignant lymphoma large cell immunoblastic 1111 | - Malignant lymphoma large cell noncleaved diffuse 1112 | - Malignant lymphoma large cell noncleaved follicular 1113 | - Malignant lymphoma large cell noncleaved NOS 1114 | - Malignant lymphoma large cell NOS 1115 | - Malignant lymphoma large cleaved cell follicular 1116 | - Malignant lymphoma large cleaved cell NOS 1117 | - Malignant lymphoma lymphoblastic NOS 1118 | - Malignant lymphoma lymphocytic diffuse NOS 1119 | - Malignant lymphoma lymphocytic intermediate differentiation diffuse 1120 | - Malignant lymphoma lymphocytic intermediate differentiation nodular 1121 | - Malignant lymphoma lymphocytic nodular NOS 1122 | - Malignant lymphoma lymphocytic NOS 1123 | - Malignant lymphoma lymphocytic poorly differentiated diffuse 1124 | - Malignant lymphoma lymphocytic poorly differentiated nodular 1125 | - Malignant lymphoma lymphocytic well differentiated diffuse 1126 | - Malignant lymphoma lymphocytic well differentiated nodular 1127 | - Malignant lymphoma lymphoplasmacytic 1128 | - Malignant lymphoma lymphoplasmacytoid 1129 | - Malignant lymphoma mixed cell type diffuse 1130 | - Malignant lymphoma mixed cell type follicular 1131 | - Malignant lymphoma mixed cell type nodular 1132 | - Malignant lymphoma mixed lymphocytic-histiocytic diffuse 1133 | - Malignant lymphoma mixed lymphocytic-histiocytic nodular 1134 | - Malignant lymphoma mixed small and large cell diffuse 1135 | - Malignant lymphoma mixed small cleaved and large cell follicular 1136 | - Malignant lymphoma nodular NOS 1137 | - Malignant lymphoma non-cleaved cell NOS 1138 | - Malignant lymphoma non-Hodgkin NOS 1139 | - Malignant lymphoma noncleaved cell follicular NOS 1140 | - Malignant lymphoma noncleaved diffuse NOS 1141 | - Malignant lymphoma noncleaved NOS 1142 | - Malignant lymphoma NOS 1143 | - Malignant lymphoma plasmacytoid 1144 | - Malignant lymphoma small B lymphocytic NOS 1145 | - Malignant lymphoma small cell diffuse 1146 | - Malignant lymphoma small cell noncleaved diffuse 1147 | - Malignant lymphoma small cell NOS 1148 | - Malignant lymphoma small cleaved cell diffuse 1149 | - Malignant lymphoma small cleaved cell follicular 1150 | - Malignant lymphoma small cleaved cell NOS 1151 | - Malignant lymphoma small lymphocytic diffuse 1152 | - Malignant lymphoma small lymphocytic NOS 1153 | - Malignant lymphoma small noncleaved Burkitt type 1154 | - Malignant lymphoma undifferentiated cell type NOS 1155 | - Malignant lymphoma undifferentiated cell non-Burkitt 1156 | - Malignant lymphoma undifferentiated Burkitt type 1157 | - Malignant lymphomatous polyposis 1158 | - Malignant mast cell tumor 1159 | - Malignant mastocytoma 1160 | - Malignant mastocytosis 1161 | - Malignant melanoma in congenital melanocytic nevus 1162 | - Malignant melanoma in giant pigmented nevus 1163 | - Malignant melanoma in Hutchinson melanotic freckle 1164 | - Malignant melanoma in junctional nevus 1165 | - Malignant melanoma in precancerous melanosis 1166 | - Malignant melanoma NOS 1167 | - Malignant melanoma regressing 1168 | - Malignant midline reticulosis 1169 | - Malignant mucinous adenofibroma 1170 | - Malignant mucinous cystadenofibroma 1171 | - Malignant multilocular cystic nephroma 1172 | - Malignant myelosclerosis 1173 | - Malignant myoepithelioma 1174 | - Malignant peripheral nerve sheath tumor 1175 | - Malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation 1176 | - Malignant perivascular epithelial cell tumor 1177 | - Malignant reticulosis NOS 1178 | - Malignant rhabdoid tumor 1179 | - Malignant schwannoma with rhabdomyoblastic differentiation 1180 | - Malignant schwannoma NOS 1181 | - Malignant serous adenofibroma 1182 | - Malignant serous cystadenofibroma 1183 | - Malignant tenosynovial giant cell tumor 1184 | - Malignant teratoma anaplastic 1185 | - Malignant teratoma intermediate 1186 | - Malignant teratoma trophoblastic 1187 | - Malignant teratoma undifferentiated 1188 | - Malignant tumor clear cell type 1189 | - Malignant tumor fusiform cell type 1190 | - Malignant tumor giant cell type 1191 | - Malignant tumor small cell type 1192 | - Malignant tumor spindle cell type 1193 | - MALT lymphoma 1194 | - Mammary carcinoma in situ 1195 | - MANEC 1196 | - Mantle cell lymphoma (Includes all variants blastic pleomorphic small cell) 1197 | - Mantle zone lymphoma 1198 | - Marginal zone B-cell lymphoma NOS 1199 | - Marginal zone lymphoma NOS 1200 | - Masculinovoblastoma 1201 | - Mast cell leukaemia 1202 | - Mast cell sarcoma 1203 | - Mast cell tumor NOS 1204 | - Mastocytoma NOS 1205 | - Matrical carcinoma 1206 | - Mature T ALL 1207 | - Mature T-cell lymphoma NOS 1208 | - Mature teratoma 1209 | - Mediastinal (thymic) large B-cell lymphoma 1210 | - Mediterranean lymphoma 1211 | - Medullary adenocarcinoma 1212 | - Medullary carcinoma with amyloid stroma 1213 | - Medullary carcinoma with lymphoid stroma 1214 | - Medullary carcinoma NOS 1215 | - Medullary osteosarcoma 1216 | - Medullocytoma 1217 | - Medulloepithelioma benign 1218 | - Medulloepithelioma NOS 1219 | - Medullomyoblastoma 1220 | - Megakaryocytic leukemia 1221 | - Megakaryocytic myelosclerosis 1222 | - Melanoameloblastoma 1223 | - Melanocytic nevus 1224 | - Melanocytoma eyeball 1225 | - Melanocytoma NOS 1226 | - Melanoma in situ 1227 | - Melanoma malignant of soft parts 1228 | - Melanoma NOS 1229 | - Melanotic medulloblastoma 1230 | - Melanotic MPNST 1231 | - Melanotic neuroectodermal tumor 1232 | - Melanotic neurofibroma 1233 | - Melanotic progonoma 1234 | - Melanotic psammomatous MPNST 1235 | - Melanotic schwannoma 1236 | - Meningeal melanocytoma 1237 | - Meningeal melanoma 1238 | - Meningeal melanomatosis 1239 | - Meningeal sarcoma 1240 | - Meningeal sarcomatosis 1241 | - Meningioma anaplastic 1242 | - Meningioma malignant 1243 | - Meningioma NOS 1244 | - Meningiomatosis NOS 1245 | - Meningothelial meningioma 1246 | - Meningothelial sarcoma 1247 | - Merkel cell carcinoma 1248 | - Merkel cell tumor 1249 | - Mesenchymal chondrosarcoma 1250 | - Mesenchymal tumor malignant 1251 | - Mesenchymoma benign 1252 | - Mesenchymoma malignant 1253 | - Mesenchymoma NOS 1254 | - Mesenteric fibromatosis 1255 | - Mesoblastic nephroma 1256 | - Mesodermal mixed tumor 1257 | - Mesonephric adenocarcinoma 1258 | - Mesonephric adenoma 1259 | - Mesonephric tumor NOS 1260 | - Mesonephroma benign 1261 | - Mesonephroma malignant 1262 | - Mesonephroma NOS 1263 | - Mesothelial papilloma 1264 | - Mesothelioma benign 1265 | - Mesothelioma biphasic malignant 1266 | - Mesothelioma biphasic NOS 1267 | - Mesothelioma malignant 1268 | - Mesothelioma NOS 1269 | - Metanephric adenoma 1270 | - Metaplastic carcinoma of no special type 1271 | - Metaplastic carcinoma with chondroid differentiation 1272 | - Metaplastic carcinoma with osseous differentiation 1273 | - Metaplastic carcinoma with other types mesenchymal differentiation 1274 | - Metaplastic carcinoma NOS 1275 | - Metaplastic meningioma 1276 | - Metastasizing leiomyoma 1277 | - Metastatic signet ring cell carcinoma 1278 | - Metatypical carcinoma 1279 | - MGUS 1280 | - Microcystic adenoma 1281 | - Microcystic adnexal carcinoma 1282 | - Microcystic meningioma 1283 | - Microcystic urothelial carcinoma 1284 | - Microfollicular adenoma NOS 1285 | - Microglioma 1286 | - Micropapillary adenocarcinoma 1287 | - Micropapillary carcinoma NOS 1288 | - Micropapillary serous carcinoma 1289 | - Midline carcinoma of children and young adults with NUT rearrangement 1290 | - Minimally invasive adenocarcinoma mucinous 1291 | - Minimally invasive adenocarcinoma non-mucinous 1292 | - Minimally invasive adenocarcinoma NOS 1293 | - MiT family translocation renal cell carcinoma 1294 | - Mucinous tumor NOS of low malignant potential 1295 | - Mucocarcinoid tumor 1296 | - Mucoepidermoid carcinoma 1297 | - Mucoepidermoid tumor 1298 | - Mucoid adenocarcinoma 1299 | - Mucoid carcinoma 1300 | - Mucoid cell adenocarcinoma 1301 | - Mucoid cell adenoma 1302 | - Mucosal lentiginous melanoma 1303 | - Mucosal-associated lymphoid tissue lymphoma 1304 | - Mucous adenocarcinoma 1305 | - Mucous carcinoma 1306 | - Mullerian adenosarcoma 1307 | - Mullerian mixed tumor 1308 | - Multicentric basal cell carcinoma 1309 | - Multicystic mesothelioma benign 1310 | - Multifocal superficial basal cell carcinoma 1311 | - Multiple adenomatous polyps 1312 | - Multiple endocrine adenomas 1313 | - Multiple hemorrhagic sarcoma 1314 | - Multiple meningiomas 1315 | - Multiple myeloma 1316 | - Multiple neurofibromatosis 1317 | - Mycosis fungoides 1318 | - Myelocytic leukemia NOS 1319 | - Myelodysplastic syndrome with 5q deletion (5q-) syndrome 1320 | - Myelodysplastic syndrome with isolated del (5q) 1321 | - Myelodysplastic syndrome NOS 1322 | - Myelodysplastic syndrome unclassifiable 1323 | - Myelodysplastic/myeloproliferative neoplasm unclassifiable 1324 | - Myelofibrosis as a result of myeloproliferative disease 1325 | - Myelofibrosis with myeloid metaplasia 1326 | - Myelogenous leukemia NOS 1327 | - Myeloid and lymphoid neoplasms with FGFR1 abnormalities 1328 | - Myeloid and lymphoid neoplasms with PDGFRA rearrangement 1329 | - Myeloid leukemia associated with Down Syndrome 1330 | - Myeloid leukemia NOS 1331 | - Myeloid neoplasms with PDGFRB rearrangement 1332 | - Myeloid sarcoma 1333 | - Myelolipoma 1334 | - Myeloma NOS 1335 | - Myelomatosis 1336 | - Myelomonocytic leukemia NOS 1337 | - Myeloproliferative disease NOS 1338 | - Myeloproliferative neoplasm NOS 1339 | - Myelosclerosis with myeloid metaplasia 1340 | - Myloproliferative neoplasm unclassifiable 1341 | - Myoepithelial adenoma 1342 | - Myoepithelial carcinoma 1343 | - Myoepithelial tumor 1344 | - Myoepithelioma 1345 | - Myofibroblastic sarcoma 1346 | - Myofibroblastic tumor NOS 1347 | - Myofibroblastic tumor peribronchial 1348 | - Myofibroblastoma 1349 | - Myofibroma 1350 | - Myofibromatosis 1351 | - Myoma 1352 | - Myosarcoma 1353 | - Myxofibroma NOS 1354 | - Myxoid chondrosarcoma 1355 | - Myxoid fibroma 1356 | - Myxoid leiomyosarcoma 1357 | - Myxoid liposarcoma 1358 | - Myxoinflammatory fibroblastic sarcoma (MIFS) 1359 | - Myxolipoma 1360 | - Myxoliposarcoma 1361 | - Myxoma NOS 1362 | - Myxopapillary ependymoma 1363 | - Myxosarcoma 1364 | - Neoplasm benign 1365 | - Neoplasm malignant 1366 | - Neoplasm malignant uncertain whether primary or metastatic 1367 | - Neoplasm metastatic 1368 | - Neoplasm NOS 1369 | - Neoplasm secondary 1370 | - Neoplasm uncertain whether benign or malignant 1371 | - Neurotropic melanoma malignant 1372 | - Nevus NOS 1373 | - NK-cell large granular lymphocytic leukemia 1374 | - NK/T-cell lymphoma nasal and nasal-type 1375 | - Nodal marginal zone lymphoma 1376 | - Nodular hidradenoma 1377 | - Nodular hidradenoma malignant 1378 | - Nodular melanoma 1379 | - Non-Hodgkin lymphoma NOS 1380 | - Non-lymphocytic leukemia NOS 1381 | - Non-small cell carcinoma 1382 | - Nonchromaffin paraganglioma malignant 1383 | - Nonchromaffin paraganglioma NOS 1384 | - Nonencapsulated sclerosing adenocarcinoma 1385 | - Nonencapsulated sclerosing carcinoma 1386 | - Nonencapsulated sclerosing tumor 1387 | - Noninfiltrating intracystic carcinoma 1388 | - Noninfiltrating intraductal papillary