├── .gitignore ├── README.md ├── UnitTest.m ├── CalcGamma.m └── LICENSE /.gitignore: -------------------------------------------------------------------------------- 1 | *.smbdelete* 2 | .DS_STORE 3 | *.m~ 4 | log.txt 5 | test_data/ 6 | -------------------------------------------------------------------------------- /README.md: -------------------------------------------------------------------------------- 1 | # CalcGamma 2 | 3 | [![DOI](https://zenodo.org/badge/26833173.svg)](https://zenodo.org/doi/10.5281/zenodo.12735617) 4 | 5 | by Mark Geurts 6 |
Copyright © 2015, University of Wisconsin Board of Regents 7 | 8 | ## Description 9 | 10 | `CalcGamma()` computes a 1-D, 2-D, or 3-D local or global Gamma index between two datasets (reference and target) given a defined coordinate space using MATLAB. The Gamma analysis is performed based on the formalism presented by D. A. Low et. al., [A technique for the quantitative evaluation of dose distributions.](http://www.ncbi.nlm.nih.gov/pubmed/9608475), Med Phys. 1998 May; 25(5): 656-61. 11 | 12 | ## Installation 13 | 14 | To install this function, copy `CalcGamma.m` from this repository into your MATLAB path. If installing as a submodule into another git repository, execute `git submodule add https://github.com/mwgeurts/gamma`. 15 | 16 | ## Usage and Documentation 17 | 18 | ```matlab 19 | gamma = CalcGamma(reference, target, percent, dta); 20 | gamma = CalcGamma(..., 'OptionName', OptionValue); 21 | ``` 22 | 23 | See the [wiki](../../wiki) for information on the format of the input and arguments as well options and examples. 24 | 25 | ## License 26 | 27 | Released under the GNU GPL v3.0 License. See the [LICENSE](LICENSE) file for further details. 28 | -------------------------------------------------------------------------------- /UnitTest.m: -------------------------------------------------------------------------------- 1 | function varargout = UnitTest(varargin) 2 | % UnitTest executes the unit tests for this application, and can be called 3 | % either independently (when testing just the latest version) or via 4 | % UnitTestHarness (when testing for regressions between versions). Either 5 | % two or three input arguments can be passed to UnitTest as described 6 | % below. 7 | % 8 | % The following variables are required for proper execution: 9 | % varargin{1}: string containing the path to the main function. This is 10 | % only required if UnitTest is to be operated across multiple file 11 | % names; otherwise it can be an empty string. 12 | % varargin{2}: variable containing the test data. this can be a string 13 | % to a file, a structure, or any MATLAB variable. 14 | % varargin{3} (optional): variable containing reference data to be used 15 | % for comparison. If not provided, it is assumed that this version 16 | % is the reference and therefore all comparison tests will "Pass". 17 | % 18 | % The following variables are returned upon succesful completion when input 19 | % arguments are provided. If no return variables are given, the results 20 | % will be printed to stdout. 21 | % varargout{1}: cell array of strings containing preamble text that 22 | % summarizes the test, where each cell is a line. This text will 23 | % precede the results table in the report. 24 | % varargout{2}: n x 3 cell array of strings containing the test ID in 25 | % the first column, name in the second, and result (Pass/Fail or 26 | % numerical values typically) of the test in the third. 27 | % varargout{3}: cell array of strings containing footnotes referenced by 28 | % the tests, where each cell is a line. This text will follow the 29 | % results table in the report. 30 | % varargout{4} (optional): variable containing reference data created by 31 | % executing this version. This variable can be passed back into 32 | % subsequent executions of UnitTest as varargin{3} to compare results 33 | % between versions (or to a priori validated reference data). 34 | % 35 | % The following variables are returned when no input arguments are 36 | % provided (required only if called by UnitTestHarness): 37 | % varargout{1}: string containing the application name (with .m 38 | % extension) 39 | % varargout{2}: string containing the path to the version application 40 | % whose results will be used as reference 41 | % varargout{3}: 1 x n cell array of strings containing paths to the other 42 | % applications which will be tested 43 | % varargout{4}: 2 x m cell array of strings containing the name of each 44 | % test suite (first column) and path to the test data (second column) 45 | % varargout{5}: string containing the path and name of report file (will 46 | % be appended by _R201XX.md based on the MATLAB version) 47 | % 48 | % Below is an example of how this function is used: 49 | % 50 | % % Start profiler 51 | % profile on -history 52 | % 53 | % % Execute unit test, printing the test results to stdout 54 | % UnitTest('', load('../test_data/InputData.mat'), ... 55 | % load('../test_data/OutputData.mat')); 56 | % 57 | % % Stop and view the profiler results 58 | % profile viewer 59 | % 60 | % % Execute unit test, storing the test results 61 | % [preamble, table, footnotes] = UnitTest('', ... 62 | % load('../test_data/InputData.mat'), ... 63 | % load('../test_data/OutputData.mat')); 64 | % 65 | % % Execute unit test again but without reference data, this time storing 66 | % % the output from UnitTest as a new reference file 67 | % [preamble, table, footnotes, newreference] = ... 68 | % UnitTest('', load('../test_data/InputData.mat')); 69 | % 70 | % Author: Mark Geurts, mark.w.geurts@gmail.com 71 | % Copyright (C) 2015 University of Wisconsin Board of Regents 72 | % 73 | % This program is free software: you can redistribute it and/or modify it 74 | % under the terms of the GNU General Public License as published by the 75 | % Free Software Foundation, either version 3 of the License, or (at your 76 | % option) any later version. 77 | % 78 | % This program is distributed in the hope that it will be useful, but 79 | % WITHOUT ANY WARRANTY; without even the implied warranty of 80 | % MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General 81 | % Public License for more details. 82 | % 83 | % You should have received a copy of the GNU General Public License along 84 | % with this program. If not, see http://www.gnu.org/licenses/. 85 | 86 | %% Return Application Information 87 | % If UnitTest was executed without input arguments 88 | if nargin == 0 89 | 90 | % Declare the application filename 91 | varargout{1} = ''; 92 | 93 | % Declare current version directory 94 | varargout{2} = ''; 95 | 96 | % Declare prior version directories 97 | varargout{3} = {}; 98 | 99 | % Declare location of test data. Column 1 is the name of the 100 | % test suite, column 2 is the absolute path to the file(s) 101 | varargout{4} = {}; 102 | 103 | % Declare name of report file (will be appended by _R201XX.md based on 104 | % the MATLAB version) 105 | varargout{5} = ''; 106 | 107 | % Return to invoking function 108 | return; 109 | end 110 | 111 | %% Initialize Unit Testing 112 | % Initialize static test result text variables 113 | pass = 'Pass'; 114 | fail = 'Fail'; 115 | unk = 'N/A'; %#ok 116 | 117 | % Initialize preamble text 118 | preamble = { 119 | '| Input Data | Value |' 120 | '|------------|-------|' 121 | }; 122 | 123 | % Initialize results cell array 124 | results = cell(0,3); 125 | 126 | % Initialize footnotes cell array 127 | footnotes = cell(0,1); 128 | 129 | % Initialize reference structure 130 | if nargout == 4 131 | reference = struct; 132 | end 133 | 134 | %% TEST 1/2/3/4: Analytic 1D Gamma 135 | % 136 | % DESCRIPTION: This unit test creates a large analytic reference dataset, 137 | % modifies it by a known amount, and executes CalcGamma. The gamma 138 | % result is then compared to a known solution 139 | % 140 | % RELEVANT REQUIREMENTS: none 141 | % 142 | % INPUT DATA: varargin{3}.gammaA 143 | % 144 | % CONDITION A (+): When computed using identical criteria, CalcGamma 145 | % produces an identical array to the reference with GPU Calculation 146 | % 147 | % CONDITION B (+): When computed using identical criteria, CalcGamma 148 | % produces an identical array to the reference with CPU Calculation 149 | % 150 | % CONDITION C (-): When computed using modified criteria, CalcGamma 151 | % produces a different result 152 | 153 | % Add path to Event() function (to test Event calls function) 154 | addpath('../test_data/'); 155 | 156 | % Declare gamma criteria 157 | percent = 3; 158 | dta = 0.3; 159 | local = 1; 160 | 161 | % Declare size of data arrays 162 | n = 2000; 163 | 164 | % Create reference structure (sine function) 165 | ref.start = 0; 166 | ref.width = pi / 1000; 167 | ref.data = sin(ref.start:ref.width:... 