adenocarcinoma 1389 | - Noninfiltrating intraductal papillary carcinoma 1390 | - Noninvasive pancreatobiliary papillary neoplasm with high grade dysplasia 1391 | - Noninvasive pancreatobiliary papillary neoplasm with high grade intraepithelial 1392 | neoplasia 1393 | - Noninvasive pancreatobiliary papillary neoplasm with low grade dysplasia 1394 | - Noninvasive pancreatobiliary papillary neoplasm with low grade intraepithelial 1395 | neoplasia 1396 | - Non-invasive EFVPTC 1397 | - Non-invasive encapsulated follicular variant of papillary thyroid carcinoma (non-invasive 1398 | EFVPTC) 1399 | - Non-invasive follicular thyroid neoplasm with papillary-like nuclear features 1400 | (NIFTP) 1401 | - Non-invasive FTP 1402 | - Non-invasive low grade serous carcinoma 1403 | - Non-invasive mammary carcinoma 1404 | - Nonlipid reticuloendotheliosis 1405 | - Nonpigmented nevus 1406 | - Not Reported 1407 | - NUT carcinoma 1408 | - NUT midline carcinoma 1409 | - Oat cell carcinoma 1410 | - Phyllodes tumor benign 1411 | - Phyllodes tumor borderline 1412 | - Phyllodes tumor malignant 1413 | - Phyllodes tumor NOS 1414 | - Pick tubular adenoma 1415 | - Pigmented adenoma 1416 | - Pigmented basal cell carcinoma 1417 | - Pigmented dermatofibrosarcoma protuberans 1418 | - Pigmented nevus NOS 1419 | - Pigmented schwannoma 1420 | - Pigmented spindle cell nevus of Reed 1421 | - Pilar tumor 1422 | - Pilocytic astrocytoma 1423 | - Piloid astrocytoma 1424 | - Pilomatricoma malignant 1425 | - Pilomatricoma NOS 1426 | - Pilomatrix carcinoma 1427 | - Pilomatrixoma malignant 1428 | - Pilomatrixoma NOS 1429 | - Pilomyxoid astrocytoma 1430 | - PIN III 1431 | - Pindborg tumor 1432 | - Pineal parenchymal tumor of intermediate differentiation 1433 | - Pinealoma 1434 | - Pineoblastoma 1435 | - Pineocytoma 1436 | - Pinkus tumor 1437 | - Pituicytoma 1438 | - Pituitary adenoma NOS 1439 | - Pituitary carcinoma NOS 1440 | - Placental site trophoblastic tumor 1441 | - Plasma cell leukemia 1442 | - Plasma cell myeloma 1443 | - Plasma cell tumor 1444 | - Plasmablastic lymphoma 1445 | - Plasmacytic leukemia 1446 | - Plasmacytic lymphoma 1447 | - Plasmacytoma of bone 1448 | - Plasmacytoma extramedullary 1449 | - Plasmacytoma NOS 1450 | - Pleomorphic adenoma 1451 | - Pleomorphic carcinoma 1452 | - Pleomorphic cell sarcoma 1453 | - Pleomorphic leiomyoma 1454 | - Pleomorphic lipoma 1455 | - Pleomorphic liposarcoma 1456 | - Pleomorphic lobular carcinoma 1457 | - Pleomorphic lobular carcinoma in situ 1458 | - Pleomorphic rhabdomyosarcoma adult type 1459 | - Pleomorphic rhabdomyosarcoma NOS 1460 | - Pleomorphic xanthoastrocytoma 1461 | - Pleuropulmonary blastoma 1462 | - Plexiform fibrohistiocytic tumor 1463 | - Plexiform fibromyxoma 1464 | - Plexiform hemangioma 1465 | - Plexiform leiomyoma 1466 | - Plexiform neurofibroma 1467 | - Plexiform neuroma 1468 | - Plexiform schwannoma 1469 | - PNET NOS 1470 | - Pneumoblastoma 1471 | - Polar spongioblastoma 1472 | - Polycythemia rubra vera 1473 | - Polycythemia vera 1474 | - Polyembryoma 1475 | - Polygonal cell carcinoma 1476 | - Polymorphic post transplant lymphoproliferative disorder 1477 | - Polymorphic reticulosis 1478 | - Polymorphous low grade adenocarcinoma 1479 | - Polypoid adenoma 1480 | - Polyvesicular vitelline tumor 1481 | - Poorly cohesive carcinoma 1482 | - Porocarcinoma 1483 | - Post transplant lymphoproliferative disorder NOS 1484 | - PP/PYY producing tumor 1485 | - PPNET 1486 | - Pre-B ALL 1487 | - Pre-pre-B ALL 1488 | - Pre-T ALL 1489 | - Precancerous melanosis NOS 1490 | - Precursor B-cell lymphoblastic leukemia 1491 | - Precursor B-cell lymphoblastic lymphoma 1492 | - Precursor cell lymphoblastic leukemia NOS 1493 | - Precursor cell lymphoblastic leukemia not phenotyped 1494 | - Precursor cell lymphoblastic lymphoma NOS 1495 | - Precursor T-cell lymphoblastic leukemia 1496 | - Precursor T-cell lymphoblastic lymphoma 1497 | - Preleukemia 1498 | - Preleukemic syndrome 1499 | - Primary amyloidosis 1500 | - Primary cutaneous anaplastic large cell lymphoma 1501 | - Primary cutaneous CD30+ large T-cell lymphoma 1502 | - Primary cutaneous CD30+ T-cell lymphoproliferative disorder 1503 | - Primary cutaneous CD4-positive small/medium T-cell lymphoma 1504 | - Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma 1505 | - Primary cutaneous DLBCL leg type 1506 | - Primary cutaneous follicle centre lymphoma 1507 | - Primary cutaneous gamma-delta T-cell lymphoma 1508 | - Primary cutaneous neuroendocrine carcinoma 1509 | - Primary diffuse large B-cell lymphoma of the CNS 1510 | - Primary effusion lymphoma 1511 | - Primary intraosseous carcinoma 1512 | - Primary myelofibrosis 1513 | - Primary serous papillary carcinoma of peritoneum 1514 | - Primitive neuroectodermal tumor NOS 1515 | - Primitive polar spongioblastoma 1516 | - Pro-B ALL 1517 | - Pro-T ALL 1518 | - Prolactinoma 1519 | - Proliferating trichilemmal cyst 1520 | - Proliferating trichilemmal tumor 1521 | - Proliferative dermal lesion in congenital nevus 1522 | - Proliferative polycythemia 1523 | - Prolymphocytic leukemia B-cell type 1524 | - Prolymphocytic leukemia NOS 1525 | - Prolymphocytic leukemia T-cell type 1526 | - Prostatic intraepithelial neoplasia grade III 1527 | - Protoplasmic astrocytoma 1528 | - Psammomatous meningioma 1529 | - Psammomatous schwannoma 1530 | - Pseudomucinous adenocarcinoma 1531 | - Pseudomucinous cystadenocarcinoma NOS 1532 | - Pseudomucinous cystadenoma borderline malignancy 1533 | - Pseudomucinous cystadenoma NOS 1534 | - Pseudomyxoma peritonei 1535 | - Pseudomyxoma peritonei with unknown primary site 1536 | - Pseudosarcomatous carcinoma 1537 | - PTLD NOS 1538 | - Pulmonary adenomatosis 1539 | - Pulmonary artery intimal sarcoma 1540 | - Pulmonary blastoma 1541 | - Pulmonary myxoid sarcoma with EWSR1-CREB1 translocation 1542 | - Queyrat erythroplasia 1543 | - Racemose hemangioma 1544 | - RAEB 1545 | - RAEB I 1546 | - RAEB II 1547 | - RAEB-T 1548 | - RARS 1549 | - Rathke pouch tumor 1550 | - Recklinghausen disease 1551 | - Refractory anemia 1552 | - Refractory anemia with excess blasts 1553 | - Refractory anemia with excess blasts in transformation 1554 | - Refractory anemia with ring sideroblasts associated with marked thrombocytosis 1555 | - Refractory anemia with ringed sideroblasts 1556 | - Refractory anemia with sideroblasts 1557 | - Refractory anemia without sideroblasts 1558 | - Refractory cytopenia of childhood 1559 | - Refractory cytopenia with multilineage dysplasia 1560 | - Refractory neutropenia 1561 | - Refractory thrombocytopenia 1562 | - Regressing nevus 1563 | - Round cell carcinoma 1564 | - Round cell liposarcoma 1565 | - Round cell osteosarcoma 1566 | - Round cell sarcoma 1567 | - Salivary duct carcinoma 1568 | - SALT lymphoma 1569 | - Sarcoma botryoides 1570 | - Sarcoma NOS 1571 | - Sarcomatoid carcinoma 1572 | - Serotonin producing carcinoid 1573 | - Serous adenocarcinofibroma 1574 | - Serous adenocarcinoma NOS 1575 | - Serous adenofibroma of borderline malignancy 1576 | - Serous adenofibroma NOS 1577 | - Serous borderline tumor-micropapillary variant 1578 | - Serous carcinoma NOS 1579 | - Serous cystadenocarcinofibroma 1580 | - Serous cystadenocarcinoma NOS 1581 | - Serous cystadenofibroma of borderline malignancy 1582 | - Skin appendage adenoma 1583 | - Skin appendage carcinoma 1584 | - Skin appendage tumor benign 1585 | - Skin-associated lymphoid tissue lymphoma 1586 | - Small cell carcinoma pulmonary type 1587 | - Small cell carcinoma fusiform cell 1588 | - Small cell carcinoma hypercalcemic type 1589 | - Small cell carcinoma intermediate cell 1590 | - Small cell carcinoma NOS 1591 | - Small cell neuroendocrine carcinoma 1592 | - Small cell osteosarcoma 1593 | - Small cell sarcoma 1594 | - Small congenital nevus 1595 | - Smooth muscle tumor of uncertain malignant potential 1596 | - Smooth muscle tumor NOS 1597 | - Soft tissue perineurioma 1598 | - Soft tissue sarcoma 1599 | - Soft tissue tumor benign 1600 | - Soft tissue tumor malignant 1601 | - Solid adenocarcinoma with mucin formation 1602 | - Solid and cystic tumor 1603 | - Solid and papillary epithelial neoplasm 1604 | - Solid carcinoma with mucin formation 1605 | - Solid carcinoma NOS 1606 | - Solid papillary carcinoma in situ 1607 | - Solid papillary carcinoma with invasion 1608 | - Solid pseudopapillary carcinoma 1609 | - Solid pseudopapillary tumor 1610 | - Solid teratoma 1611 | - Solitary fibrous tumor 1612 | - Solitary fibrous tumor malignant 1613 | - Solitary fibrous tumor/hemangiopericytoma Grade 1 (CNS) 1614 | - Solitary fibrous tumor/hemangiopericytoma Grade 2 (CNS) 1615 | - Squamotransitional cell carcinoma 1616 | - Squamous carcinoma 1617 | - Squamous cell carcinoma in situ with questionable stromal invasion 1618 | - Squamous cell carcinoma in situ NOS 1619 | - Squamous cell carcinoma with horn formation 1620 | - Squamous cell carcinoma acantholytic 1621 | - Squamous cell carcinoma adenoid 1622 | - Squamous cell carcinoma clear cell type 1623 | - Squamous cell carcinoma HPV-negative 1624 | - Squamous cell carcinoma HPV-positive 1625 | - Squamous cell carcinoma keratinizing NOS 1626 | - Squamous cell carcinoma large cell keratinizing 1627 | - Squamous cell carcinoma large cell nonkeratinizing NOS 1628 | - Squamous cell carcinoma metastatic NOS 1629 | - Squamous cell carcinoma microinvasive 1630 | - Squamous cell carcinoma nonkeratinizing NOS 1631 | - Squamous cell carcinoma NOS 1632 | - Squamous cell carcinoma pseudoglandular 1633 | - Squamous cell carcinoma sarcomatoid 1634 | - Squamous cell carcinoma small cell nonkeratinizing 1635 | - Squamous cell carcinoma spindle cell 1636 | - Squamous cell epithelioma 1637 | - Squamous cell papilloma inverted 1638 | - Squamous cell papilloma NOS 1639 | - Squamous intraepithelial neoplasia grade I 1640 | - Squamous intraepithelial neoplasia grade II 1641 | - Squamous intraepithelial neoplasia grade III 1642 | - Squamous intraepithelial neoplasia high grade 1643 | - Squamous intraepithelial neoplasia low grade 1644 | - Squamous odontogenic tumor 1645 | - Squamous papilloma 1646 | - Squamous papillomatosis 1647 | - Stem cell leukemia 1648 | - Steroid cell tumor malignant 1649 | - Steroid cell tumor NOS 1650 | - Stromal endometriosis 1651 | - Stromal myosis NOS 1652 | - Stromal sarcoma NOS 1653 | - Stromal tumor with minor sex cord elements 1654 | - Stromal tumor benign 1655 | - Stromal tumor NOS 1656 | - Struma ovarii and carcinoid 1657 | - Struma ovarii malignant 1658 | - Struma ovarii NOS 1659 | - Strumal carcinoid 1660 | - Subacute granulocytic leukemia 1661 | - Subacute leukemia NOS 1662 | - Subacute lymphatic leukemia 1663 | - Subacute lymphocytic leukemia 1664 | - Subacute lymphoid leukemia 1665 | - Subacute monocytic leukemia 1666 | - Subacute myelogenous leukemia 1667 | - Subacute myeloid leukemia 1668 | - Subareolar duct papillomatosis 1669 | - Subcutaneous panniculitis-like T-cell lymphoma 1670 | - Subependymal astrocytoma NOS 1671 | - Subependymal giant cell astrocytoma 1672 | - Subependymal glioma 1673 | - Subependymoma 1674 | - Subepidermal nodular fibrosis 1675 | - Superficial spreading adenocarcinoma 1676 | - Superficial spreading melanoma 1677 | - Superficial well differentiated liposarcoma 1678 | - Supratentorial PNET 1679 | - Sweat gland adenocarcinoma 1680 | - Sweat gland adenoma 1681 | - Sweat gland carcinoma 1682 | - Sweat gland tumor benign 1683 | - Sweat gland tumor malignant 1684 | - Sweat gland tumor NOS 1685 | - Sympathetic paraganglioma 1686 | - Sympathicoblastoma 1687 | - Symplastic leiomyoma 1688 | - Syncytial meningioma 1689 | - Synovial sarcoma biphasic 1690 | - Synovial sarcoma epithelioid cell 1691 | - Synovial sarcoma monophasic fibrous 1692 | - Synovial sarcoma NOS 1693 | - Synovial sarcoma spindle cell 1694 | - Synovioma benign 1695 | - Synovioma malignant 1696 | - Synovioma NOS 1697 | - Syringadenoma NOS 1698 | - Syringocystadenoma papilliferum 1699 | - Syringofibroadenoma 1700 | - Syringoma NOS 1701 | - Syringomatous carcinoma 1702 | - Systemic EBV positive T-cell lymphoproliferative disease of childhood 1703 | - Systemic light chain disease 1704 | - Systemic mastocytosis with AHNMD 1705 | - Systemic mastocytosis with associated hematological clonal non-mast cell disorder 1706 | - Systemic tissue mast cell disease 1707 | - T lymphoblastic leukemia/lymphoma 1708 | - T-cell large granular lymphocytic leukemia 1709 | - T-cell large granular lymphocytosis 1710 | - T-cell lymphoma NOS 1711 | - T-cell rich large B-cell lymphoma 1712 | - T-cell rich/histiocyte-rich large B-cell lymphoma 1713 | - T-gamma lymphoproliferative disease 1714 | - T-zone lymphoma 1715 | - T/NK-cell lymphoma 1716 | - Tanycytic ependymoma 1717 | - Telangiectatic osteosarcoma 1718 | - Tenosynovial giant cell tumor 1719 | - Teratoblastoma malignant 1720 | - Teratocarcinoma 1721 | - Teratoid medulloepithelioma 1722 | - Teratoid medulloepithelioma benign 1723 | - Teratoma with malignant transformation 1724 | - Teratoma benign 1725 | - Teratoma differentiated 1726 | - Teratoma malignant NOS 1727 | - Teratoma NOS 1728 | - Terminal duct adenocarcinoma 1729 | - Testicular adenoma 1730 | - Testicular stromal tumor 1731 | - Theca cell tumor 1732 | - Theca cell-granulosa cell tumor 1733 | - Thecoma luteinized 1734 | - Thecoma malignant 1735 | - Thecoma NOS 1736 | - Therapy related myeloid neoplasm 1737 | - Therapy-related acute myeloid leukemia alkylating agent related 1738 | - Therapy-related acute myeloid leukemia epipodophyllotoxin-related 1739 | - Therapy-related acute myeloid leukemia NOS 1740 | - Therapy-related myelodysplastic syndrome alkylating agent related 1741 | - Therapy-related myelodysplastic syndrome epipodophyllotoxin-related 1742 | - Therapy-related myelodysplastic syndrome NOS 1743 | - Thymic carcinoma with adenoid cystic carcinoma-like features 1744 | - Trabecular adenocarcinoma 1745 | - Trabecular adenoma 1746 | - Trabecular carcinoma 1747 | - Traditional serrated adenoma 1748 | - Traditional sessile serrated adenoma 1749 | - Transient abnormal myelopoiesis 1750 | - Transitional carcinoma 1751 | - Transitional cell carcinoma 1752 | - Transitional cell carcinoma in situ 1753 | - Transitional cell carcinoma micropapillary 1754 | - Transitional cell carcinoma sarcomatoid 1755 | - Transitional cell carcinoma spindle cell 1756 | - Transitional cell papilloma benign 1757 | - Transitional cell papilloma inverted benign 1758 | - Transitional cell papilloma inverted NOS 1759 | - Transitional cell papilloma NOS 1760 | - Transitional meningioma 1761 | - Transitional papilloma 1762 | - Transitional papilloma inverted benign 1763 | - Transitional papilloma inverted NOS 1764 | - Trichilemmalcarcinoma 1765 | - Trichilemmocarcinoma 1766 | - Trichilemmoma 1767 | - Trichodiscoma 1768 | - Trichoepithelioma 1769 | - Trichofolliculoma 1770 | - Triton tumor malignant 1771 | - Trophoblastic tumor epithelioid 1772 | - True histiocytic lymphoma 1773 | - Tubular adenocarcinoma 1774 | - Tubular adenoma NOS 1775 | - Tubular androblastoma with lipid storage 1776 | - Tubular androblastoma NOS 1777 | - Tubular carcinoid 1778 | - Tubular carcinoma 1779 | - Tubulocystic renal cell carcinoma 1780 | - Tubulolobular carcinoma 1781 | - Tubulo-papillary adenoma 1782 | - Tubulopapillary adenocarcinoma 1783 | - Tubulovillous adenoma NOS 1784 | - Tumor cells benign 1785 | - Tumor cells malignant 1786 | - Tumor cells NOS 1787 | - Tumor cells uncertain whether benign or malignant 1788 | - Tumor embolus 1789 | - Tumor benign 1790 | - Tumor malignant NOS 1791 | - Tumor metastatic 1792 | - Tumor NOS 1793 | - Tumor secondary 1794 | - Tumorlet benign 1795 | - Tumorlet NOS 1796 | - Turban tumor 1797 | - Typical carcinoid 1798 | - Not Applicable 1799 | significance: required 1800 | Morphology: 1801 | description: Histologic Morphology Code based on International Classification of 1802 | Diseases 10th Edition. 1803 | category: Diagnosis 1804 | type: string 1805 | valid-values: 1806 | - 8000/0 1807 | - 8000/1 1808 | - 8000/3 1809 | - 8000/6 1810 | - 8000/9 1811 | - 8001/0 1812 | - 8001/1 1813 | - 8001/3 1814 | - 8002/3 1815 | - 8003/3 1816 | - 8004/3 1817 | - 8005/0 1818 | - 8005/3 1819 | - 8010/0 1820 | - 8010/2 1821 | - 8010/3 1822 | - 8010/6 1823 | - 8010/9 1824 | - 8011/0 1825 | - 8011/3 1826 | - 8012/3 1827 | - 8013/3 1828 | - 8014/3 1829 | - 8015/3 1830 | - 8020/3 1831 | - 8021/3 1832 | - 8022/3 1833 | - 8023/3 1834 | - 8030/3 1835 | - 8031/3 1836 | - 8032/3 1837 | - 8033/3 1838 | - 8034/3 1839 | - 8035/3 1840 | - 8040/0 1841 | - 8040/1 1842 | - 8041/3 1843 | - 8041/34 1844 | - 8042/3 1845 | - 8043/3 1846 | - 8044/3 1847 | - 8045/3 1848 | - 8046/3 1849 | - 8050/0 1850 | - 8050/2 1851 | - 8050/3 1852 | - 8051/0 1853 | - 8051/3 1854 | - 8052/0 1855 | - 8052/2 1856 | - 8052/3 1857 | - 8053/0 1858 | - 8060/0 1859 | - 8070/2 1860 | - 8070/3 1861 | - 8070/33 1862 | - 8070/6 1863 | - 8071/2 1864 | - 8071/3 1865 | - 8072/3 1866 | - 8073/3 1867 | - 8074/3 1868 | - 8075/3 1869 | - 8076/2 1870 | - 8076/3 1871 | - 8077/0 1872 | - 8077/2 1873 | - 8078/3 1874 | - 8080/2 1875 | - 8081/2 1876 | - 8082/3 1877 | - 8083/3 1878 | - 8084/3 1879 | - 8085/3 1880 | - 8086/3 1881 | - 8090/1 1882 | - 8090/3 1883 | - 8091/3 1884 | - 8092/3 1885 | - 8093/3 1886 | - 8094/3 1887 | - 8095/3 1888 | - 8096/0 1889 | - 8097/3 1890 | - 8098/3 1891 | - 8100/0 1892 | - 8101/0 1893 | - 8102/0 1894 | - 8102/3 1895 | - 8103/0 1896 | - 8110/0 1897 | - 8110/3 1898 | - 8120/0 1899 | - 8120/1 1900 | - 8120/2 1901 | - 8120/3 1902 | - 8121/0 1903 | - 8121/1 1904 | - 8121/3 1905 | - 8122/3 1906 | - 8123/3 1907 | - 8124/3 1908 | - 8130/1 1909 | - 8130/2 1910 | - 8130/3 1911 | - 8131/3 1912 | - 8140/0 1913 | - 8140/1 1914 | - 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9982/3 2923 | - 9983/3 2924 | - 9984/3 2925 | - 9985/3 2926 | - 9986/3 2927 | - 9987/3 2928 | - 9989/3 2929 | - 9991/3 2930 | - 9992/3 2931 | - Unknown 2932 | - Not Reported 2933 | - Not Applicable 2934 | significance: required 2935 | Site of resection or biopsy: 2936 | description: The text term used to describe the anatomic site of origin, of the 2937 | patient's disease. 2938 | category: Diagnosis 2939 | type: string 2940 | valid-values: 2941 | - Abdomen NOS 2942 | - Abdominal esophagus 2943 | - Accessory sinus NOS 2944 | - Acoustic nerve 2945 | - Adrenal gland NOS 2946 | - Ampulla of Vater 2947 | - Anal canal 2948 | - Anterior 2/3 of tongue NOS 2949 | - Anterior floor of mouth 2950 | - Anterior mediastinum 2951 | - Anterior surface of epiglottis 2952 | - Anterior wall of bladder 2953 | - Anterior wall of nasopharynx 2954 | - Anus NOS 2955 | - Aortic body and other paraganglia 2956 | - Appendix 2957 | - Ascending colon 2958 | - Autonomic nervous system NOS 2959 | - Axillary tail of breast 2960 | - Base of tongue NOS 2961 | - Bladder neck 2962 | - Bladder NOS 2963 | - Blood 2964 | - Body of pancreas 2965 | - Body of penis 2966 | - Body of stomach 2967 | - Bone marrow 2968 | - Bone of limb NOS 2969 | - Bone NOS 2970 | - Bones of skull and face and associated joints 2971 | - Border of tongue 2972 | - Brain stem 2973 | - Brain NOS 2974 | - Branchial cleft 2975 | - Breast NOS 2976 | - Broad ligament 2977 | - Cardia NOS 2978 | - Carotid body 2979 | - Cauda equina 2980 | - Cecum 2981 | - Central portion of breast 2982 | - Cerebellum NOS 2983 | - Cerebral meninges 2984 | - Cerebrum 2985 | - Cervical esophagus 2986 | - Cervix uteri 2987 | - Choroid 2988 | - Ciliary body 2989 | - Cloacogenic zone 2990 | - Colon NOS 2991 | - Commissure of lip 2992 | - Conjunctiva 2993 | - Connective 2994 | - subcutaneous and other soft tissues of abdomen 2995 | - Connective 2996 | - subcutaneous and other soft tissues of head 2997 | - face 2998 | - and neck 2999 | - Connective 3000 | - subcutaneous and other soft tissues of lower limb and hip 3001 | - Connective 3002 | - subcutaneous and other soft tissues of pelvis 3003 | - Connective 3004 | - subcutaneous and other soft tissues of thorax 3005 | - Connective 3006 | - subcutaneous and other soft tissues of trunk NOS 3007 | - Connective 3008 | - subcutaneous and other soft tissues of upper limb and shoulder 3009 | - Connective 3010 | - subcutaneous and other soft tissues NOS 3011 | - Cornea NOS 3012 | - Corpus uteri 3013 | - Cortex of adrenal gland 3014 | - Cranial nerve NOS 3015 | - Craniopharyngeal duct 3016 | - Descended testis 3017 | - Descending colon 3018 | - Dome of bladder 3019 | - Dorsal surface of tongue NOS 3020 | - Duodenum 3021 | - Endocervix 3022 | - Endocrine gland NOS 3023 | - Endometrium 3024 | - Epididymis 3025 | - Esophagus NOS 3026 | - Ethmoid sinus 3027 | - Exocervix 3028 | - External ear 3029 | - External lip NOS 3030 | - External lower lip 3031 | - External upper lip 3032 | - Extrahepatic bile duct 3033 | - Eye NOS 3034 | - Eyelid 3035 | - Fallopian tube 3036 | - Female genital tract NOS 3037 | - Floor of mouth NOS 3038 | - Frontal lobe 3039 | - Frontal sinus 3040 | - Fundus of stomach 3041 | - Fundus uteri 3042 | - Gallbladder 3043 | - Gastric antrum 3044 | - Gastrointestinal tract NOS 3045 | - Glans penis 3046 | - Glottis 3047 | - Greater curvature of stomach NOS 3048 | - Gum NOS 3049 | - Hard palate 3050 | - Head of pancreas 3051 | - Head face or neck NOS 3052 | - Heart 3053 | - Hematopoietic system NOS 3054 | - Hepatic flexure of colon 3055 | - Hypopharyngeal aspect of aryepiglottic fold 3056 | - Hypopharynx NOS 3057 | - Ileum 3058 | - Ill-defined sites within respiratory system 3059 | - Intestinal tract NOS 3060 | - Intra-abdominal lymph nodes 3061 | - Intrahepatic bile duct 3062 | - Intrathoracic lymph nodes 3063 | - Islets of Langerhans 3064 | - Isthmus uteri 3065 | - Jejunum 3066 | - Kidney NOS 3067 | - Labium majus 3068 | - Labium minus 3069 | - Lacrimal gland 3070 | - Laryngeal cartilage 3071 | - Larynx NOS 3072 | - Lateral floor of mouth 3073 | - Lateral wall of bladder 3074 | - Lateral wall of nasopharynx 3075 | - Lateral wall of oropharynx 3076 | - Lesser curvature of stomach NOS 3077 | - Lingual tonsil 3078 | - Lip NOS 3079 | - Liver 3080 | - Long bones of lower limb and associated joints 3081 | - Long bones of upper limb 3082 | - scapula and associated joints 3083 | - Lower gum 3084 | - Lower limb NOS 3085 | - Lower lobe 3086 | - lung 3087 | - Lower third of esophagus 3088 | - Lower-inner quadrant of breast 3089 | - Lower-outer quadrant of breast 3090 | - Lung