168 | ref.start + ref.width * n) + 2; 169 | 170 | % Declare modification values (to be applied to target data) 171 | shift = 0.1; 172 | scale = 1.01; 173 | 174 | % Modify reference data, saving to target structure 175 | target.start = ref.start + shift; 176 | target.width = ref.width; 177 | target.data = ref.data * scale; 178 | 179 | % Execute in try/catch statement 180 | try 181 | 182 | % Execute CalcGamma using test dataset 183 | t = tic; 184 | gamma = CalcGamma(ref, target, percent, dta, 'local', local); 185 | gtime = sprintf('%0.1f sec', toc(t)); 186 | gpf = pass; 187 | cpf = pass; 188 | 189 | % If reference data exists 190 | if nargin == 3 191 | 192 | % If current value does not equal the reference 193 | if max(abs(gamma - varargin{3}.gammaA)) > 1e-5 194 | gpf = fail; 195 | end 196 | 197 | % Execute CalcGamma again using CPU 198 | t = tic; 199 | gamma = CalcGamma(ref, target, percent, dta, 'cpu', 1, ... 200 | 'local', local); 201 | ctime = sprintf('%0.1f sec', toc(t)); 202 | 203 | % If CPU value does not equal the reference 204 | if max(abs(gamma - varargin{3}.gammaA)) > 1e-5 205 | cpf = fail; 206 | end 207 | 208 | % Execute CalcGamma again, this time using modified criteria 209 | gamma = CalcGamma(ref, target, percent, dta * 2, ... 210 | 'local', local); 211 | 212 | % If modified value equals the reference, the test fails 213 | if max(abs(gamma - varargin{3}.gammaA)) < 1e-5 214 | gpf = fail; 215 | end 216 | 217 | % Execute CalcGamma again, this time using modified criteria 218 | gamma = CalcGamma(ref, target, percent * 2, dta, ... 219 | 'local', local); 220 | 221 | % If modified value equals the reference, the test fails 222 | if max(abs(gamma - varargin{3}.gammaA)) < 1e-5 223 | gpf = fail; 224 | end 225 | 226 | % Otherwise, set reference 227 | elseif nargout == 4 228 | reference.gammaA = gamma; 229 | gpf = pass; 230 | cpf = pass; 231 | end 232 | 233 | catch 234 | gpf = fail; 235 | cpf = fail; 236 | end 237 | 238 | % Add the dataset size to the preamble 239 | preamble{length(preamble)+1} = ... 240 | sprintf('| Analytic 1D Gamma Array | %i x %i |', size(gamma)); 241 | 242 | % Add header to results table 243 | results{size(results,1)+1,1} = 'ID'; 244 | results{size(results,1),2} = 'Test Case'; 245 | results{size(results,1),3} = 'Result'; 246 | 247 | % Add GPU computation result 248 | results{size(results,1)+1,1} = '1'; 249 | results{size(results,1),2} = 'Analytic 1D Gamma GPU Result within 1e-5'; 250 | results{size(results,1),3} = gpf; 251 | 252 | % Add computation time 253 | results{size(results,1)+1,1} = '2'; 254 | results{size(results,1),2} = 'Analytic 1D Gamma GPU Computation Time'; 255 | results{size(results,1),3} = gtime; 256 | 257 | % Add CPU computation result 258 | results{size(results,1)+1,1} = '3'; 259 | results{size(results,1),2} = 'Analytic 1D Gamma CPU Result within 1e-5'; 260 | results{size(results,1),3} = cpf; 261 | 262 | % Add computation time 263 | results{size(results,1)+1,1} = '4'; 264 | results{size(results,1),2} = 'Analytic 1D Gamma CPU Computation Time'; 265 | results{size(results,1),3} = ctime; 266 | 267 | %% TEST 5/6/7/8: Beam Profile 1D Gamma 268 | % 269 | % DESCRIPTION: This unit test creates a real world profile dataset 270 | % and executes CalcGamma. The gamma result is then compared to a known 271 | % solution 272 | % 273 | % RELEVANT REQUIREMENTS: none 274 | % 275 | % INPUT DATA: varargin{2}.referenceB, varargin{2}.targetB, 276 | % varargin{3}.gammaB 277 | % 278 | % CONDITION A (+): When computed using identical criteria, CalcGamma 279 | % produces an identical array to the reference with GPU Calculation 280 | % 281 | % CONDITION B (+): When computed using identical criteria, CalcGamma 282 | % produces an identical array to the reference with CPU Calculation 283 | % 284 | % CONDITION C (-): When computed using modified criteria, CalcGamma 285 | % produces a different result 286 | 287 | % Declare gamma criteria 288 | percent = 2; 289 | dta = 0.1; 290 | local = 0; 291 | 292 | % Load reference and target data from varargin 293 | ref = varargin{2}.referenceB; 294 | target = varargin{2}.targetB; 295 | 296 | % Determine location and value of maximum 297 | [C, I] = max(target.data); 298 | 299 | % Search left side for half-maximum value 300 | for x = 1:I-1 301 | if target.data(x) == C/2 302 | left = target.start + target.width * (x-1); 303 | break; 304 | elseif target.data(x) < C/2 && target.data(x+1) > C/2 305 | left = interp1(target.data(x:x+1), target.start + ... 306 | target.width * (x-1:x), C/2); 307 | break; 308 | end 309 | end 310 | 311 | % Search right side for half-maximum value 312 | for x = I:size(target.data,1)-1 313 | if target.data(x) == C/2 314 | right = target.start + target.width * (x-1); 315 | break; 316 | elseif target.data(x) > C/2 && target.data(x+1) < C/2 317 | right = interp1(target.data(x:x+1), target.start + ... 318 | target.width * (x-1:x), C/2); 319 | break; 320 | end 321 | end 322 | 323 | % Center target profile on FWHM 324 | target.start = target.start - (right + left)/2; 325 | 326 | % Execute in try/catch statement 327 | try 328 | 329 | % Execute CalcGamma using test dataset 330 | t = tic; 331 | gamma = CalcGamma(ref, target, percent, dta, 'local', local); 332 | gtime = sprintf('%0.1f sec', toc(t)); 333 | gpf = pass; 334 | cpf = pass; 335 | 336 | % If reference data exists 337 | if nargin == 3 338 | 339 | % If current value does not equal the reference 340 | if max(abs(gamma - varargin{3}.gammaB)) > 1e-5 341 | gpf = fail; 342 | end 343 | 344 | % Execute CalcGamma again using CPU 345 | t = tic; 346 | gamma = CalcGamma(ref, target, percent, dta, 'cpu', 1, ... 347 | 'local', local); 348 | ctime = sprintf('%0.1f sec', toc(t)); 349 | 350 | % If CPU value does not equal the reference 351 | if max(abs(gamma - varargin{3}.gammaB)) > 1e-5 352 | cpf = fail; 353 | end 354 | 355 | % Execute CalcGamma again, this time using modified criteria 356 | gamma = CalcGamma(ref, target, percent, dta, ... 357 | 'local', local, 'limit', 0.1); 358 | 359 | % If modified value equals the reference, the test fails 360 | if max(abs(gamma - varargin{3}.gammaB)) < 1e-5 361 | gpf = fail; 362 | end 363 | 364 | % Execute CalcGamma again, this time using modified criteria 365 | gamma = CalcGamma(ref, target, percent, dta, ... 366 | 'local', local, 'refval', 10); 367 | 368 | % If modified value equals the reference, the test fails 369 | if max(abs(gamma - varargin{3}.gammaB)) < 1e-5 370 | gpf = fail; 371 | end 372 | 373 | % Otherwise, set reference 374 | elseif nargout == 4 375 | reference.gammaB = gamma; 376 | gpf = pass; 377 | cpf = pass; 378 | end 379 | 380 | catch 381 | gpf = fail; 382 | cpf = fail; 383 | end 384 | 385 | % Add the dataset size to the preamble 386 | preamble{length(preamble)+1} = ... 