NOS 3091 | - Lymph node NOS 3092 | - Lymph nodes of axilla or arm 3093 | - Lymph nodes of head 3094 | - face and neck 3095 | - Lymph nodes of inguinal region or leg 3096 | - Lymph nodes of multiple regions 3097 | - Main bronchus 3098 | - Major salivary gland NOS 3099 | - Male genital organs NOS 3100 | - Mandible 3101 | - Maxillary sinus 3102 | - Meckel diverticulum 3103 | - Mediastinum NOS 3104 | - Medulla of adrenal gland 3105 | - Meninges NOS 3106 | - Middle ear 3107 | - Middle lobe 3108 | - lung 3109 | - Middle third of esophagus 3110 | - Mouth NOS 3111 | - Mucosa of lip NOS 3112 | - Mucosa of lower lip 3113 | - Mucosa of upper lip 3114 | - Myometrium 3115 | - Nasal cavity 3116 | - Nasopharynx NOS 3117 | - Nervous system NOS 3118 | - Nipple 3119 | - Occipital lobe 3120 | - Olfactory nerve 3121 | - Optic nerve 3122 | - Orbit NOS 3123 | - Oropharynx NOS 3124 | - Other ill-defined sites 3125 | - Other specified parts of female genital organs 3126 | - Other specified parts of male genital organs 3127 | - Other specified parts of pancreas 3128 | - Ovary 3129 | - Overlapping lesion of accessory sinuses 3130 | - Overlapping lesion of bladder 3131 | - Overlapping lesion of bones 3132 | - joints and articular cartilage 3133 | - Overlapping lesion of bones 3134 | - joints and articular cartilage of limbs 3135 | - Overlapping lesion of brain 3136 | - Overlapping lesion of brain and central nervous system 3137 | - Overlapping lesion of breast 3138 | - Overlapping lesion of cervix uteri 3139 | - Overlapping lesion of colon 3140 | - Overlapping lesion of connective 3141 | - subcutaneous and other soft tissues 3142 | - Overlapping lesion of corpus uteri 3143 | - Overlapping lesion of digestive system 3144 | - Overlapping lesion of endocrine glands and related structures 3145 | - Overlapping lesion of esophagus 3146 | - Overlapping lesion of eye and adnexa 3147 | - Overlapping lesion of female genital organs 3148 | - Overlapping lesion of floor of mouth 3149 | - Overlapping lesion of heart 3150 | - mediastinum and pleura 3151 | - Overlapping lesion of hypopharynx 3152 | - Overlapping lesion of ill-defined sites 3153 | - Overlapping lesion of larynx 3154 | - Overlapping lesion of lip 3155 | - Overlapping lesion of lip 3156 | - oral cavity and pharynx 3157 | - Overlapping lesion of lung 3158 | - Overlapping lesion of major salivary glands 3159 | - Overlapping lesion of male genital organs 3160 | - Overlapping lesion of nasopharynx 3161 | - Overlapping lesion of other and unspecified parts of mouth 3162 | - Overlapping lesion of palate 3163 | - Overlapping lesion of pancreas 3164 | - Overlapping lesion of penis 3165 | - Overlapping lesion of peripheral nerves and autonomic nervous system 3166 | - Overlapping lesion of rectum 3167 | - anus and anal canal 3168 | - Overlapping lesion of respiratory system and intrathoracic organs 3169 | - Overlapping lesion of retroperitoneum and peritoneum 3170 | - Overlapping lesion of skin 3171 | - Overlapping lesion of small intestine 3172 | - Overlapping lesion of stomach 3173 | - Overlapping lesion of tongue 3174 | - Overlapping lesion of tonsil 3175 | - Overlapping lesion of urinary organs 3176 | - Overlapping lesion of vulva 3177 | - Overlapping lesions of oropharynx 3178 | - Palate NOS 3179 | - Pancreas NOS 3180 | - Pancreatic duct 3181 | - Parametrium 3182 | - Parathyroid gland 3183 | - Paraurethral gland 3184 | - Parietal lobe 3185 | - Parotid gland 3186 | - Pelvic bones 3187 | - sacrum 3188 | - coccyx and associated joints 3189 | - Pelvic lymph nodes 3190 | - Pelvis NOS 3191 | - Penis NOS 3192 | - Peripheral nerves and autonomic nervous system of abdomen 3193 | - Peripheral nerves and autonomic nervous system of head 3194 | - face 3195 | - and neck 3196 | - Peripheral nerves and autonomic nervous system of lower limb and hip 3197 | - Peripheral nerves and autonomic nervous system of pelvis 3198 | - Peripheral nerves and autonomic nervous system of thorax 3199 | - Peripheral nerves and autonomic nervous system of trunk NOS 3200 | - Peripheral nerves and autonomic nervous system of upper limb and shoulder 3201 | - Peritoneum NOS 3202 | - Pharynx NOS 3203 | - Pineal gland 3204 | - Pituitary gland 3205 | - Placenta 3206 | - Pleura NOS 3207 | - Postcricoid region 3208 | - Posterior mediastinum 3209 | - Posterior wall of bladder 3210 | - Posterior wall of hypopharynx 3211 | - Posterior wall of nasopharynx 3212 | - Posterior wall of oropharynx 3213 | - Prepuce 3214 | - Prostate gland 3215 | - Pylorus 3216 | - Pyriform sinus 3217 | - Rectosigmoid junction 3218 | - Rectum NOS 3219 | - Renal pelvis 3220 | - Reticuloendothelial system NOS 3221 | - Retina 3222 | - Retromolar area 3223 | - Retroperitoneum 3224 | - Rib 3225 | - sternum 3226 | - clavicle and associated joints 3227 | - Round ligament 3228 | - Scrotum NOS 3229 | - Short bones of lower limb and associated joints 3230 | - Short bones of upper limb and associated joints 3231 | - Sigmoid colon 3232 | - Skin of lip NOS 3233 | - Skin of lower limb and hip 3234 | - Skin of other and unspecified parts of face 3235 | - Skin of scalp and neck 3236 | - Skin of trunk 3237 | - Skin of upper limb and shoulder 3238 | - Skin NOS 3239 | - Small intestine NOS 3240 | - Soft palate NOS 3241 | - Specified parts of peritoneum 3242 | - Spermatic cord 3243 | - Sphenoid sinus 3244 | - Spinal cord 3245 | - Spinal meninges 3246 | - Spleen 3247 | - Splenic flexure of colon 3248 | - Stomach NOS 3249 | - Subglottis 3250 | - Sublingual gland 3251 | - Submandibular gland 3252 | - Superior wall of nasopharynx 3253 | - Supraglottis 3254 | - Tail of pancreas 3255 | - Temporal lobe 3256 | - Testis NOS 3257 | - Thoracic esophagus 3258 | - Thorax NOS 3259 | - Thymus 3260 | - Thyroid gland 3261 | - Tongue NOS 3262 | - Tonsil NOS 3263 | - Tonsillar fossa 3264 | - Tonsillar pillar 3265 | - Trachea 3266 | - Transverse colon 3267 | - Trigone of bladder 3268 | - Undescended testis 3269 | - Unknown primary site 3270 | - Upper Gum 3271 | - Upper limb NOS 3272 | - Upper lobe 3273 | - lung 3274 | - Upper respiratory tract NOS 3275 | - Upper third of esophagus 3276 | - Upper-inner quadrant of breast 3277 | - Upper-outer quadrant of breast 3278 | - Urachus 3279 | - Ureter 3280 | - Ureteric orifice 3281 | - Urethra 3282 | - Urinary system NOS 3283 | - Uterine adnexa 3284 | - Uterus NOS 3285 | - Uvula 3286 | - Vagina NOS 3287 | - Vallecula 3288 | - Ventral surface of tongue NOS 3289 | - Ventricle NOS 3290 | - Vertebral column 3291 | - Vestibule of mouth 3292 | - Vulva NOS 3293 | - Waldeyer ring 3294 | - Biliary tract NOS 3295 | - Cheek mucosa 3296 | - Clitoris 3297 | - Overlapping lesion of biliary tract 3298 | - Unknown 3299 | - Not Reported 3300 | - Not Applicable 3301 | significance: required 3302 | Tissue or organ of origin: 3303 | description: The text term used to describe the anatomic site of origin, of the 3304 | patient's disease. 3305 | category: Diagnosis 3306 | type: string 3307 | valid-values: 3308 | - Abdomen NOS 3309 | - Abdominal esophagus 3310 | - Accessory sinus NOS 3311 | - Acoustic nerve 3312 | - Adrenal gland NOS 3313 | - Ampulla of Vater 3314 | - Anal canal 3315 | - Anterior 2/3 of tongue NOS 3316 | - Anterior floor of mouth 3317 | - Anterior mediastinum 3318 | - Anterior surface of epiglottis 3319 | - Anterior wall of bladder 3320 | - Anterior wall of nasopharynx 3321 | - Anus NOS 3322 | - Aortic body and other paraganglia 3323 | - Appendix 3324 | - Ascending colon 3325 | - Autonomic nervous system NOS 3326 | - Axillary tail of breast 3327 | - Base of tongue NOS 3328 | - Bladder neck 3329 | - Bladder NOS 3330 | - Blood 3331 | - Body of pancreas 3332 | - Body of penis 3333 | - Body of stomach 3334 | - Bone marrow 3335 | - Bone of limb NOS 3336 | - Bone NOS 3337 | - Bones of skull and face and associated joints 3338 | - Border of tongue 3339 | - Brain stem 3340 | - Brain NOS 3341 | - Branchial cleft 3342 | - Breast NOS 3343 | - Broad ligament 3344 | - Cardia NOS 3345 | - Carotid body 3346 | - Cauda equina 3347 | - Cecum 3348 | - Central portion of breast 3349 | - Cerebellum NOS 3350 | - Cerebral meninges 3351 | - Cerebrum 3352 | - Cervical esophagus 3353 | - Cervix uteri 3354 | - Choroid 3355 | - Ciliary body 3356 | - Cloacogenic zone 3357 | - Colon NOS 3358 | - Commissure of lip 3359 | - Conjunctiva 3360 | - Connective 3361 | - subcutaneous and other soft tissues of abdomen 3362 | - Connective 3363 | - subcutaneous and other soft tissues of head 3364 | - face 3365 | - and neck 3366 | - Connective 3367 | - subcutaneous and other soft tissues of lower limb and hip 3368 | - Connective 3369 | - subcutaneous and other soft tissues of pelvis 3370 | - Connective 3371 | - subcutaneous and other soft tissues of thorax 3372 | - Connective 3373 | - subcutaneous and other soft tissues of trunk NOS 3374 | - Connective 3375 | - subcutaneous and other soft tissues of upper limb and shoulder 3376 | - Connective 3377 | - subcutaneous and other soft tissues NOS 3378 | - Cornea NOS 3379 | - Corpus uteri 3380 | - Cortex of adrenal gland 3381 | - Cranial nerve NOS 3382 | - Craniopharyngeal duct 3383 | - Descended testis 3384 | - Descending colon 3385 | - Dome of bladder 3386 | - Dorsal surface of tongue NOS 3387 | - Duodenum 3388 | - Endocervix 3389 | - Endocrine gland NOS 3390 | - Endometrium 3391 | - Epididymis 3392 | - Esophagus NOS 3393 | - Ethmoid sinus 3394 | - Exocervix 3395 | - External ear 3396 | - External lip NOS 3397 | - External lower lip 3398 | - External upper lip 3399 | - Extrahepatic bile duct 3400 | - Eye NOS 3401 | - Eyelid 3402 | - Fallopian tube 3403 | - Female genital tract NOS 3404 | - Floor of mouth NOS 3405 | - Frontal lobe 3406 | - Frontal sinus 3407 | - Fundus of stomach 3408 | - Fundus uteri 3409 | - Gallbladder 3410 | - Gastric antrum 3411 | - Gastrointestinal tract NOS 3412 | - Glans penis 3413 | - Glottis 3414 | - Greater curvature of stomach NOS 3415 | - Gum NOS 3416 | - Hard palate 3417 | - Head of pancreas 3418 | - Head face or neck NOS 3419 | - Heart 3420 | - Hematopoietic system NOS 3421 | - Hepatic flexure of colon 3422 | - Hypopharyngeal aspect of aryepiglottic fold 3423 | - Hypopharynx NOS 3424 | - Ileum 3425 | - Ill-defined sites within respiratory system 3426 | - Intestinal tract NOS 3427 | - Intra-abdominal lymph nodes 3428 | - Intrahepatic bile duct 3429 | - Intrathoracic lymph nodes 3430 | - Islets of Langerhans 3431 | - Isthmus uteri 3432 | - Jejunum 3433 | - Kidney NOS 3434 | - Labium majus 3435 | - Labium minus 3436 | - Lacrimal gland 3437 | - Laryngeal cartilage 3438 | - Larynx NOS 3439 | - Lateral floor of mouth 3440 | - Lateral wall of bladder 3441 | - Lateral wall of nasopharynx 3442 | - Lateral wall of oropharynx 3443 | - Lesser curvature of stomach NOS 3444 | - Lingual tonsil 3445 | - Lip NOS 3446 | - Liver 3447 | - Long bones of lower limb and associated joints 3448 | - Long bones of upper limb 3449 | - scapula and associated joints 3450 | - Lower gum 3451 | - Lower limb NOS 3452 | - Lower lobe 3453 | - lung 3454 | - Lower third of esophagus 3455 | - Lower-inner quadrant of breast 3456 | - Lower-outer quadrant of breast 3457 | - Lung NOS 3458 | - Lymph node NOS 3459 | - Lymph nodes of axilla or arm 3460 | - Lymph nodes of head 3461 | - face and neck 3462 | - Lymph nodes of inguinal region or leg 3463 | - Lymph nodes of multiple regions 3464 | - Main bronchus 3465 | - Major salivary gland NOS 3466 | - Male genital organs NOS 3467 | - Mandible 3468 | - Maxillary sinus 3469 | - Meckel diverticulum 3470 | - Mediastinum NOS 3471 | - Medulla of adrenal gland 3472 | - Meninges NOS 3473 | - Middle ear 3474 | - Middle lobe 3475 | - lung 3476 | - Middle third of esophagus 3477 | - Mouth NOS 3478 | - Mucosa of lip NOS 3479 | - Mucosa of lower lip 3480 | - Mucosa of upper lip 3481 | - Myometrium 3482 | - Nasal cavity 3483 | - Nasopharynx NOS 3484 | - Nervous system NOS 3485 | - Nipple 3486 | - Occipital lobe 3487 | - Olfactory nerve 3488 | - Optic nerve 3489 | - Orbit NOS 3490 | - Oropharynx NOS 3491 | - Other ill-defined sites 3492 | - Other specified parts of female genital organs 3493 | - Other specified parts of male genital organs 3494 | - Other specified parts of pancreas 3495 | - Ovary 3496 | - Overlapping lesion of accessory sinuses 3497 | - Overlapping lesion of bladder 3498 | - Overlapping lesion of bones 3499 | - joints and articular cartilage 3500 | - Overlapping lesion of bones 3501 | - joints and articular cartilage of limbs 3502 | - Overlapping lesion of brain 3503 | - Overlapping lesion of brain and central nervous system 3504 | - Overlapping lesion of breast 3505 | - Overlapping lesion of cervix uteri 3506 | - Overlapping lesion of colon 3507 | - Overlapping lesion of connective 3508 | - subcutaneous and other soft tissues 3509 | - Overlapping lesion of corpus uteri 3510 | - Overlapping lesion of digestive system 3511 | - Overlapping lesion of endocrine glands and related structures 3512 | - Overlapping lesion of esophagus 3513 | - Overlapping lesion of eye and adnexa 3514 | - Overlapping lesion of female genital organs 3515 | - Overlapping lesion of floor of mouth 3516 | - Overlapping lesion of heart 3517 | - mediastinum and pleura 3518 | - Overlapping lesion of hypopharynx 3519 | - Overlapping lesion of ill-defined sites 3520 | - Overlapping lesion of larynx 3521 | - Overlapping lesion of lip 3522 | - Overlapping lesion of lip 3523 | - oral cavity and pharynx 3524 | - Overlapping lesion of lung 3525 | - Overlapping lesion of major salivary glands 3526 | - Overlapping lesion of male genital organs 3527 | - Overlapping lesion of nasopharynx 3528 | - Overlapping lesion of other and unspecified parts of mouth 3529 | - Overlapping lesion of palate 3530 | - Overlapping lesion of pancreas 3531 | - Overlapping lesion of penis 3532 | - Overlapping lesion of peripheral nerves and autonomic nervous system 3533 | - Overlapping lesion of rectum 3534 | - anus and anal canal 3535 | - Overlapping lesion of respiratory system and intrathoracic organs 3536 | - Overlapping lesion of retroperitoneum and peritoneum 3537 | - Overlapping lesion of skin 3538 | - Overlapping lesion of small intestine 3539 | - Overlapping lesion of stomach 3540 | - Overlapping lesion of tongue 3541 | - Overlapping lesion of tonsil 3542 | - Overlapping lesion of urinary organs 3543 | - Overlapping lesion of vulva 3544 | - Overlapping lesions of oropharynx 3545 | - Palate NOS 3546 | - Pancreas NOS 3547 | - Pancreatic duct 3548 | - Parametrium 3549 | - Parathyroid gland 3550 | - Paraurethral gland 3551 | - Parietal lobe 3552 | - Parotid gland 3553 | - Pelvic bones 3554 | - sacrum 3555 | - coccyx and associated joints 3556 | - Pelvic lymph nodes 3557 | - Pelvis NOS 3558 | - Penis NOS 3559 | - Peripheral nerves and autonomic nervous system of abdomen 3560 | - Peripheral nerves and autonomic nervous system of head 3561 | - face 3562 | - and neck 3563 | - Peripheral nerves and autonomic nervous system of lower limb and hip 3564 | - Peripheral nerves and autonomic nervous system of pelvis 3565 | - Peripheral nerves and autonomic nervous system of thorax 3566 | - Peripheral nerves and autonomic nervous system of trunk NOS 3567 | - Peripheral nerves and autonomic nervous system of upper limb and shoulder 3568 | - Peritoneum NOS 3569 | - Pharynx NOS 3570 | - Pineal gland 3571 | - Pituitary gland 3572 | - Placenta 3573 | - Pleura NOS 3574 | - Postcricoid region 3575 | - Posterior mediastinum 3576 | - Posterior wall of bladder 3577 | - Posterior wall of hypopharynx 3578 | - Posterior wall of nasopharynx 3579 | - Posterior wall of oropharynx 3580 | - Prepuce 3581 | - Prostate gland 3582 | - Pylorus 3583 | - Pyriform sinus 3584 | - Rectosigmoid junction 3585 | - Rectum NOS 3586 | - Renal pelvis 3587 | - Reticuloendothelial system NOS 3588 | - Retina 3589 | - Retromolar area 3590 | - Retroperitoneum 3591 | - Rib 3592 | - sternum 3593 | - clavicle and associated joints 3594 | - Round ligament 3595 | - Scrotum NOS 3596 | - Short bones of lower limb and associated joints 3597 | - Short bones of upper limb and associated joints 3598 | - Sigmoid colon 3599 | - Skin of lip NOS 3600 | - Skin of lower limb and hip 3601 | - Skin of other and unspecified parts of face 3602 | - Skin of scalp and neck 3603 | - Skin of trunk 3604 | - Skin of upper limb and shoulder 3605 | - Skin NOS 3606 | - Small intestine NOS 3607 | - Soft palate NOS 3608 | - Specified parts of peritoneum 3609 | - Spermatic cord 3610 | - Sphenoid sinus 3611 | - Spinal cord 3612 | - Spinal meninges 3613 | - Spleen 3614 | - Splenic flexure of colon 3615 | - Stomach NOS 3616 | - Subglottis 3617 | - Sublingual gland 3618 | - Submandibular gland 3619 | - Superior wall of nasopharynx 3620 | - Supraglottis 3621 | - Tail of pancreas 3622 | - Temporal lobe 3623 | - Testis NOS 3624 | - Thoracic esophagus 3625 | - Thorax NOS 3626 | - Thymus 3627 | - Thyroid gland 3628 | - Tongue NOS 3629 | - Tonsil NOS 3630 | - Tonsillar fossa 3631 | - Tonsillar pillar 3632 | - Trachea 3633 | - Transverse colon 3634 | - Trigone of bladder 3635 | - Undescended testis 3636 | - Unknown primary site 3637 | - Upper Gum 3638 | - Upper limb NOS 3639 | - Upper lobe 3640 | - lung 3641 | - Upper respiratory tract NOS 3642 | - Upper third of esophagus 3643 | - Upper-inner quadrant of breast 3644 | - Upper-outer quadrant of breast 3645 | - Urachus 3646 | - Ureter 3647 | - Ureteric orifice 3648 | - Urethra 3649 | - Urinary system NOS 3650 | - Uterine adnexa 3651 | - Uterus NOS 3652 | - Uvula 3653 | - Vagina NOS 3654 | - Vallecula 3655 | - Ventral surface of tongue NOS 3656 | - Ventricle NOS 3657 | - Vertebral column 3658 | - Vestibule of mouth 3659 | - Vulva NOS 3660 | - Waldeyer ring 3661 | - Biliary tract NOS 3662 | - Cheek mucosa 3663 | - Clitoris 3664 | - Overlapping lesion of biliary tract 3665 | - Unknown 3666 | - Not Reported 3667 | - Not Applicable 3668 | significance: required 3669 | Classification of tumor: 3670 | description: Text that describes the kind of disease present in the tumor specimen 3671 | as related to a specific time point. 3672 | category: Diagnosis 3673 | type: string 3674 | valid-values: 3675 | - Primary 3676 | - Metastasis 3677 | - Recurrence 3678 | - Progression 3679 | - Premalignant 3680 | significance: recommended 3681 | Prior treatment: 3682 | description: Yes/no/unknown indicator related to the administration of therapeutic 3683 | agents received before the body specimen was collected. 3684 | category: Diagnosis 3685 | type: string 3686 | valid-values: 3687 | - 'Yes' 3688 | - 'No' 3689 | - Unknown 3690 | significance: recommended 3691 | Days to last follow up: 3692 | description: Time interval from the date of last follow up to the date of initial 3693 | pathologic diagnosis, represented as a calculated number of days. 3694 | category: Diagnosis 3695 | type: integer 3696 | significance: required 3697 | Last known disease status: 3698 | description: Text term that describes the last known state or condition of an individual's 3699 | neoplasm. 3700 | category: Diagnosis 3701 | type: string 3702 | valid-values: 3703 | - Distant met recurrence/progression 3704 | - Loco-regional recurrence/progression 3705 | - Biochemical evidence of disease without structural correlate 3706 | - Tumor free 3707 | - Unknown tumor status 3708 | - With tumor 3709 | significance: required 3710 | Days to last known disease status: 3711 | description: Time interval from the date of last follow up to the date of initial 3712 | pathologic diagnosis, represented as a calculated number of days. 3713 | category: Diagnosis 3714 | type: integer 3715 | significance: required 3716 | Progression or recurrence: 3717 | description: Yes/No/Unknown indicator to identify whether a patient has had a new 3718 | tumor event after initial treatment. 3719 | category: Diagnosis 3720 | type: string 3721 | valid-values: 3722 | - 'Yes' 3723 | - 'No' 3724 | - Unknown 3725 | significance: required 3726 | Days to progression: 3727 | description: Number of days between the date of the patient’s first diagnosis and 3728 | the date the patient's disease progressed. 3729 | category: Diagnosis 3730 | type: integer 3731 | significance: required 3732 | Days to progression free: 3733 | description: Number of days between the date used for index (DOB) and the date the 3734 | patient’s disease was formally confirmed as progression-free. 3735 | category: Diagnosis 3736 | type: integer 3737 | significance: required 3738 | Tumor grade: 3739 | description: Numeric value to express the degree of abnormality of cancer cells, 3740 | a measure of differentiation and aggressiveness. 3741 | category: Diagnosis 3742 | type: string 3743 | valid-values: 3744 | - G1 3745 | - G2 3746 | - G3 3747 | - G4 3748 | - GX 3749 | - GB 3750 | - High Grade 3751 | - Low Grade 3752 | significance: required 3753 | Pack years smoked: 3754 | description: Numeric computed value to represent lifetime tobacco exposure defined 3755 | as number of cigarettes smoked per day x number of years. 3756 | category: Exposures 3757 | type: float 3758 | significance: recommended 3759 | Years smoked: 3760 | description: Numeric value to represent the number of years a person has been smoking. 3761 | category: Exposures 3762 | type: integer 3763 | significance: recommended 3764 | Gene symbol: 3765 | description: 'The text term used to describe a gene targeted or included in molecular 3766 | analysis. For rearrangements, this is should be used to represent the reference 3767 | gene. Note: This node is meant to capture molecular tests that were completed 3768 | clinically for the participant and only includes data from diagnostic array that 3769 | was completed prior to research sequencing was done. Do not include data related 3770 | to research assay outputs here.' 3771 | category: Canonical mutational information 3772 | type: string 3773 | significance: required 3774 | Molecular analysis method: 3775 | description: 'The text term used to describe the method used for molecular analysis. 