387 | sprintf('| Beam Profile 1D Gamma Array | %i x %i |', size(gamma)); 388 | 389 | % Add GPU computation result 390 | results{size(results,1)+1,1} = '5'; 391 | results{size(results,1),2} = 'Beam Profile 1D Gamma GPU Result within 1e-5'; 392 | results{size(results,1),3} = gpf; 393 | 394 | % Add computation time 395 | results{size(results,1)+1,1} = '6'; 396 | results{size(results,1),2} = 'Beam Profile 1D Gamma GPU Computation Time'; 397 | results{size(results,1),3} = gtime; 398 | 399 | % Add CPU computation result 400 | results{size(results,1)+1,1} = '7'; 401 | results{size(results,1),2} = 'Beam Profile 1D Gamma CPU Result within 1e-5'; 402 | results{size(results,1),3} = cpf; 403 | 404 | % Add computation time 405 | results{size(results,1)+1,1} = '8'; 406 | results{size(results,1),2} = 'Beam Profile 1D Gamma CPU Computation Time'; 407 | results{size(results,1),3} = ctime; 408 | 409 | %% TEST 9/10/11/12: Simple 2D Gamma 410 | % 411 | % DESCRIPTION: This unit test creates a simple analytic reference dataset, 412 | % modifies it by a known amount, and executes CalcGamma. The gamma 413 | % result is then compared to a known solution 414 | % 415 | % RELEVANT REQUIREMENTS: none 416 | % 417 | % INPUT DATA: varargin{3}.gammaC 418 | % 419 | % CONDITION A (+): When computed using identical criteria, CalcGamma 420 | % produces an identical array to the reference with GPU Calculation 421 | % 422 | % CONDITION B (+): When computed using identical criteria, CalcGamma 423 | % produces an identical array to the reference with CPU Calculation 424 | % 425 | % CONDITION C (-): When computed using modified criteria, CalcGamma 426 | % produces a different result 427 | 428 | % Declare Gamma criteria 429 | percent = 3; 430 | dta = 0.3; 431 | local = 0; 432 | res = 20; 433 | 434 | % Declare size of data arrays 435 | n = 100; 436 | 437 | % Create reference data structure (peaks function) 438 | ref.start = [0 0]; 439 | ref.width = [0.01 0.01]; 440 | ref.data = peaks(n) + 5; 441 | 442 | % Declare modification values (to be applied to reference data) 443 | shift = [0.05 0.05]; 444 | scale = 1.03; 445 | 446 | % Modify reference data, saving to target structure 447 | target.start = ref.start + shift; 448 | target.width = ref.width; 449 | target.data = ref.data * scale; 450 | 451 | % Execute in try/catch statement 452 | try 453 | 454 | % Execute CalcGamma using test dataset 455 | t = tic; 456 | gamma = CalcGamma(ref, target, percent, dta, 'local', local, ... 457 | 'res', res); 458 | gtime = sprintf('%0.1f sec', toc(t)); 459 | gpf = pass; 460 | cpf = pass; 461 | 462 | % If reference data exists 463 | if nargin == 3 464 | 465 | % If current value does not equal the reference 466 | if max(max(abs(gamma - varargin{3}.gammaC))) > 1e-5 467 | gpf = fail; 468 | end 469 | 470 | % Execute CalcGamma again using CPU 471 | t = tic; 472 | gamma = CalcGamma(ref, target, percent, dta, 'cpu', 1, ... 473 | 'local', local, 'res', res); 474 | ctime = sprintf('%0.1f sec', toc(t)); 475 | 476 | % If CPU value does not equal the reference 477 | if max(max(abs(gamma - varargin{3}.gammaC))) > 1e-5 478 | cpf = fail; 479 | end 480 | 481 | % Execute CalcGamma again, this time using modified criteria 482 | gamma = CalcGamma(ref, target, percent, dta * 2, ... 483 | 'local', local, 'res', res); 484 | 485 | % If modified value equals the reference, the test fails 486 | if max(max(abs(gamma - varargin{3}.gammaC))) < 1e-5 487 | gpf = fail; 488 | end 489 | 490 | % Execute CalcGamma again, this time using modified criteria 491 | gamma = CalcGamma(ref, target, percent * 2, dta, ... 492 | 'local', local, 'res', res); 493 | 494 | % If modified value equals the reference, the test fails 495 | if max(max(abs(gamma - varargin{3}.gammaC))) < 1e-5 496 | gpf = fail; 497 | end 498 | 499 | % Otherwise, set reference 500 | elseif nargout == 4 501 | reference.gammaC = gamma; 502 | gpf = pass; 503 | cpf = pass; 504 | end 505 | 506 | catch 507 | gpf = fail; 508 | cpf = fail; 509 | end 510 | 511 | % Add the dataset size to the preamble 512 | preamble{length(preamble)+1} = ... 513 | sprintf('| Simple 2D Gamma Array | %i x %i |', size(gamma)); 514 | 515 | % Add GPU computation result 516 | results{size(results,1)+1,1} = '9'; 517 | results{size(results,1),2} = 'Simple 2D Gamma GPU Result within 1e-5'; 518 | results{size(results,1),3} = gpf; 519 | 520 | % Add computation time 521 | results{size(results,1)+1,1} = '10'; 522 | results{size(results,1),2} = 'Simple 2D Gamma GPU Computation Time'; 523 | results{size(results,1),3} = gtime; 524 | 525 | % Add CPU computation result 526 | results{size(results,1)+1,1} = '11'; 527 | results{size(results,1),2} = 'Simple 2D Gamma CPU Result within 1e-5'; 528 | results{size(results,1),3} = cpf; 529 | 530 | % Add computation time 531 | results{size(results,1)+1,1} = '12'; 532 | results{size(results,1),2} = 'Simple 2D Gamma CPU Computation Time'; 533 | results{size(results,1),3} = ctime; 534 | 535 | %% TEST 13/14/15/16: Dose Volume 3D Gamma 536 | % 537 | % DESCRIPTION: This unit test creates a real world dose volume dataset 538 | % and executes CalcGamma. The gamma result is then compared to a known 539 | % solution 540 | % 541 | % RELEVANT REQUIREMENTS: none 542 | % 543 | % INPUT DATA: varargin{2}.referenceD, varargin{2}.targetD, 544 | % varargin{3}.gammaD 545 | % 546 | % CONDITION A (+): When computed using identical criteria, CalcGamma 547 | % produces an identical array to the reference with GPU Calculation 548 | % 549 | % CONDITION B (+): When computed using identical criteria, CalcGamma 550 | % produces an identical array to the reference with CPU Calculation 551 | 552 | % Declare gamma criteria 553 | percent = 3; 554 | dta = 3; 555 | local = 0; 556 | restrict = 1; 557 | 558 | % Load reference and target data from varargin 559 | ref = varargin{2}.referenceD; 560 | target = varargin{2}.targetD; 561 | 562 | % Execute in try/catch statement 563 | try 564 | 565 | % Execute CalcGamma using test dataset 566 | t = tic; 567 | gamma = CalcGamma(ref, target, percent, dta, 'local', local, ... 568 | 'restrict', restrict); 569 | gtime = sprintf('%0.1f sec', toc(t)); 570 | gpf = pass; 571 | cpf = pass; 572 | 573 | % If reference data exists 574 | if nargin == 3 575 | 576 | % If current value does not equal the reference 577 | if max(max(max(abs(gamma - varargin{3}.gammaD)))) > 1e-5 578 | gpf = fail; 579 | end 580 | 581 | % Execute CalcGamma again using CPU 582 | t = tic; 583 | gamma = CalcGamma(ref, target, percent, dta, 'cpu', 1, ... 584 | 'local', local, 'restrict', restrict); 585 | ctime = sprintf('%0.1f sec', toc(t)); 586 | 587 | % If CPU value does not equal the reference 588 | if max(max(max(abs(gamma - varargin{3}.gammaD)))) > 1e-5 589 | cpf = fail; 590 | end 591 | 592 | % Otherwise, set reference 593 | elseif nargout == 4 594 | reference.gammaD = gamma; 595 | gpf = pass; 596 | cpf = pass; 597 | end 598 | 599 | catch 600 | gpf = fail; 601 | cpf = fail; 602 | end 603 | 604 | % Add the dataset size to the preamble 605 | preamble{length(preamble)+1} = ... 606 | sprintf('| Dose Volume 3D Gamma Array | %i x %i x %i |', size(gamma)); 607 | 608 | % Add GPU computation result 609 | results{size(results,1)+1,1} = '13'; 610 | results{size(results,1),2} = 'Dose Volume 3D Gamma GPU Result within 1e-5'; 611 | results{size(results,1),3} = gpf; 612 | 613 | % Add computation time 614 | results{size(results,1)+1,1} = '14'; 615 | results{size(results,1),2} = 'Dose Volume 3D Gamma GPU Computation Time'; 616 | results{size(results,1),3} = gtime; 617 | 618 | % Add CPU computation result 619 | results{size(results,1)+1,1} = '15'; 620 | results{size(results,1),2} = 'Dose Volume 3D Gamma CPU Result within 1e-5'; 621 | results{size(results,1),3} = cpf; 622 | 623 | % Add computation time 624 | results{size(results,1)+1,1} = '16'; 625 | results{size(results,1),2} = 'Dose Volume 3D Gamma CPU Computation Time'; 626 | results{size(results,1),3} = ctime; 627 | 628 | %% TEST 17: Data Validity 629 | % 630 | % DESCRIPTION: This test verifies that CalcGamma correctly fails when input 631 | % data is not valid. This function tests error messages both with an 632 | % without the Event() function. 633 | % 634 | % RELEVANT REQUIREMENTS: none 635 | % 636 | % INPUT DATA: No input data required 637 | % 638 | % CONDITION A (-): CalcGamma fails with too few arguments 639 | % 640 | % CONDITION B (-): CalcGamma fails if the reference structure is poorly 641 | % formatted 642 | % 643 | % CONDITION C (-): CalcGamma fails if the target structure is poorly 644 | % formatted 645 | % 646 | % CONDITION D (-): CalcGamma fails if the reference and target dimensions 647 | % differ 648 | % 649 | % CONDITION E (-): CalcGamma fails if the reference structure contains more 650 | % than three dimensions 651 | % 652 | % CONDITION F (-): CalcGamma fails if the target structure contains more 653 | % than three dimensions 654 | 655 | % Start with passing result 656 | pf = pass; 657 | 658 | % Try to execute CalcGamma with too few arguments 659 | try 660 | CalcGamma(); 661 | pf = fail; 662 | catch 663 | % The test passes if an error is thrown 664 | end 665 | 666 | % Initialize bad data 667 | ref.data = rand(5); 668 | ref.start = [0 0]; 669 | ref.width = [1 1 1]; 670 | target.data = rand(5); 671 | target.start = [0 0]; 672 | target.width = [1 1 1]; 673 | 674 | % Try to execute CalcGamma with bad reference structure 675 | try 676 | CalcGamma(ref, target, 1, 1); 677 | pf = fail; 678 | catch 679 | % The test passes if an error is thrown 680 | end 681 | 682 | % Fix reference 683 | ref.width = [1 1]; 684 | 685 | % Try to execute CalcGamma with bad target structure 686 | try 687 | CalcGamma(ref, target, 1, 1); 688 | pf = fail; 689 | catch 690 | % The test passes if an error is thrown 691 | end 692 | 693 | % Fix target 694 | target.data = rand(5, 5, 5); 695 | target.start = [0 0 0]; 696 | target.width = [1 1 1]; 697 | 698 | % Try to execute CalcGamma with different dimensions 699 | try 700 | CalcGamma(ref, target, 1, 1); 701 | pf = fail; 702 | catch 703 | % The test passes if an error is thrown 704 | end 705 | 706 | % Create 4-D datasets 707 | ref.data = rand(5, 5, 5, 5); 708 | ref.start = [0 0 0 0]; 709 | ref.width = [1 1 1 1]; 710 | target.data = rand(5, 5, 5, 5); 711 | target.start = [0 0 0 0]; 712 | target.width = [1 1 1 1]; 713 | 714 | % Try to execute CalcGamma with different dimensions 715 | try 716 | CalcGamma(ref, target, 1, 1); 717 | pf = fail; 718 | catch 719 | % The test passes if an error is thrown 720 | end 721 | 722 | % Repeat without Event() 723 | restoredefaultpath 724 | 725 | % Try to execute CalcGamma with too few arguments 726 | try 727 | CalcGamma(); 728 | pf = fail; 729 | catch 730 | % The test passes if an error is thrown 731 | end 732 | 733 | % Initialize bad data 734 | ref.data = rand(5); 735 | ref.start = [0 0]; 736 | ref.width = [1 1 1]; 737 | target.data = rand(5); 738 | target.start = [0 0]; 739 | target.width = [1 1 1]; 740 | 741 | % Try to execute CalcGamma with bad reference structure 742 | try 743 | CalcGamma(ref, target, 1, 1); 744 | pf = fail; 745 | catch 746 | % The test passes if an error is thrown 747 | end 748 | 749 | % Fix reference 750 | ref.width = [1 1]; 751 | 752 | % Try to execute CalcGamma with bad target structure 753 | try 754 | CalcGamma(ref, target, 1, 1); 755 | pf = fail; 756 | catch 757 | % The test passes if an error is thrown 758 | end 759 | 760 | % Fix target 761 | target.data = rand(5, 5, 5); 762 | target.start = [0 0 0]; 763 | target.width = [1 1 1]; 764 | 765 | % Try to execute CalcGamma with different dimensions 766 | try 767 | CalcGamma(ref, target, 1, 1); 768 | pf = fail; 769 | catch 770 | % The test passes if an error is thrown 771 | end 772 | 773 | % Create 4-D datasets 774 | ref.data = rand(5, 5, 5, 5); 775 | ref.start = [0 0 0 0]; 776 | ref.width = [1 1 1 1]; 777 | target.data = rand(5, 5, 5, 5); 778 | target.start = [0 0 0 0]; 779 | target.width = [1 1 1 1]; 780 | 781 | % Try to execute CalcGamma with different dimensions 782 | try 783 | CalcGamma(ref, target, 1, 1); 784 | pf = fail; 785 | catch 786 | % The test passes if an error is thrown 787 | end 788 | 789 | % Add test result 790 | results{size(results,1)+1,1} = '17'; 791 | results{size(results,1),2} = 'Data Validation Checks Functional'; 792 | results{size(results,1),3} = pf; 793 | 794 | %% TEST 18/19: Code Analyzer Messages, Cyclomatic Complexity 795 | % 796 | % DESCRIPTION: This unit test uses the checkcode() MATLAB function to check 797 | % each function used by the application and return any Code Analyzer 798 | % messages that result. The cumulative cyclomatic complexity is also 799 | % computed for each function and summed to determine the total 800 | % application complexity. Although this test does not reference any 801 | % particular requirements, it is used during development to help identify 802 | % high risk code. 803 | % 804 | % RELEVANT REQUIREMENTS: none 805 | % 806 | % INPUT DATA: No input data required 807 | % 808 | % CONDITION A (+): Report any code analyzer messages for all functions 809 | % called by CalcGamma 810 | % 811 | % CONDITION B (+): Report the cumulative cyclomatic complexity for all 812 | % functions called by CalcGamma 813 | 814 | % Search for required functions 815 | fList = matlab.codetools.requiredFilesAndProducts('CalcGamma.m'); 816 | 817 | % Initialize complexity and messages counters 818 | comp = 0; 819 | mess = 0; 820 | 821 | % Loop through each dependency 822 | for i = 1:length(fList) 823 | 824 | % Execute checkcode 825 | inform = checkcode(fList{i}, '-cyc'); 826 | 827 | % Loop through results 828 | for j = 1:length(inform) 829 | 830 | % Check for McCabe complexity output 831 | c = regexp(inform(j).message, ... 832 | '^The McCabe complexity .+ is ([0-9]+)\.$', 'tokens'); 833 | 834 | % If regular expression was found 835 | if ~isempty(c) 836 | 837 | % Add complexity 838 | comp = comp + str2double(c{1}); 839 | 840 | else 841 | 842 | % If not an invalid code message 843 | if ~strncmp(inform(j).message, 'Filename', 8) 844 | 845 | % Log message 846 | Event(sprintf('%s in %s', inform(j).message, fList{i}), ... 847 | 'CHCK'); 848 | 849 | % Add as code analyzer message 850 | mess = mess + 1; 851 | end 852 | end 853 | 854 | end 855 | end 856 | 857 | % Add code analyzer messages counter to results 858 | results{size(results,1)+1,1} = '18'; 859 | results{size(results,1),2} = 'Code Analyzer Messages'; 860 | results{size(results,1),3} = sprintf('%i', mess); 861 | 862 | % Add complexity results 863 | results{size(results,1)+1,1} = '19'; 864 | results{size(results,1),2} = 'Cumulative Cyclomatic Complexity'; 865 | results{size(results,1),3} = sprintf('%i', comp); 866 | 867 | %% Finish up 868 | % Close all figures 869 | close all force; 870 | 871 | % If no return variables are present, print the results 872 | if nargout == 0 873 | 874 | % Print preamble 875 | for j = 1:length(preamble) 876 | fprintf('%s\n', preamble{j}); 877 | end 878 | fprintf('\n'); 879 | 880 | % Loop through each table row 881 | for j = 1:size(results,1) 882 | 883 | % Print table row 884 | fprintf('| %s |\n', strjoin(results(j,:), ' | ')); 885 | 886 | % If this is the first column 887 | if j == 1 888 | 889 | % Also print a separator row 890 | fprintf('|%s\n', repmat('----|', 1, size(results,2))); 891 | end 892 | 893 | end 894 | fprintf('\n'); 895 | 896 | % Print footnotes 897 | for j = 1:length(footnotes) 898 | fprintf('%s
\n', footnotes{j}); 899 | end 900 | 901 | % Otherwise, return the results as variables 902 | else 903 | 904 | % Store return variables 905 | if nargout >= 1; varargout{1} = preamble; end 906 | if nargout >= 2; varargout{2} = results; end 907 | if nargout >= 3; varargout{3} = footnotes; end 908 | if nargout >= 4; varargout{4} = reference; end 909 | end 910 | -------------------------------------------------------------------------------- /CalcGamma.m: -------------------------------------------------------------------------------- 1 | function gamma = CalcGamma(varargin) 2 | % CalcGamma computes 1-D, 2-D, or 3-D global or absolute gamma between two 3 | % datasets (reference and target) given a defined coordinate space. The 4 | % datasets must have the same number of dimensions, although they can be 5 | % different sizes. Gamma will be computed for each target dose point by 6 | % shifting the reference image (using linear interpolation) and determining 7 | % the minimum Gamma index across all shifts. 8 | % 9 | % This function optionally uses the Parallel Computing Toolbox GPU interp 10 | % functions to increase computation speed. A try-catch statement is used 11 | % to test for GPU support. In addition, for memory management, the 12 | % meshgrid and data arrays are converted to single precision during 13 | % interpolation. This function calls Event() to log execution status, if 14 | % available. 15 | % 16 | % For more information on the Gamma evaluation function, see D. A. Low et 17 | % al., "A technique for the quantitative evaluation of dose distributions", 18 | % Med Phys. 1998 May; 25(5): 656-61. 19 | % 20 | % The following variables are required for proper execution: 21 | % varargin{1}: structure containing the reference data, where the field 22 | % start is an array containing the coordinates along each dimension 23 | % of the first voxel, width is an array containing the width of each 24 | % voxel along each dimension, and data is an n-dimensional array 25 | % varargin{2}: structure containing the target data, where the field 26 | % start is an array containing the coordinates along each dimension 27 | % of the first voxel, width is an array containing the width of each 28 | % voxel along each dimension, and data is an n-dimensional array 29 | % varargin{3}: Gamma absolute criterion percentage 30 | % varargin{4}: Gamma Distance To Agreement (DTA) criterion, in the same 31 | % units as the reference and target width structure fields 32 | % varargin{5:end} (optional): additional parameters preceded by option 33 | % flags. The available options are 'local', 'refval', 'restrict', 34 | % 'res', and 'limit'. 