3776 | Note: This node is meant to capture molecular tests that were completed clinically 3777 | for the participant and only includes data from diagnostic array that was completed 3778 | prior to research sequencing was done. Do not include data related to research 3779 | assay outputs here.' 3780 | category: Canonical mutational information 3781 | type: string 3782 | valid-values: 3783 | - Comparative Genomic Hybridization 3784 | - Cytogenetics NOS 3785 | - FISH 3786 | - Flow Cytometry 3787 | - IHC 3788 | - ISH 3789 | - Karyotype 3790 | - Microarray 3791 | - Microsatellite Analysis 3792 | - Nuclear Staining 3793 | - Other 3794 | - RNA Sequencing 3795 | - RT-PCR 3796 | - Sequencing NOS 3797 | - Southern Blotting 3798 | - Targeted Sequencing 3799 | - WGS 3800 | - WXS 3801 | - Unknown 3802 | - Not Reported 3803 | - Not Applicable 3804 | significance: required 3805 | Test result: 3806 | description: The text term used to describe the result of the molecular test. 3807 | category: Canonical mutational information 3808 | type: string 3809 | valid-values: 3810 | - Abnormal NOS 3811 | - Copy Number Reported 3812 | - Equivocal 3813 | - High 3814 | - Intermediate 3815 | - Loss of Expression 3816 | - Low 3817 | - Negative 3818 | - Normal 3819 | - Overexpressed 3820 | - Positive 3821 | - Test Value Reported 3822 | - Unknown 3823 | - Not Reported 3824 | - Not Applicable 3825 | significance: required 3826 | Treatment type: 3827 | description: Text term that describes the kind of treatment administered. 3828 | category: Treatment 3829 | type: string 3830 | valid-values: 3831 | - Ablation Cryo 3832 | - Ablation Ethanol Injection 3833 | - Ablation Microwave 3834 | - Ablation NOS 3835 | - Ablation Radiofrequency 3836 | - Ablation Radiosurgical 3837 | - Ancillary Treatment 3838 | - Antiseizure Treatment 3839 | - Bisphosphonate Therapy 3840 | - Blinded Study Treatmentunknown 3841 | - Brachytherapy High Dose 3842 | - Brachytherapy Low Dose 3843 | - Brachytherapy NOS 3844 | - Chemoembolization 3845 | - Chemoprotectant 3846 | - Chemotherapy 3847 | - Concurrent Chemoradiation 3848 | - Cryoablation 3849 | - Embolization 3850 | - Ethanol Injection Ablation 3851 | - External Beam Radiation 3852 | - Hormone Therapy 3853 | - I-131 Radiation Therapy 3854 | - Internal Radiation 3855 | - Immunotherapy (Including Vaccines) 3856 | - Isolated Limb Perfusion (ILP) 3857 | - Organ Transplantation 3858 | - Other 3859 | - Pharmaceutical Therapy NOS 3860 | - Pleurodesis 3861 | - Radiation 2D Conventional 3862 | - Radiation 3D Conformal 3863 | - Radiation Combination 3864 | - Radiation Cyberknife 3865 | - Radiation External Beam 3866 | - Radiation Implants 3867 | - Radiation Intensity-Modulated Radiotherapy 3868 | - Radiation Internal 3869 | - Radiation Proton Beam 3870 | - Radiation Radioisotope 3871 | - Radiation Stereotactic/Gamma Knife/SRS 3872 | - Radiation Systemic 3873 | - Radiation Therapy NOS 3874 | - Radioactive Iodine Therapy 3875 | - Radioembolization 3876 | - Radiosensitizing Agent 3877 | - Stem Cell Treatment 3878 | - Stem Cell Transplantation Autologous 3879 | - Stem Cell Transplantation Double Autologous 3880 | - Stem Cell Transplantation Allogeneic 3881 | - Stem Cell Transplantation Non-Myeloablative 3882 | - Stem Cell Transplantation Syngenic 3883 | - Stem Cell TransplantationHaploidentical 3884 | - Stem Cell Transplantation NOS 3885 | - Stereotactic Radiosurgery 3886 | - Steroid Therapy 3887 | - Surgery 3888 | - Targeted Molecular Therapy 3889 | - Unknown 3890 | - Not Reported 3891 | significance: required 3892 | Initial disease status: 3893 | description: Text term used to describe the status of the patient’s malignancy when 3894 | the treatment began. 3895 | category: Treatment 3896 | type: string 3897 | valid-values: 3898 | - Initial Diagnosis 3899 | - Progressive Disease 3900 | - Recurrent Disease 3901 | - Residual Disease 3902 | significance: recommended 3903 | Therapeutic agents: 3904 | description: Text identification of the individual agents used as part of a treatment 3905 | regimen. 3906 | category: Treatment 3907 | type: string 3908 | significance: required 3909 | Days to follow up: 3910 | description: Number of days between the date of sample acquisition and the date 3911 | of the patient's last follow-up appointment or contact. 3912 | category: Follow-Up 3913 | type: float 3914 | significance: recommended 3915 | Lost to follow up: 3916 | description: Yes/No/Unknown indicator to identify whether a patient was lost to 3917 | follow up. 3918 | category: Follow-Up 3919 | type: string 3920 | valid-values: 3921 | - 'Yes' 3922 | - 'No' 3923 | - Unknown 3924 | significance: recommended 3925 | -------------------------------------------------------------------------------- /yaml/02-biospecimen.yaml: -------------------------------------------------------------------------------- 1 | Biospecimen ID: 2 | description: Identifier for the Biospecimen 3 | type: string 4 | significance: required 5 | Parent ID: 6 | description: Parent Identifier from which the biospecimen was obtained. The parent 7 | could be another biospecimen or a research participant. 8 | type: string 9 | significance: required 10 | Adjacent Biospecimen ID: 11 | description: List of Identifiers (separated by commas) of adjacent biospecimens 12 | cut from the same sample 13 | type: string 14 | significance: required 15 | Biospecimen Type: 16 | description: Biospecimen Type 17 | type: string 18 | valid-values: 19 | - Tissue 20 | - Bone Marrow 21 | - Cell Block 22 | - Blood 23 | - Fluids 24 | significance: required 25 | Analyte Type: 26 | description: Text term that represents the kind of molecular specimen analyte. 27 | type: string 28 | significance: required 29 | Protocol Link: 30 | description: Identifier that describes the protocol by which the sample was obtained 31 | or generated. E.g. Protocols.io 32 | category: Collection and Processing 33 | type: doi 34 | significance: required 35 | Timepoint Label: 36 | description: Label to identify the time point at which the biospecimen was obtained. 37 | category: Collection and Processing 38 | type: string 39 | valid-values: 40 | - Baseline 41 | - End of Treatment 42 | - Overall survival 43 | - Final 44 | significance: required 45 | Collection Days From Index: 46 | description: Number of days from the research participant's index date that the 47 | biospecimen was obtained. 48 | category: Collection and Processing 49 | type: float 50 | significance: required 51 | Acquisition Method Type: 52 | description: Records the method of acquisition or source for the specimen under 53 | consideration. 54 | category: Collection and Processing 55 | type: string 56 | valid-values: 57 | - Autopsy 58 | - Biopsy 59 | - Fine needle aspirate 60 | - Surgical Resection 61 | - Punch biopsy 62 | - Shave biopsy 63 | - Excision 64 | - Re-excision 65 | - Sentinel node biopsy 66 | - Lymphadenectomy 67 | significance: required 68 | Post-mortem Interval: 69 | description: Number of days from the research participant's date of death that the 70 | biospecimen was obtained 71 | category: Collection and Processing 72 | type: float 73 | significance: required 74 | Tumor tissue type: 75 | description: Text that describes the kind of disease present in the tumor specimen 76 | as related to a specific time point. 77 | category: Collection and Processing 78 | type: string 79 | valid-values: 80 | - Primary Tumor 81 | - Local Tumor Recurrence 82 | - Distant Tumor Recurrence 83 | - Metastatic 84 | - Premalignant 85 | significance: required 86 | Preservation method: 87 | description: Text term that represents the method used to preserve the sample. 88 | category: Collection and Processing 89 | type: string 90 | valid-values: 91 | - Formaldehyde fixed paraffin embedded (FFPE) 92 | - Frozen 93 | significance: required 94 | Fixative Type: 95 | description: The field to identify the type of fixative used to preserve a tissue 96 | specimen 97 | category: Collection and Processing 98 | type: string 99 | significance: required 100 | Fixation Duration: 101 | description: The length of time, from beginning to end, required to process or preserve 102 | biospecimens in fixative (measured in minutes) 103 | category: Collection and Processing 104 | type: integer 105 | significance: required 106 | Slide Charge Type: 107 | description: A description of the charge on the glass slide. 108 | category: Collection and Processing 109 | type: string 110 | valid-values: 111 | - Uncharged 112 | - Charged 113 | - Coverslip 114 | - Coated 115 | - Not applicable 116 | significance: required 117 | Section Thickness Value: 118 | description: Numeric value to describe the thickness of a slice to tissue taken 119 | from a biospecimen, measured in microns (um). 120 | category: Collection and Processing 121 | type: float 122 | significance: required 123 | Days to sectioning: 124 | description: Number of days between the date of sample acquisition and the date 125 | that the specimen was sectioned 126 | category: Collection and Processing 127 | type: float 128 | significance: required 129 | Storage Method: 130 | description: The method by which a biomaterial was stored after preservation or 131 | before another protocol was used. 132 | category: Collection and Processing 133 | type: string 134 | valid-values: 135 | - Ambient temperature 136 | - 4C 137 | - -20C 138 | - -80C 139 | significance: required 140 | Days to processing: 141 | description: Number of days between the date of sample acquisition and the date 142 | that the biospecimen was processed 143 | category: Collection and Processing 144 | type: float 145 | significance: required 146 | Shipping Conditions: 147 | description: Text descriptor of the shipping environment of a biospecimen. 148 | category: Collection and Processing 149 | type: string 150 | valid-values: 151 | - Ambient Pack 152 | - Cold Pack 153 | - Dry Ice 154 | - Ice Pack 155 | - Liquid Nitrogen 156 | - Other Shipping Environment 157 | - Specimen at Room Temperature 158 | - Not shipped 159 | significance: required 160 | Histology Assessments By: 161 | description: Text term describing who made the histological assessments of the sample 162 | category: Histologic Assessment 163 | type: string 164 | valid-values: 165 | - Pathologist 166 | - Research Scientist 167 | - Other 168 | - Unknown 169 | significance: required 170 | Histology Assessment Medium: 171 | description: The method of assessment used to characterize histology 172 | category: Histologic Assessment 173 | type: string 174 | valid-values: 175 | - Digital 176 | - Microscope 177 | significance: recommended 178 | Tumor infiltrating lymphocytes: 179 | description: Number of tumor-infiltrating lymphocytes 180 | category: Histologic Assessment 181 | type: integer 182 | significance: recommended 183 | Degree of dysplasia: 184 | description: Information related to the presence of cells that look abnormal under 185 | a microscope but are not cancer. Records the degree of dysplasia for the cyst 186 | or lesion under consideration. 187 | category: Histologic Assessment 188 | type: string 189 | valid-values: 190 | - Normal 191 | - basal cell hyperplasia 192 | - or metaplasia Mild dysplasia 193 | - Moderate dysplasia 194 | - Severe dysplasia 195 | - Carcinoma in Situ 196 | significance: recommended 197 | Dysplasia fraction: 198 | description: Information related to the presence of cells that look abnormal under 199 | a microscope but are not cancer. Records the degree of dysplasia for the cyst 200 | or lesion under consideration. 201 | category: Histologic Assessment 202 | type: float 203 | significance: recommended 204 | Number proliferating cells: 205 | description: Numeric value that represents the count of proliferating cells determined 206 | during pathologic review of the sample slide(s). 207 | category: Histologic Assessment 208 | type: integer 209 | significance: recommended 210 | Percent Necrosis: 211 | description: Numeric value to represent the percentage of cell death in a malignant 212 | tumor sample or specimen. 213 | category: Histologic Assessment 214 | type: float 215 | significance: recommended 216 | Percent Normal Cells: 217 | description: Numeric value to represent the percentage of normal cell content in 218 | a malignant tumor sample or specimen. 219 | category: Histologic Assessment 220 | type: float 221 | significance: recommended 222 | Percent Stromal Cells: 223 | description: Numeric value to represent the percentage of reactive cells that are 224 | present in a malignant tumor sample or specimen but are not malignant such as 225 | fibroblasts, vascular structures, etc. 226 | category: Histologic Assessment 227 | type: float 228 | significance: recommended 229 | Percent Tumor Cells: 230 | description: Numeric value to represent the percentage of infiltration by tumor 231 | cells in a sample. 232 | category: Histologic Assessment 233 | type: float 234 | significance: recommended 235 | Percent Tumor Nuclei: 236 | description: Numeric value to represent the percentage of tumor nuclei in a malignant 237 | neoplasm sample or specimen. 238 | category: Histologic Assessment 239 | type: float 240 | significance: recommended 241 | Fiducial marker: 242 | description: Fiducial markers for the alignment of images taken across multiple 243 | rounds of imaging. 244 | category: Imaging 245 | type: string 246 | valid-values: 247 | - Nuclear Stain (DAPI) 248 | - Fluorescent beads 249 | - Grid slides (hemocytometer) 250 | - Adhesive markers 251 | significance: required (unless n/a) 252 | Mounting medium: 253 | description: The solution in which the specimen is embedded, generally under a cover 254 | glass. It may be liquid, gum or resinous, soluble in water, alcohol or other solvents 255 | and be sealed from the external atmosphere by non-soluble ringing media. 256 | category: Imaging 257 | type: string 258 | valid-values: 259 | - Aqueous (water based) medium 260 | - Non-Aqueous (Solvent) based 261 | - Xylene 262 | - Toluene 263 | - Antifade with DAPI 264 | - Antifade without DAPI 265 | - PBS 266 | significance: recommended 267 | Slicing method: 268 | description: The method by which the tissue was sliced. 269 | category: Imaging 270 | type: string 271 | valid-values: 272 | - Vibratome 273 | - Cryosectioning 274 | - Tissue molds 275 | - Sliding microtome 276 | - Sectioning 277 | significance: recommended 278 | Control: 279 | description: Control tissue / area 280 | category: Imaging 281 | type: string 282 | valid-values: 283 | - Cell line 284 | - tissue 285 | - mutation 286 | - matrix 287 | - metal coating 288 | - fiducials 289 | significance: recommended 290 | -------------------------------------------------------------------------------- /yaml/03-file.yaml: -------------------------------------------------------------------------------- 1 | Data File Id: 2 | description: unique e.g., “self” HTAN ID for data file described by this metadata 3 | type: string 4 | significance: required 5 | Filename: 6 | description: name of data file as submitted to repository 7 | type: filename 8 | significance: required 9 | File Format: 10 | description: format of data file 11 | type: string 12 | valid-values: 13 | - SVS 14 | - OME-TIFF 15 | - CZI 16 | significance: required 17 | Channel-Level Metadata Csv Filename: 18 | description: “companion” CSV file containing channel-level metadata for multi-channel/multi-cyclic 19 | methods 20 | type: filename 21 | significance: required 22 | Imaging modality: 23 | description: imaging technology 24 | type: string 25 | valid-values: 26 | - epifluorescence 27 | - lightsheet 28 | - confocal 29 | - ion beam 30 | - laser ablation 31 | significance: required 32 | Assay Type: 33 | description: method / technology used 34 | type: string 35 | valid-values: 36 | - H&E 37 | - t-CyCIF 38 | - IHC 39 | - mIHC 40 | - MxIF 41 | - SABER 42 | - IMC 43 | - CODEX 44 | - MIBI 45 | significance: required 46 | Protocol Id(S): 47 | description: unique identifier (e.g. protocols.io) -- may be a delimited list of 48 | identifiers 49 | type: doi 50 | significance: required 51 | Acquisition software: 52 | description: method(s) and parameters used for any acquisition/ transformation/ 53 | processing to create this image 54 | type: doi 55 | significance: recommended 56 | Image Acquisition Date: 57 | description: The date of image acquisition 58 | type: date 59 | significance: recommended 60 | Microscope: 61 | description: Microscope type (manufacturer, model, etc) used for this experiment 62 | type: string 63 | significance: recommended 64 | Objective: 65 | description: objective lens used (descriptor or other identifier) 66 | type: string 67 | significance: recommended 68 | Nominal Magnification: 69 | description: nominal optical magnification 70 | type: string 71 | valid-values: 72 | - 10X 73 | - 40X 74 | significance: recommended 75 | Lens NA: 76 | description: lens numerical aperture 77 | type: float 78 | significance: recommended 79 | Working Distance: 80 | description: distance from objective to coverslip 81 | type: float 82 | significance: recommended 83 | Working Distance Unit: 84 | description: default = microns 85 | type: float 86 | significance: recommended 87 | Immersion Medium: 88 | description: the imaging medium affects the working NA of the objective 89 | type: string 90 | valid-values: 91 | - Air 92 | - Water 93 | - Glycerin 94 | - Oil 95 | significance: recommended 96 | Comment: 97 | description: Free text field to use if necessary 98 | type: string 99 | significance: recommended 100 | Frame_ Averaging: 101 | description: Number of frames averaged together (if no averaging, set to 1) 102 | type: integer 103 | valid-values: 104 | min: 1.0 105 | significance: recommended 106 | Fov_Number: 107 | description: Index of FOV (as it pertains to its place in the Experiment) 108 | type: integer 109 | valid-values: 110 | min: 1.0 111 | significance: required 112 | Fov_Sizex: 113 | description: FOV size in X-dimension (micron) 114 | type: float 115 | significance: required 116 | Fov_Sizey: 117 | description: FOV size in Y-dimension (micron) 118 | type: float 119 | significance: required 120 | Pyramid: 121 | description: whether or not image file contains a pyramid stack 122 | type: boolean 123 | significance: required 124 | Z_Stack: 125 | description: whether or not image file contains a Z-stack 126 | type: boolean 127 | significance: required 128 | T_Series: 129 | description: whether or not image file contains a time series 130 | type: boolean 131 | significance: required 132 | -------------------------------------------------------------------------------- /yaml/04-channel.yaml: -------------------------------------------------------------------------------- 1 | Channel ID: 2 | description: this must match the corresponding field in the OME-XML / TIFF header 3 | type: string 4 | significance: required 5 | Channel Name: 6 | description: this must match the corresponding field in the OME-XML / TIFF header 7 | type: string 8 | significance: required 9 | Cycle Number: 10 | description: 'the cycle # in which the co-listed reagent(s) was(were) used' 11 | type: integer 12 | valid-values: 13 | min: 1.0 14 | significance: recommended 15 | 'Sub-Cycle #': 16 | description: 'sub-cycle #' 17 | type: integer 18 | valid-values: 19 | min: 1.0 20 | significance: recommended 21 | Target name: 22 | description: short descriptive name (abbreviation) for this target (antigen) 23 | type: string 24 | significance: required 25 | Antibody Name: 26 | description: short descriptive name for this antibody 27 | type: string 28 | significance: required 29 | RRID identifier: 30 | description: Research Resource Identifier 31 | type: rrid 32 | significance: required 33 | Fluorophore: 34 | description: Fluorescent dye label 35 | type: string 36 | significance: required 37 | Clone: 38 | description: Unique clone identifier 39 | type: string 40 | significance: required 41 | Lot: 42 | description: lot number from vendor 43 | type: string 44 | significance: required 45 | Vendor: 46 | description: Vendor name 47 | type: string 48 | significance: required 49 | 'Catalog #': 50 | description: catalog number from vendor 51 | type: string 52 | significance: required 53 | Excitation wavelength: 54 | description: center/peak of the excitation spectrum (nm) 55 | type: float 56 | significance: recommended 57 | Emission wavelength: 58 | description: center/peak of the emission spectrum (nm) 59 | type: float 60 | significance: recommended 61 | Excitation bandwidth: 62 | description: nominal width of excitation spectrum (nm) 63 | type: float 64 | significance: recommended 65 | Emission bandwidth: 66 | description: nominal width of emission spectrum (nm) 67 | type: float 68 | significance: recommended 69 | 'Metal isotope: Element': 70 | description: Element abbreviation 71 | type: string 72 | significance: required 73 | 'Metal isotope: Mass': 74 | description: Element mass number 75 | type: integer 76 | significance: required 77 | 'Oligo barcode: upper strand': 78 | description: DNA barcode used for labeling 79 | type: string 80 | significance: required 81 | 'Oligo barcode: lower strand': 82 | description: DNA barcode used for labeling 83 | type: string 84 | significance: required 85 | Dilution: 86 | description: Final dilution ratio used in experiment 87 | type: string 88 | significance: recommended 89 | Concentration: 90 | description: Final concentration used in experiment 91 | type: string 92 | significance: recommended 93 | Passed QC: 94 | description: Identify stains that did not pass QC but are included in the dataset. 