35 | % 36 | % The following options can be passed to this argument as name/value pairs: 37 | % local: boolean, indicates whether to perform a local (1) or global (0) 38 | % Gamma computation. If not present, the function will assume a 39 | % global Gamma computation. 40 | % refval: reference value for the global absolute criterion. Is used with 41 | % the percentage from varargin{3} to compute absolute value. If not 42 | % present, the maximum value in the reference data is used. 43 | % restrict: restricted search flag. If 1 or not provided, only the gamma 44 | % values along the X/Y/Z axes are computed during 3D comptation. If 45 | % 0, the entire rectangular/volumetric search space is computed. 46 | % res: DTA resolution factor. The number of distance steps equal the 47 | % resolution factor multiplied by the limit. If not provided, the 48 | % factor is 100 for 1D/2D and 20 for 3D calculations. 49 | % limit: The DTA limit. This number determines how far the function will 50 | % search in the distance axes when computing Gamma. This also 51 | % therefore specifies the maximum "real" Gamma Index value. 52 | % cpu: boolean, set to 1 to force CPU computation. 53 | % 54 | % The following variables are returned upon succesful completion: 55 | % gamma: array of the same dimensions as varargin{2}.data containing the 56 | % computed gamma values 57 | % 58 | % Below is an example of how the function is used: 59 | % 60 | % reference.start = [-10 -10]; % mm 61 | % reference.width = [0.1 0.1]; % mm 62 | % reference.data = rand(200); 63 | % 64 | % target.start = [-10 -10]; % mm 65 | % target.width = [0.1 0.1]; % mm 66 | % target.data = rand(200); 67 | % 68 | % percent = 3; 69 | % dta = 0.5; % mm 70 | % local = 0; % Perform global gamma 71 | % 72 | % gamma = CalcGamma(reference, target, percent, dta, 'local', local); 73 | % 74 | % Author: Mark Geurts, mark.w.geurts@gmail.com 75 | % Copyright (C) 2014 University of Wisconsin Board of Regents 76 | % 77 | % This program is free software: you can redistribute it and/or modify it 78 | % under the terms of the GNU General Public License as published by the 79 | % Free Software Foundation, either version 3 of the License, or (at your 80 | % option) any later version. 81 | % 82 | % This program is distributed in the hope that it will be useful, but 83 | % WITHOUT ANY WARRANTY; without even the implied warranty of 84 | % MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General 85 | % Public License for more details. 86 | % 87 | % You should have received a copy of the GNU General Public License along 88 | % with this program. If not, see http://www.gnu.org/licenses/. 89 | 90 | %% Validate Inputs 91 | % Verify at least four input arguments are provided 92 | if nargin < 4 93 | 94 | % If not, throw an error and stop execution 95 | if exist('Event', 'file') == 2 96 | Event('Too few input argumenst passed to CalcGamma', 'ERROR'); 97 | else 98 | error('Too few input argumenst passed to CalcGamma'); 99 | end 100 | end 101 | 102 | % Check if the reference structure contains width, start, and data fields, 103 | % and if the size of the width and start vectors are equal 104 | if ~isfield(varargin{1}, 'width') || ~isfield(varargin{1}, 'start') || ... 105 | ~isfield(varargin{1}, 'data') || ~isequal(length(varargin{1}.width), ... 106 | length(varargin{1}.start)) 107 | 108 | % If not, throw an error and stop execution 109 | if exist('Event', 'file') == 2 110 | Event(['Incorrect reference data format. Must contain width, ', ... 111 | 'start, and data fields and be of equal dimensions'], 'ERROR'); 112 | else 113 | error(['Incorrect reference data format. Must contain width, ', ... 114 | 'start, and data fields and be of equal dimensions']); 115 | end 116 | 117 | % Check if the target structure contains width, start, and data fields, 118 | % and if the size of the width and start vectors are equal 119 | elseif ~isfield(varargin{2}, 'width') || ~isfield(varargin{2}, 'start') || ... 120 | ~isfield(varargin{2}, 'data') || ~isequal(length(varargin{2}.width), ... 121 | length(varargin{2}.start)) 122 | 123 | % If not, throw an error and stop execution 124 | if exist('Event', 'file') == 2 125 | Event(['Incorrect target data format. Must contain width, ', ... 126 | 'start, and data fields and be of equal dimensions'], 'ERROR'); 127 | else 128 | error(['Incorrect target data format. Must contain width, ', ... 129 | 'start, and data fields and be of equal dimensions']); 130 | end 131 | 132 | % Check if the reference and target data arrays are the same number of 133 | % dimensions. Calculating the gamma from a lower dimensional dataset to a 134 | % higher dimensional reference is currently not supported 135 | elseif ~isequal(size(size(varargin{1}.data)), size(size(varargin{2}.data))) 136 | 137 | % If not, throw an error and stop execution 138 | if exist('Event', 'file') == 2 139 | Event(['The fixed and target data arrays must be of the same', ... 140 | ' dimensions'], 'ERROR'); 141 | else 142 | error(['The fixed and target data arrays must be of the same', ... 143 | ' dimensions']); 144 | end 145 | end 146 | 147 | % Log validation completed 148 | if exist('Event', 'file') == 2 149 | Event('Data validation completed, beginning Gamma computation'); 150 | tic; 151 | end 152 | 153 | %% Declare default options 154 | % local indicates whether to perform a local (1) or global (0) Gamma 155 | % computation. If not present, the function will assume a global Gamma 156 | % computation. 157 | local = 0; 158 | 159 | % refval is the reference value for the global absolute criterion. Is used 160 | % with the percentage from varargin{3} to compute absolute value. If not 161 | % present, the maximum value in the reference data is used. 162 | refval = max(max(max(varargin{1}.data))); 163 | 164 | % restricted search flag. If 1, only the gamma values along the X/Y/Z axes 165 | % are computed during 3D comptation. If 0, the entire rectangular/ 166 | % volumetric search space is computed. 167 | restrict = 1; 168 | 169 | % The resolution parameter determines the number of steps (relative to 170 | % the distance to agreement) that each reference voxel will be 171 | % interpolated to and gamma calculated. A value of 5 with a DTA of 3 172 | % mm means that gamma will be calculated at intervals of 3/5 = 0.6 mm. 173 | % Different resolutions can be set for different dimensions of data. 174 | if size(varargin{2}.width,2) == 1 175 | 176 | % Set 1-D resolution 177 | res = 100; 178 | 179 | elseif size(varargin{2}.width,2) == 2 180 | 181 | % Set 2-D resolution 182 | res = 50; 183 | 184 | elseif size(varargin{2}.width,2) == 3 185 | 186 | % Set 3-D resolution 187 | res = 20; 188 | 189 | end 190 | 191 | % The search limit parameter determines how far the function will search in 192 | % the distance axes when computing Gamma. This also therefore specifies 193 | % the maximum believable Gamma Index value. Typically this value is 2. 194 | % This should always be set to an integer. 195 | limit = 2; 196 | 197 | %% Search for provided options 198 | % Load data structure from varargin 199 | for i = 5:nargin 200 | 201 | % If the local option is set 202 | if strcmp(varargin{i}, 'local') 203 | local = varargin{i+1}; 204 | 205 | % If the refval option is set 206 | elseif strcmp(varargin{i}, 'refval') 207 | refval = varargin{i+1}; 208 | 209 | % If the restrict option is set 210 | elseif strcmp(varargin{i}, 'restrict') 211 | restrict = varargin{i+1}; 212 | 213 | % If the res option is set 214 | elseif strcmp(varargin{i}, 'res') 215 | res = varargin{i+1}; 216 | 217 | % If the limit option is set 218 | elseif strcmp(varargin{i}, 'limit') 219 | limit = varargin{i+1}; 220 | 221 | % If the cpu option is set 222 | elseif strcmp(varargin{i}, 'cpu') 223 | cpu = varargin{i+1}; 224 | end 225 | end 226 | 227 | %% Log options 228 | % If Event reporting is enabled 229 | if exist('Event', 'file') == 2 230 | 231 | % Log local 232 | if local == 1 233 | Event('Gamma calculation set to local'); 234 | else 235 | Event('Gamma calculation assumed to global'); 236 | end 237 | 238 | % Log refval 239 | Event(sprintf('Reference value set to %g', refval)); 240 | 241 | % Log restrict 242 | if restrict == 1 243 | Event('Restricted search enabled'); 244 | else 245 | Event('Restricted search disabled'); 246 | end 247 | 248 | % Log res 249 | Event(sprintf('Resolution set to %g', res)); 250 | 251 | % Log limit 252 | Event(sprintf('DTA limit set to %g', limit)); 253 | end 254 | 255 | %% Compute mesh grids 256 | % If the reference dataset is 1-D 257 | if length(varargin{1}.width) == 1 258 | 259 | % Log event 260 | if exist('Event', 'file') == 2 261 | Event('Reference dataset is 1-D'); 262 | end 263 | 264 | % Check if the data is in rows or columns (this is only needed for 1-D) 265 | if size(varargin{1}.data,1) > size(varargin{1}.data,2) 266 | 267 | % If in rows, transpose 268 | varargin{1}.data = varargin{1}.data'; 269 | end 270 | 271 | % Compute the reference X coordinates using the start and width values 272 | refX = single(varargin{1}.start(1):varargin{1}.width(1):varargin{1}.start(1) ... 273 | + varargin{1}.width(1) * (size(varargin{1}.data,2) - 1)); 274 | 275 | % Otherwise, if the reference dataset is 2-D 276 | elseif length(varargin{1}.width) == 2 277 | 278 | % Log event 279 | if exist('Event', 'file') == 2 280 | Event('Reference dataset is 2-D'); 281 | end 282 | 283 | % Compute X and Y meshgrids for the reference dataset positions using 284 | % the start and width values 285 | [refX, refY] = meshgrid(single(varargin{1}.start(2): ... 286 | varargin{1}.width(2):varargin{1}.start(2) + varargin{1}.width(2) * ... 287 | (size(varargin{1}.data,2) - 1)), single(varargin{1}.start(1): ... 288 | varargin{1}.width(1):varargin{1}.start(1) + varargin{1}.width(1)... 289 | * (size(varargin{1}.data,1) - 1))); 290 | 291 | % Otherwise, if the reference dataset is 3-D 292 | elseif length(varargin{1}.width) == 3 293 | 294 | % Log event 295 | if exist('Event', 'file') == 2 296 | Event('Reference dataset is 3-D'); 297 | end 298 | 299 | % Compute X, Y, and Z meshgrids for the reference dataset positions 300 | % using the start and width values, permuting X/Y 301 | [refX, refY, refZ] = meshgrid(single(varargin{1}.start(2): ... 302 | varargin{1}.width(2):varargin{1}.start(2) + varargin{1}.width(2) * ... 303 | (size(varargin{1}.data,2) - 1)), single(varargin{1}.start(1): ... 304 | varargin{1}.width(1):varargin{1}.start(1) + varargin{1}.width(1)... 305 | * (size(varargin{1}.data,1) - 1)), single(varargin{1}.start(3):... 306 | varargin{1}.width(3):varargin{1}.start(3) + varargin{1}.width(3)... 307 | * (size(varargin{1}.data,3) - 1))); 308 | 309 | % Otherwise, if the reference data is of higher dimension 310 | else 311 | 312 | % Throw an error and stop execution 313 | if exist('Event', 'file') == 2 314 | Event('The fixed data structure contains too many dimensions', ... 315 | 'ERROR'); 316 | else 317 | error('The fixed data structure contains too many dimensions'); 318 | end 319 | end 320 | 321 | % If the target dataset is 1-D 322 | if length(varargin{2}.width) == 1 323 | 324 | % Log event 325 | if exist('Event', 'file') == 2 326 | Event('Target dataset is 1-D'); 327 | end 328 | 329 | % Check if the data is in rows or columns (this is only needed for 1-D) 330 | if size(varargin{2}.data,1) > size(varargin{2}.data,2) 331 | 332 | % If in rows, transpose 333 | varargin{2}.data = varargin{2}.data'; 334 | end 335 | 336 | % Compute the target X coordinates using the start and width values 337 | tarX = single(varargin{2}.start(1):varargin{2}.width(1):varargin{2}.start(1) ... 338 | + varargin{2}.width(1) * (size(varargin{2}.data,2) - 1)); 339 | 340 | % Otherwise, if the target dataset is 2-D 341 | elseif length(varargin{2}.width) == 2 342 | 343 | % Log event 344 | if exist('Event', 'file') == 2 345 | Event('Target dataset is 2-D'); 346 | end 347 | 348 | % Compute X and Y meshgrids for the target dataset positions using the 349 | % start and width values 350 | [tarX, tarY] = meshgrid(single(varargin{2}.start(2):... 351 | varargin{2}.width(2):varargin{2}.start(2) + varargin{2}.width(2) * ... 352 | (size(varargin{2}.data,2) - 1)), single(varargin{2}.start(1): ... 353 | varargin{2}.width(1):varargin{2}.start(1) + varargin{2}.width(1) ... 354 | * (size(varargin{2}.data,1) - 1))); 355 | 356 | % Otherwise, if the target dataset is 3-D 357 | elseif length(varargin{2}.width) == 3 358 | 359 | % Log event 360 | if exist('Event', 'file') == 2 361 | Event('Target dataset is 3-D'); 362 | end 363 | 364 | % Compute X, Y, and Z meshgrids for the target dataset positions using 365 | % the start and width values, permuting X/Y 366 | [tarX, tarY, tarZ] = meshgrid(single(varargin{2}.start(2):... 367 | varargin{2}.width(2):varargin{2}.start(2) + varargin{2}.width(2) * ... 368 | (size(varargin{2}.data,2) - 1)), single(varargin{2}.start(1): ... 369 | varargin{2}.width(1):varargin{2}.start(1) + varargin{2}.width(1) ... 370 | * (size(varargin{2}.data,1) - 1)), single(varargin{2}.start(3):... 371 | varargin{2}.width(3):varargin{2}.start(3) + varargin{2}.width(3) ... 372 | * (size(varargin{2}.data,3) - 1))); 373 | 374 | end 375 | 376 | %% Initialize variables 377 | % Generate an initial gamma volume with values of 2^2 (this is the maximum 378 | % reliable value of gamma, see description of limit above). Note that 379 | % gamma-squared is stored during computation; sqrt is computed at the end. 380 | gamma = ones(size(varargin{2}.data)) * (limit ^ 2); 381 | 382 | % Log number of gamma calculations (for status updates on 3D calcs) 383 | if restrict == 1 384 | 385 | % Compute number of restricted search calcs 386 | num = (res * (limit * 2) + 1) * length(varargin{2}.width); 387 | else 388 | 389 | % Compute total number of calcs 390 | num = (res * (limit * 2) + 1) ^ length(varargin{2}.width); 391 | end 392 | 393 | % num is the number of iterations, num * numel the total number of 394 | % interpolations being performed 395 | if exist('Event', 'file') == 2 396 | Event(sprintf('Number of gamma calculations = %g', num * numel(gamma))); 397 | end 398 | 399 | % Initialize counter (for progress indicator) 400 | n = 0; 401 | 402 | %% Begin computation 403 | % Start try-catch block to safely test for CUDA functionality 404 | try 405 | % If the cpu option is set, throw an error to force CPU computation 406 | if exist('cpu', 'var') == 1 && cpu == 1 407 | error('Reverting to CPU computation'); 408 | end 409 | 410 | % Clear and initialize GPU memory. If CUDA is not enabled, or if the 411 | % Parallel Computing Toolbox is not installed, this will error, and the 412 | % function will automatically rever to CPU computation via the catch 413 | % statement 414 | gpuDevice(1); 415 | 416 | % Start a for loop to interpolate the dose array along the x-direction. 417 | % Note to support parfor loops indices must be integers, so x varies 418 | % from -2 to +2 multiplied by the number of interpolation steps. 419 | % Effectively, this evaluates gamma from -2 * DTA to +2 * DTA. 420 | for x = -limit*res:limit*res 421 | 422 | % i is the x axis step value 423 | i = x/res * varargin{4}; 424 | 425 | % Initialize j and k as zero (they will be updated if the data is 426 | % of higher dimension) 427 | j = 0; 428 | k = 0; 429 | 430 | % If the data contains a second dimension 431 | if length(varargin{1}.width) > 1 432 | 433 | % Start a for loop to interpolate the dose array along the 434 | % y-direction. Note to support parfor loops indices must be 435 | % integers, so y varies from -2 to +2 multiplied by the number 436 | % of interpolation steps. Effectively, this evaluates gamma 437 | % from -2 * DTA to +2 * DTA. 438 | for y = -limit*res:limit*res 439 | 440 | % j is the y axis step value 441 | j = y/res * varargin{4}; 442 | 443 | % Initialize k as zero (it will be updated if the data is 444 | % of higher dimension) 445 | k = 0; 446 | 447 | % If the data contains a third dimension 448 | if length(varargin{1}.width) > 2 449 | 450 | % Start a for loop to interpolate the dose array along 451 | % the z-direction. Note to support parfor loops 452 | % indices must be integers, so z varies from -2 to +2 453 | % multiplied by the number of interpolation steps. 