95 | type: boolean 96 | significance: recommended 97 | QC details: 98 | description: Comment on why QC failed 99 | type: string 100 | significance: recommended 101 | Comment: 102 | description: Free text field to use if necessary 103 | type: string 104 | significance: recommended 105 | -------------------------------------------------------------------------------- /yaml/05-ome-tiff-header.yaml: -------------------------------------------------------------------------------- 1 | Image ID: 2 | description: unique internal Image identifier 3 | type: string 4 | significance: required 5 | Pixels BigEndian: 6 | description: whether big endian byte order is used 7 | type: boolean 8 | significance: required 9 | DimensionOrder: 10 | description: internal ordering of dimensions 11 | type: string 12 | significance: required 13 | PhysicalSizeX: 14 | description: physical size of one pixel in x-dimension 15 | type: float 16 | significance: required 17 | PhysicalSizeXUnit: 18 | description: unit for PhysicalSizeX 19 | type: string 20 | significance: required 21 | PhysicalSizeY: 22 | description: physical size of one pixel in y-dimension 23 | type: float 24 | significance: required 25 | PhysicalSizeYUnit: 26 | description: unit for PhysicalSizeY 27 | type: string 28 | significance: required 29 | PhysicalSizeZ: 30 | description: physical size of one pixel in z-dimension 31 | type: float 32 | significance: 33 | required: SizeZ > 1 34 | PhysicalSizeZUnit: 35 | description: unit for PhysicalSizeZ 36 | type: string 37 | significance: 38 | required: SizeZ > 1 39 | SizeC: 40 | description: number of channels 41 | type: integer 42 | valid-values: 43 | min: 0.0 44 | significance: required 45 | SizeT: 46 | description: number of time-points 47 | type: integer 48 | valid-values: 49 | min: 0.0 50 | significance: required 51 | SizeX: 52 | description: number of pixels in x-dimension 53 | type: integer 54 | valid-values: 55 | min: 0.0 56 | significance: required 57 | SizeY: 58 | description: number of pixels in y-dimension 59 | type: integer 60 | valid-values: 61 | min: 0.0 62 | significance: required 63 | SizeZ: 64 | description: number of z-planes 65 | type: integer 66 | valid-values: 67 | min: 0.0 68 | significance: required 69 | Type: 70 | description: data type for each pixel value 71 | type: string 72 | valid-values: 73 | - uint16 74 | - float 75 | significance: required 76 | PlaneCount: 77 | description: total number of planes in this Image 78 | type: integer 79 | valid-values: 80 | min: 0.0 81 | significance: required 82 | Channel Name: 83 | description: channel label for each channel in this image 84 | type: string 85 | significance: required 86 | Comment: 87 | description: Free text field to use if necessary 88 | type: string 89 | significance: recommended 90 | -------------------------------------------------------------------------------- /yaml/06-processed-data.yaml: -------------------------------------------------------------------------------- 1 | Data Type: 2 | description: Specify if OME-TIFF provided is a segmentation mask or QC-checked image 3 | type: string 4 | significance: required 5 | valid-values: 6 | - mask 7 | - image 8 | Data File ID: 9 | description: unique e.g., “self” HTAN ID for data file described by this metadata 10 | type: string 11 | significance: required 12 | Filename: 13 | description: name of data file as submitted to repository 14 | type: filename 15 | significance: required 16 | File Format: 17 | description: format of data file 18 | type: string 19 | significance: required 20 | Parent Data File ID: 21 | description: HTAN ID of Data File from which this Data File was derived 22 | type: string 23 | significance: recommended 24 | Protocol ID(s): 25 | description: unique identifier (e.g. protocols.io) -- may be a delimited list of 26 | identifiers 27 | type: doi 28 | significance: required 29 | Software and Version: 30 | description: method(s) and parameters used for any quality control, transformation, 31 | and visualization to create this image 32 | type: doi 33 | significance: required 34 | Commit SHA: 35 | description: Short SHA for software version (8 hexadecimal characters for github) 36 | type: string 37 | significance: required 38 | Passed QC: 39 | description: did all masks pass QC 40 | type: boolean 41 | significance: 42 | required: Data type == ‘image’ 43 | Comment: 44 | description: Free text field to use if necessary 45 | type: string 46 | significance: recommended 47 | Object class: 48 | description: Defines if the mask delineates nucleus, the cytoplasm, plasma membrane, the whole cell or other 49 | type: string 50 | significance: 51 | required: Data type == 'mask' 52 | valid-values: 53 | - nuclei 54 | - cytoplasm 55 | - cell 56 | - plasma membrane 57 | - other 58 | Object class Description: 59 | description: Free text description of object class 60 | type: string 61 | significance: 62 | required: Object class == 'other' 63 | Minimum Intensity Display Range: 64 | description: Lower-bound intensity value 65 | type: integer 66 | significance: recommended 67 | Maximum Intensity Display Range: 68 | description: Upper-bound intensity value 69 | type: integer 70 | significance: recommended 71 | FOV_number: 72 | description: Index of FOV (as it pertains to its place in the Experiment) 73 | type: integer 74 | valid-values: 75 | min: 1.0 76 | significance: recommended 77 | FOV_SizeX: 78 | description: FOV size in X-dimension (micron) 79 | type: float 80 | significance: recommended 81 | FOV_SizeY: 82 | description: FOV size in Y-dimension (micron) 83 | type: float 84 | significance: recommended 85 | Pyramid: 86 | description: whether or not image file contains a pyramid stack 87 | type: boolean 88 | significance: recommended 89 | Z_stack: 90 | description: whether or not image file contains a Z-stack 91 | type: boolean 92 | significance: recommended 93 | T_series: 94 | description: whether or not image file contains a time series 95 | type: boolean 96 | significance: recommended 97 | PhysicalSizeX: 98 | description: physical size of one pixel in x-dimension 99 | type: float 100 | significance: required 101 | PhysicalSizeXUnit: 102 | description: unit for PhysicalSizeX 103 | type: string 104 | significance: required 105 | PhysicalSizeY: 106 | description: physical size of one pixel in y-dimension 107 | type: float 108 | significance: required 109 | PhysicalSizeYUnit: 110 | description: unit for PhysicalSizeY 111 | type: string 112 | significance: required 113 | PhysicalSizeZ: 114 | description: physical size of one pixel in z-dimension 115 | type: float 116 | significance: 117 | required: Z_stack == True 118 | PhysicalSizeZUnit: 119 | description: unit for PhysicalSizeZ 120 | type: string 121 | significance: 122 | required: Z_stack == True 123 | Type: 124 | description: data type for each pixel value 125 | type: string 126 | significance: required 127 | -------------------------------------------------------------------------------- /yaml/07-cell.yaml: -------------------------------------------------------------------------------- 1 | Data File ID: 2 | description: unique e.g., “self” HTAN ID for data file described by this metadata 3 | type: string 4 | significance: required 5 | Filename: 6 | description: name of data file as submitted to repository 7 | type: filename 8 | significance: required 9 | File Format: 10 | description: format of data file 11 | type: string 12 | valid-values: 13 | - CSV 14 | - FCS 15 | - H5AD 16 | significance: required 17 | Parent ID: 18 | description: Parent Identifier from which the biospecimen was obtained. The parent 19 | could be another biospecimen or a research participant. 20 | type: string 21 | significance: required 22 | Software and Version: 23 | description: method(s) and parameters used for any acquisition/ transformation/ 24 | processing to create this image 25 | type: doi 26 | significance: required 27 | Commit SHA: 28 | description: Short SHA for software version (8 hexadecimal characters for github) 29 | type: string 30 | significance: required 31 | Comment: 32 | description: Free text field to use if necessary 33 | type: string 34 | significance: recommended 35 | Header size: 36 | description: How many columns do have in the CSV / FCS 37 | type: integer 38 | significance: required 39 | Object classes included: 40 | description: Defines which cell compartment this mask pertains or which tissue structure 41 | type: string 42 | valid-values: 43 | - nuclei 44 | - cytoplasm 45 | - cell 46 | - plasma membrane 47 | - other 48 | significance: required 49 | Object classes description: 50 | description: Free text description of object class 51 | type: string 52 | significance: 53 | required: Object classes included == 'other' 54 | FOV_SizeX: 55 | description: FOV size in X-dimension (micron) 56 | type: float 57 | significance: recommended 58 | FOV_SizeY: 59 | description: FOV size in Y-dimension (micron) 60 | type: float 61 | significance: recommended 62 | Pyramid: 63 | description: whether or not image file contains a pyramid stack 64 | type: boolean 65 | significance: required 66 | Z_stack: 67 | description: whether or not image file contains a Z-stack 68 | type: boolean 69 | significance: required 70 | T_series: 71 | description: whether or not image file contains a time series 72 | type: boolean 73 | significance: required 74 | Type: 75 | description: bit depth of image 76 | type: string 77 | significance: required 78 | PhysicalSizeX: 79 | description: physical size of one pixel in x-dimension 80 | type: float 81 | significance: required 82 | PhysicalSizeXUnit: 83 | description: unit for PhysicalSizeX 84 | type: string 85 | significance: required 86 | PhysicalSizeY: 87 | description: physical size of one pixel in y-dimension 88 | type: float 89 | significance: required 90 | PhysicalSizeYUnit: 91 | description: unit for PhysicalSizeY 92 | type: string 93 | significance: required 94 | PhysicalSizeZ: 95 | description: physical size of one pixel in Z-dimension 96 | type: float 97 | significance: required 98 | PhysicalSizeZUnit: 99 | description: unit for PhysicalSizeZ 100 | type: string 101 | significance: required 102 | Cell-state level: 103 | description: Are cell types / states included? 104 | type: boolean 105 | significance: required 106 | -------------------------------------------------------------------------------- /yaml/08-cell-state.yaml: -------------------------------------------------------------------------------- 1 | Data File ID: 2 | description: unique e.g., “self” HTAN ID for data file described by this metadata 3 | type: string 4 | significance: required 5 | Filename: 6 | description: name of data file as submitted to repository 7 | type: filename 8 | significance: required 9 | File Format: 10 | description: format of data file 11 | type: string 12 | valid-values: 13 | - CSV 14 | - FCS 15 | significance: required 16 | Parent ID: 17 | description: Parent Identifier from which the biospecimen was obtained. The parent 18 | could be another biospecimen or a research participant. 19 | type: string 20 | significance: required 21 | Protocol ID(s): 22 | description: unique identifier (e.g. protocols.io) -- may be a delimited list of 23 | identifiers 24 | type: doi 25 | significance: required 26 | Software and Version: 27 | description: method(s) and parameters used for any acquisition/ transformation/ 28 | processing to create this image 29 | type: doi 30 | significance: required 31 | Comment: 32 | description: Free text field to use if necessary 33 | type: string 34 | significance: recommended 35 | Header size: 36 | description: How many columns do have in the CSV / FCS / hdf5 37 | type: integer 38 | significance: required 39 | Possible cell type / states format: 40 | description: A semicolon-delimited list of possible keywords that each cell will 41 | be annotated with 42 | type: string 43 | significance: recommended 44 | Cell type clustering / calling methods: 45 | description: Methods used (connected to protocols.io) (for example PhenoGraph, k-means, etc.) 46 | type: string 47 | significance: recommended 48 | Algorithm parameters: 49 | description: Description of algorithm parameters 50 | type: string 51 | significance: recommended 52 | --------------------------------------------------------------------------------