454 | % Effectively, this evaluates gamma from -2 * DTA to 455 | % +2 * DTA. 456 | for z = -limit*res:limit*res 457 | 458 | % k is the z axis step value 459 | k = z/res * varargin{4}; 460 | 461 | % Check restricted search flag 462 | if restrict == 0 || sum(abs([x y z]) > 0) == 1 463 | 464 | % Run GPU interp3 function to compute the reference 465 | % values at the specified target coordinate points 466 | interp = gather(interp3(gpuArray(refX), gpuArray(refY), ... 467 | gpuArray(refZ), gpuArray(single(varargin{1}.data)), ... 468 | gpuArray(tarX + i), gpuArray(tarY + j), ... 469 | gpuArray(tarZ + k), 'linear', 0)); 470 | 471 | % Update the gamma array by returning the minimum 472 | % of the existing value or the new value 473 | gamma = min(gamma, GammaEquation(interp, ... 474 | varargin{2}.data, i, j, k, varargin{3}, varargin{4}, ... 475 | refval, local)); 476 | 477 | % Update counter 478 | n = n + 1; 479 | 480 | % If counter is at an even %, display progress 481 | if mod((n-1)/num, 0.01) > 0.005 && ... 482 | mod(n/num, 0.01) < 0.005 483 | fprintf('%0.1f%%\n', n/num*100); 484 | end 485 | end 486 | end 487 | 488 | % Otherwise, the data is 2-D 489 | else 490 | 491 | % Run GPU interp2 function to compute the reference 492 | % values at the specified target coordinate points 493 | interp = gather(interp2(gpuArray(refX), gpuArray(refY), ... 494 | gpuArray(single(varargin{1}.data)), gpuArray(tarX + i), ... 495 | gpuArray(tarY + j), 'linear', 0)); 496 | 497 | % Update the gamma array by returning the minimum 498 | % of the existing value or the new value 499 | gamma = min(gamma, GammaEquation(interp, varargin{2}.data, ... 500 | i, j, k, varargin{3}, varargin{4}, ... 501 | refval, local)); 502 | end 503 | end 504 | 505 | % Otherwise, the data is 1-D 506 | else 507 | 508 | % Run GPU interp function to compute the reference values at 509 | % the specified target coordinate points 510 | interp = gather(interp1(gpuArray(refX), ... 511 | gpuArray(single(varargin{1}.data)), gpuArray(tarX + i), ... 512 | 'linear', 0)); 513 | 514 | % Update the gamma array by returning the minimum of the 515 | % existing value or the new value 516 | gamma = min(gamma, GammaEquation(interp, varargin{2}.data, ... 517 | i, j, k, varargin{3}, varargin{4}, ... 518 | refval, local)); 519 | end 520 | end 521 | 522 | % If GPU fails, revert to CPU computation 523 | catch 524 | 525 | % Log GPU failure (if cpu flag is not set) 526 | if exist('Event', 'file') == 2 && exist('cpu', 'var') ~= 1 527 | Event('GPU failed, reverting to CPU method', 'WARN'); 528 | end 529 | 530 | % Start a for loop to interpolate the dose array along the x-direction. 531 | % Note to support parfor loops indices must be integers, so x varies 532 | % from -2 to +2 multiplied by the number of interpolation steps. 533 | % Effectively, this evaluates gamma from -2 * DTA to +2 * DTA. 534 | for x = -limit*res:limit*res 535 | 536 | % i is the x axis step value 537 | i = x/res * varargin{4}; 538 | 539 | % Initialize j and k as zero (they will be updated if the data is 540 | % of higher dimension) 541 | j = 0; 542 | k = 0; 543 | 544 | % If the data contains a second dimension 545 | if length(varargin{1}.width) > 1 546 | 547 | % Start a for loop to interpolate the dose array along the 548 | % y-direction. Note to support parfor loops indices must be 549 | % integers, so y varies from -2 to +2 multiplied by the number 550 | % of interpolation steps. Effectively, this evaluates gamma 551 | % from -2 * DTA to +2 * DTA. 552 | for y = -limit*res:limit*res 553 | 554 | % j is the y axis step value 555 | j = y/res * varargin{4}; 556 | 557 | % Initialize k as zero (it will be updated if the data is 558 | % of higher dimension) 559 | k = 0; 560 | 561 | % If the data contains a third dimension 562 | if length(varargin{1}.width) > 2 563 | 564 | % Start a for loop to interpolate the dose array along 565 | % the z-direction. Note to support parfor loops 566 | % indices must be integers, so z varies from -2 to +2 567 | % multiplied by the number of interpolation steps. 568 | % Effectively, this evaluates gamma from -2 * DTA to 569 | % +2 * DTA. 570 | for z = -limit*res:limit*res 571 | 572 | % k is the z axis step value 573 | k = z/res * varargin{4}; 574 | 575 | % Check restricted search flag 576 | if restrict == 0 || sum(abs([x y z]) > 0) == 1 577 | 578 | % Run CPU interp3 function to compute the reference 579 | % values at the specified target coordinate points 580 | interp = interp3(refX, refY, refZ, ... 581 | single(varargin{1}.data), tarX + i, ... 582 | tarY + j, tarZ + k, '*linear', 0); 583 | 584 | % Update the gamma array by returning the minimum 585 | % of the existing value or the new value 586 | gamma = min(gamma, GammaEquation(interp, ... 587 | varargin{2}.data, i, j, k, varargin{3}, ... 588 | varargin{4}, refval, local)); 589 | 590 | % Update counter 591 | n = n + 1; 592 | 593 | % If counter is at an even %, display progress 594 | if mod((n-1)/num, 0.01) > 0.005 && ... 595 | mod(n/num, 0.01) < 0.005 596 | fprintf('%0.1f%%\n', n/num*100); 597 | end 598 | end 599 | end 600 | 601 | % Otherwise, the data is 2-D 602 | else 603 | 604 | % Run CPU interp2 function to compute the reference 605 | % values at the specified target coordinate points 606 | interp = interp2(refX, refY, single(varargin{1}.data), ... 607 | tarX + i, tarY + j, '*linear', 0); 608 | 609 | % Update the gamma array by returning the minimum 610 | % of the existing value or the new value 611 | gamma = min(gamma, GammaEquation(interp, ... 612 | varargin{2}.data, i, j, k, varargin{3}, ... 613 | varargin{4}, refval, local)); 614 | end 615 | end 616 | 617 | % Otherwise, the data is 1-D 618 | else 619 | 620 | % Run CPU interp function to compute the reference values at 621 | % the specified target coordinate points 622 | interp = interp1(refX, single(varargin{1}.data), tarX + i, ... 623 | '*linear', 0); 624 | 625 | % Update the gamma array by returning the minimum of the 626 | % existing value or the new value 627 | gamma = min(gamma, GammaEquation(interp, varargin{2}.data, ... 628 | i, j, k, varargin{3}, varargin{4}, ... 629 | refval, local)); 630 | end 631 | end 632 | end 633 | 634 | %% Finish up 635 | % Take square root of result 636 | gamma = sqrt(gamma); 637 | 638 | % Log completion 639 | if exist('Event', 'file') == 2 640 | Event(sprintf(['Gamma calculation completed successfully in ', ... 641 | '%0.3f seconds'], toc)); 642 | end 643 | 644 | % Clear temporary variables 645 | clear refX refY refZ tarX tarY tarZ interp; 646 | 647 | %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% 648 | function gamma = GammaEquation(ref, tar, i, j, k, perc, dta, refval, local) 649 | % GammaEquation is the programmatic form of the Gamma definition as given 650 | % by Low et al in matrix form. This function computes both local and 651 | % global Gamma, and is a subfunction for CalcGamma. Note that this 652 | % equation returns Gamma-squared instead of Gamma. 653 | % 654 | % The following inputs are used for computation and are required: 655 | % ref: the reference 3D array. Must be the same size as tar 656 | % tar: the target 3D array. Must be the same size as ref 657 | % i: magnitude of x position offset of tar to ref, relative to dta 658 | % j: magnitude of y position offset of tar to ref, relative to dta 659 | % k: magnitude of z position offset of tar to ref, relative to dta 660 | % perc: the percent Gamma criterion, given in % (i.e. 3 for 3%) 661 | % dta: the distance to agreement Gamma criterion, unitless but relative 662 | % to i, j, and k 663 | % refval: if global, the reference value to base the % criterion from 664 | % local: boolean, indicates whether to perform a local (1) or global (0) 665 | % Gamma computation 666 | % 667 | % The following variables are returned: 668 | % gamma: a 3D array of the same dimensions as ref and interp of the 669 | % computed gamma-squared value for each voxel based on interp and 670 | % i, j, k 671 | 672 | % If local is set to 1, perform a local Gamma computation 673 | if local == 1 674 | 675 | % Gamma is defined as the sqrt((abs difference/relative tolerance)^2 + 676 | % sum((voxel offset/dta)^2)). The sqrt is removed for computational 677 | % efficiency. 678 | gamma = ((tar - ref) ./ (ref * perc / 100)).^2 + ... 679 | (i/dta)^2 + (j/dta)^2 + (k/dta)^2; 680 | else 681 | 682 | % Gamma is defined as the sqrt((abs difference/absolute tolerance)^2 + 683 | % sum((voxel offset/dta)^2)). The sqrt is removed for computational 684 | % efficiency. 685 | gamma = ((tar - ref) ./ (refval * perc / 100)).^2 + ... 686 | (i/dta)^2 + (j/dta)^2 + (k/dta)^2; 687 | end 688 | -------------------------------------------------------------------------------- /LICENSE: -------------------------------------------------------------------------------- 1 | GNU GENERAL PUBLIC LICENSE 2 | Version 3, 29 June 2007 3 | 4 | Copyright (C) 2007 Free Software Foundation, Inc. 5 | Everyone is permitted to copy and distribute verbatim copies 6 | of this license document, but changing it is not allowed. 7 | 8 | Preamble 9 | 10 | The GNU General Public License is a free, copyleft license for 11 | software and other kinds of works. 12 | 13 | The licenses for most software and other practical works are designed 14 | to take away your freedom to share and change the works. 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No Surrender of Others' Freedom. 541 | 542 | If conditions are imposed on you (whether by court order, agreement or 543 | otherwise) that contradict the conditions of this License, they do not 544 | excuse you from the conditions of this License. If you cannot convey a 545 | covered work so as to satisfy simultaneously your obligations under this 546 | License and any other pertinent obligations, then as a consequence you may 547 | not convey it at all. For example, if you agree to terms that obligate you 548 | to collect a royalty for further conveying from those to whom you convey 549 | the Program, the only way you could satisfy both those terms and this 550 | License would be to refrain entirely from conveying the Program. 551 | 552 | 13. Use with the GNU Affero General Public License. 553 | 554 | Notwithstanding any other provision of this License, you have 555 | permission to link or combine any covered work with a work licensed 556 | under version 3 of the GNU Affero General Public License into a single 557 | combined work, and to convey the resulting work. The terms of this 558 | License will continue to apply to the part which is the covered work, 559 | but the special requirements of the GNU Affero General Public License, 560 | section 13, concerning interaction through a network will apply to the 561 | combination as such. 562 | 563 | 14. Revised Versions of this License. 564 | 565 | The Free Software Foundation may publish revised and/or new versions of 566 | the GNU General Public License from time to time. Such new versions will 567 | be similar in spirit to the present version, but may differ in detail to 568 | address new problems or concerns. 569 | 570 | Each version is given a distinguishing version number. If the 571 | Program specifies that a certain numbered version of the GNU General 572 | Public License "or any later version" applies to it, you have the 573 | option of following the terms and conditions either of that numbered 574 | version or of any later version published by the Free Software 575 | Foundation. If the Program does not specify a version number of the 576 | GNU General Public License, you may choose any version ever published 577 | by the Free Software Foundation. 578 | 579 | If the Program specifies that a proxy can decide which future 580 | versions of the GNU General Public License can be used, that proxy's 581 | public statement of acceptance of a version permanently authorizes you 582 | to choose that version for the Program. 583 | 584 | Later license versions may give you additional or different 585 | permissions. However, no additional obligations are imposed on any 586 | author or copyright holder as a result of your choosing to follow a 587 | later version. 588 | 589 | 15. Disclaimer of Warranty. 590 | 591 | THERE IS NO WARRANTY FOR THE PROGRAM, TO THE EXTENT PERMITTED BY 592 | APPLICABLE LAW. EXCEPT WHEN OTHERWISE STATED IN WRITING THE COPYRIGHT 593 | HOLDERS AND/OR OTHER PARTIES PROVIDE THE PROGRAM "AS IS" WITHOUT WARRANTY 594 | OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING, BUT NOT LIMITED TO, 595 | THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR 596 | PURPOSE. THE ENTIRE RISK AS TO THE QUALITY AND PERFORMANCE OF THE PROGRAM 597 | IS WITH YOU. SHOULD THE PROGRAM PROVE DEFECTIVE, YOU ASSUME THE COST OF 598 | ALL NECESSARY SERVICING, REPAIR OR CORRECTION. 599 | 600 | 16. Limitation of Liability. 601 | 602 | IN NO EVENT UNLESS REQUIRED BY APPLICABLE LAW OR AGREED TO IN WRITING 603 | WILL ANY COPYRIGHT HOLDER, OR ANY OTHER PARTY WHO MODIFIES AND/OR CONVEYS 604 | THE PROGRAM AS PERMITTED ABOVE, BE LIABLE TO YOU FOR DAMAGES, INCLUDING ANY 605 | GENERAL, SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES ARISING OUT OF THE 606 | USE OR INABILITY TO USE THE PROGRAM (INCLUDING BUT NOT LIMITED TO LOSS OF 607 | DATA OR DATA BEING RENDERED INACCURATE OR LOSSES SUSTAINED BY YOU OR THIRD 608 | PARTIES OR A FAILURE OF THE PROGRAM TO OPERATE WITH ANY OTHER PROGRAMS), 609 | EVEN IF SUCH HOLDER OR OTHER PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF 610 | SUCH DAMAGES. 611 | 612 | 17. Interpretation of Sections 15 and 16. 613 | 614 | If the disclaimer of warranty and limitation of liability provided 615 | above cannot be given local legal effect according to their terms, 616 | reviewing courts shall apply local law that most closely approximates 617 | an absolute waiver of all civil liability in connection with the 618 | Program, unless a warranty or assumption of liability accompanies a 619 | copy of the Program in return for a fee. 620 | 621 | END OF TERMS AND CONDITIONS 622 | 623 | How to Apply These Terms to Your New Programs 624 | 625 | If you develop a new program, and you want it to be of the greatest 626 | possible use to the public, the best way to achieve this is to make it 627 | free software which everyone can redistribute and change under these terms. 628 | 629 | To do so, attach the following notices to the program. It is safest 630 | to attach them to the start of each source file to most effectively 631 | state the exclusion of warranty; and each file should have at least 632 | the "copyright" line and a pointer to where the full notice is found. 633 | 634 | {one line to give the program's name and a brief idea of what it does.} 635 | Copyright (C) {year} {name of author} 636 | 637 | This program is free software: you can redistribute it and/or modify 638 | it under the terms of the GNU General Public License as published by 639 | the Free Software Foundation, either version 3 of the License, or 640 | (at your option) any later version. 641 | 642 | This program is distributed in the hope that it will be useful, 643 | but WITHOUT ANY WARRANTY; without even the implied warranty of 644 | MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the 645 | GNU General Public License for more details. 646 | 647 | You should have received a copy of the GNU General Public License 648 | along with this program. If not, see . 649 | 650 | Also add information on how to contact you by electronic and paper mail. 651 | 652 | If the program does terminal interaction, make it output a short 653 | notice like this when it starts in an interactive mode: 654 | 655 | {project} Copyright (C) {year} {fullname} 656 | This program comes with ABSOLUTELY NO WARRANTY; for details type `show w'. 657 | This is free software, and you are welcome to redistribute it 658 | under certain conditions; type `show c' for details. 659 | 660 | The hypothetical commands `show w' and `show c' should show the appropriate 661 | parts of the General Public License. Of course, your program's commands 662 | might be different; for a GUI interface, you would use an "about box". 663 | 664 | You should also get your employer (if you work as a programmer) or school, 665 | if any, to sign a "copyright disclaimer" for the program, if necessary. 666 | For more information on this, and how to apply and follow the GNU GPL, see 667 | . 668 | 669 | The GNU General Public License does not permit incorporating your program 670 | into proprietary programs. If your program is a subroutine library, you 671 | may consider it more useful to permit linking proprietary applications with 672 | the library. If this is what you want to do, use the GNU Lesser General 673 | Public License instead of this License. But first, please read 674 | . 675 | 676 | --------------------------------------------------------------------------------